Infliximab was effective in treating a scalp condition that did not respond to other treatments.
15 citations
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January 2019 in “Journal of the Formosan Medical Association” This case study reports that adding adalimumab to a 12-year-old VKH patient's treatment allowed for ocular inflammation remission, vision improvement, and corticosteroid tapering, suggesting escalation of immunosuppression may be critical in pediatric VKH cases.
In this preclinical study, PA-011 derived from Periplaneta americana showed significant hair regrowth effects in androgenetic alopecia mouse models by inhibiting inflammation and oxidative stress, activating hair follicle stem cell proliferation, and normalizing skin microbiota, suggesting promise as an AGA treatment.
January 2019 in “Springer eBooks” Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.
September 2017 in “Journal of Investigative Dermatology” This study suggests that sweat glands may have an immune privilege similar to hair follicles, and disruptions in this could contribute to autoimmune skin diseases.
January 2024 in “Journal of Clinical Rheumatology and Immunology” In this case report, researchers described a severe case of myelosuppression and alopecia totalis in a patient with systemic lupus erythematosus following azathioprine treatment, highlighting the importance of monitoring for these uncommon side effects.
76 citations
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November 2009 in “Medical Clinics of North America” This article reviews the hormonal and medication-related factors associated with acne development but does not present new research findings.
24 citations
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July 1987 in “Dermatologic Clinics” This article reviews various causes of hair loss linked to systemic factors, noting that careful history and examination can lead to accurate diagnosis, but reports no new clinical results.
November 2024 in “Indian Journal of Rheumatology” This study reported that primary care physicians' lack of knowledge about rheumatology and referrals to other specialties are major factors delaying systemic lupus erythematosus patients' access to rheumatology care in India.
3 citations
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March 2022 in “Annals of Medicine” This study suggests that telogen effluvium is more closely related to the severity of COVID-19 and associated inflammation than to hormonal factors, with women showing a higher prevalence.
1 citations
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May 2022 in “European Journal of Dermatology” This study found that while no predictive factors for response to vismodegib were identified, longer treatment duration was associated with a lower risk of relapse in basal cell carcinoma patients.
41 citations
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January 2022 in “Clinical Immunology” Females are more prone to lupus and arthritis due to X chromosome factors.
33 citations
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January 2011 in “Elsevier eBooks” This article reviews the complexity and diverse manifestations of systemic lupus erythematosus, highlighting potential genetic, hormonal, and environmental factors in its pathogenesis without presenting new clinical findings.
2 citations
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April 2023 in “Expert Review of Clinical Immunology” This review details how baricitinib successfully demonstrated significant hair regrowth in clinical trials for severe alopecia areata, now leading to its approval as the first systemic therapy for the condition, while also highlighting the importance of assessing individual risk factors for adverse events.
February 2024 in “Journal of dermatology” In this case report, a 36-year-old woman with systemic lupus erythematosus and alopecia related to discoid lupus erythematosus showed hair regrowth following treatment with concentrated growth factor, suggesting its potential as a cosmetic therapy for DLE.
February 2024 in “Journal of Paediatrics and Child Health” This case report suggests the co-occurrence of systemic lupus erythematosus and an eating disorder in an adolescent may be linked through shared adolescent stress factors rather than neuropsychiatric lupus, despite algorithmic indications.
32 citations
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June 2012 in “PLoS ONE” This study found that locally injected zalutumumab in healthy volunteers induced a papulopustular rash similar to systemic EGFR inhibitors, and that IL-8 inhibition reduced this dermatological side effect.
12 citations
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July 2015 in “Tissue Antigens” In this study, the AA genotype of C2 polymorphism was more frequently observed in Chinese patients with systemic lupus erythematosus than controls, indicating it may be a risk factor for the disease.
February 2025 in “Indian Dermatology Online Journal” This case report describes a rare occurrence of pincer nail deformity in a patient with systemic lupus erythematosus, potentially linked to Raynaud's phenomena as a contributing factor.
227 citations
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November 2004 in “Medicine” This study found that late-onset systemic lupus erythematosus in a French cohort was characterized by a lower disease severity but reduced survival mainly attributed to aging-related factors.
107 citations
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June 1997 in “PubMed” In this study, disrupting the epidermal growth factor receptor in mice led to abnormal hair and skin development, characterized by disorganized hair follicles and systemic disease, providing a model for understanding EGFR's role in skin biology.
15 citations
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July 1998 in “PubMed” This study found that fentanyl accumulates differently in mouse hair after systemic administration compared to external loading, suggesting ionizable functionalities of hair influence drug retention from organic solutions.
1 citations
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January 2017 in “Expert opinion on orphan drugs” This study reviews current systemic treatments for hidradenitis suppurativa, highlighting traditional methods and new options like biological agents, and suggests that pharmacological therapies show promise, particularly for non-advanced cases, despite the disease's complex etiology involving factors such as genetics and inflammation.
1 citations
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November 2015 in “European medical journal” This article reviews the complex role of various biological, genetic, and environmental factors in acne pathogenesis and notes no new clinical results.
This study found that a hair growth rate of 0.75 cm/month better matches retrospective cortisol timelines and identified factors influencing hair cortisol content in children and adolescents.
33 citations
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October 2018 in “BMJ Case Reports” This case report describes a 6-year-old who developed autoimmune conditions including type III polyglandular autoimmune syndrome following drug-induced hypersensitivity syndrome, prompting an investigation into associated triggering factors.
This review highlights that iron deficiency is a significant yet often overlooked contributor to the development of immune-mediated inflammatory skin diseases, suggesting that iron dysregulation may drive inflammation and metabolic imbalances in conditions like psoriasis and atopic dermatitis.
July 2020 in “International Journal of Research” This review examines the development of cardiovascular risk factors related to testosterone levels in PCOS women and reports no new clinical results.
January 2014 in “Journal of Pigmentary Disorders” This review discusses age-related and environmental factors affecting scalp hair changes in women, highlighting diagnostic complexities and ongoing research into targeted treatments, without reporting new clinical results.
122 citations
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November 1984 in “Journal of the American Academy of Dermatology” This review discusses the potential autoimmune pathogenesis and various contributing factors of alopecia areata, noting that current treatments remain palliative while emerging therapies offer new hope for extensive cases.