1 citations
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October 2024 in “BMC Pediatrics” In this study, researchers analyzed data from 132 hospitalized kerion patients over 11 years, mostly children under 11 from rural areas, and noted a significant male predominance and frequent animal contact as potential transmission factors.
1 citations
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December 2022 in “Life” This review systematically analyzed evidence on treatment options for erosive pustular dermatosis, finding that while potent topical steroids like clobetasol propionate can be effective, recurrence is common, and more robust studies are necessary for stronger recommendations.
August 2026 in “Dermatology and Therapy” This review discusses current and emerging treatments for discoid lupus erythematosus, suggesting that new biologic and small-molecule therapies may improve disease control when combined with traditional management.
April 2026 in “Biomedicines” This study introduces a novel holistic treatment approach for keloid that combines systemic therapies, including Traditional Chinese Medicine, with local interventions to target the inflammatory microenvironment and keloid predisposition for improved management and prevention of recurrence.
June 2025 in “Frontiers in Immunology” This study reported that anti-Ku-positive patients exhibited heterogeneous muscular features, primarily characterized by necrotizing fibers and vacuolar changes, and suggested that autophagy could be a significant mechanism involved in the pathogenesis.
November 2018 in “Journal of investigative dermatology, venereology and cosmetology” This study found that Biofield Energy Healing significantly increased the proliferation of human hair follicle dermal papilla cells in vitro, suggesting it may promote hair growth.
June 2025 in “Dermatopathology” This study reports that SARS-CoV-2 infection, COVID-19 vaccination, and off-label dupilumab treatment may exacerbate psoriasis, with overlapping inflammatory pathways involving cytokines like IL-17 and TNF-α. Histopathological similarities between psoriasis flares and COVID-19 skin manifestations were noted, suggesting a potential connection requiring further research.
1 citations
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July 2025 in “Barrier Immunity” This review synthesizes existing research on the multilayered defense system of the skin, highlighting how physical, chemical, immune, and microbial barriers work together to maintain skin health, with disruptions in one often leading to broader barrier dysfunctions.
March 2026 in “Biomedicines” This review synthesizes current evidence on therapies for dissecting cellulitis of the scalp, noting that biologics show promise for treatment-resistant cases, though systemic retinoids remain the first-line therapy.
45 citations
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May 2024 in “International Journal of Molecular Sciences” This manuscript reviews the latest understanding of alopecia areata's pathogenesis, highlighting the roles of genetic, immunological, and environmental factors, with a focus on immune responses involving IFN-γ and cytotoxic CD8+ T-cells as key contributors to hair follicle inflammation and function disruption without follicle destruction.
7 citations
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December 2024 in “Antibiotics” This review discusses the potential of cathelicidins in treating skin conditions but highlights significant challenges, including unclear clinical efficacy, safety concerns, and bacterial resistance, that must be addressed for successful medical application.
1 citations
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October 2022 in “International Journal of Molecular Sciences” This study suggests that allogenic human mesenchymal stem cell treatments have potential therapeutic effects by inducing immune tolerance and anti-inflammatory effects in severe alopecia areata patients.
February 2026 in “Stem Cell Research & Therapy” This review article discusses recent advances in stem cell-based therapies for Alopecia Areata, noting preliminary clinical trials show significant hair regrowth, but emphasizes the need for thorough evaluation of long-term safety and efficacy.
137 citations
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January 2006 in “Frontiers in bioscience” This review discusses the role of corticotropin-releasing hormone in human skin, focusing on its regulation, receptors, and functions, and highlights parallels with the hypothalamo-pituitary-adrenal axis; it reports no new research findings.
May 2024 in “International Journal of Molecular Sciences” This study found that injecting mouse hair follicle-derived mesenchymal stem cells (moMSCORS) into C57BL/6 mice reduced the incidence and severity of type 1 diabetes by modulating immune responses, suggesting potential for therapeutic use due to their immunosuppressive effects.
256 citations
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March 2019 in “Journal of the American Academy of Dermatology” This review provides graded evidence and a therapeutic algorithm for managing hidradenitis suppurativa, but does not present new clinical results.
164 citations
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February 2019 in “Anais Brasileiros de Dermatologia” This study produced a guide for managing adult female acne, addressing its complex nature compared to teenage acne, and providing detailed recommendations on diagnosis and treatment. The authors noted that further research is needed to better understand the condition.
28 citations
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April 2023 in “Stem cell research & therapy” This study reviews the roles and mechanisms of MSC-derived exosomes in wound healing, noting their potential as promising cell-free therapies for cutaneous regeneration.
26 citations
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February 2021 in “FEBS Journal” This review discusses potential immune therapies targeting regulatory T cells for age-related diseases and emphasizes the need for further research to translate these therapies into clinical practice.
19 citations
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December 2021 in “Stem Cell Research & Therapy” This study found that Muse cells, when injected subcutaneously, alleviated symptoms of atopic dermatitis in mice, suggesting potential for treating inflammatory skin conditions.
16 citations
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June 2025 in “Journal of Composites Science” This study investigated chitosan–hydroxyapatite biocomposites, finding them to enhance anti-inflammatory cytokine expression, support cellular activities, and reduce pro-inflammatory cytokines in a dermatitis model, while highlighting gaps in understanding their immune modulation and issues with reproducibility for clinical use.
9 citations
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May 2023 in “Stem Cell Research & Therapy” This study found that mesenchymal stem cell treatment alleviated atopic dermatitis-like symptoms in a mouse model by modulating immune and inflammatory responses, with gene expression changes suggesting pathways for potential personalized treatment approaches.
7 citations
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March 2001 in “Journal of the European Academy of Dermatology and Venereology” This case report highlights the complexity of lupus erythematosus/lichen planus overlap syndrome, noting a high potential for progression to systemic lupus erythematosus.
3 citations
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May 2023 in “International Journal of Molecular Sciences” In this study, researchers observed that phospholipid-calcium carbonate hybrid nanoparticles effectively delivered Tofacitinib citrate topically, which significantly inhibited hair follicle apoptosis and promoted hair growth in a mouse model of chemotherapy-induced alopecia, compared to a traditional Tofacitinib solution.
1 citations
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August 2025 in “Frontiers in Bioengineering and Biotechnology” This study found that a 3D wound model, the 3DWoundSE, showed improved responsiveness to injury and cytotoxic stimuli compared to an intact 3D skin equivalent, offering a reproducible and ethical alternative to animal models for early wound response assessment in dermatological research and drug development.
1 citations
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November 2024 in “Orphanet Journal of Rare Diseases” Changes in genes FGA, VWF, and ACTG1 may contribute to pemphigus vulgaris.
1 citations
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December 2023 in “International journal of molecular sciences” In this study, researchers found that miR-199a-3p plays a regulatory role in hair follicle development via the PTPRF/β-catenin axis and established a mouse model of alopecia areata by downregulating this small RNA, suggesting its potential value in studying alopecia diseases.
This study suggests that bio-nanovesicles, such as exosomes and microvesicles, may enhance skin and hair follicle regeneration by modulating key signaling pathways, potentially overcoming the limitations of conventional treatments for alopecia and chronic skin diseases.
December 2025 in “Antibiotics” In this systematic review, researchers found that Tinea capitis in individuals aged 65 or older is frequently misdiagnosed, primarily affects women, and often presents with inflammatory symptoms; systemic antifungal therapy led to clinical cure in 91.2% of cases.
In this preclinical study, PA-011 derived from Periplaneta americana showed significant hair regrowth effects in androgenetic alopecia mouse models by inhibiting inflammation and oxidative stress, activating hair follicle stem cell proliferation, and normalizing skin microbiota, suggesting promise as an AGA treatment.