June 2026 in “Discover Nano” This review discusses current treatment strategies for alopecia and highlights the potential of lipid-based nanoparticles to improve drug delivery to the scalp and hair follicles, noting their ability to enhance skin penetration and drug stability while outlining associated challenges and the need for further research.
December 2025 in “JEADV Clinical Practice” This review reports that innovative topical treatments for dermatologic conditions like acne and atopic dermatitis show minimal systemic absorption, indicating improved safety and tolerability compared to traditional therapies.
December 2023 in “International Journal of Biomedicine” In this review, researchers explored the potential of topical finasteride as an innovative treatment for male pattern hair loss, addressing the limitations of oral finasteride, such as side effects and inconsistent effectiveness.
January 2019 in “Springer eBooks” Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.
April 2017 in “Journal of Investigative Dermatology” In this study, HPH-15, a newly synthesized compound, demonstrated potential in reducing skin fibrosis in a mouse model by targeting underlying pathogenic mechanisms and exhibited a good safety profile, warranting further clinical trials for fibrotic skin disorders like systemic sclerosis.
This article reviews the spectrum of connective tissue disorders and discusses the role of autoantibodies, particularly in lupus erythematosus, but reports no new findings.
208 citations
,
July 2001 in “Journal of The American Academy of Dermatology” This review discusses the classification and diagnosis of pregnancy-related skin conditions and reports no new clinical findings.
88 citations
,
January 2011 in “Annals of Dermatology” This review discusses the reclassification of pregnancy-related skin diseases and provides a management algorithm but reports no new clinical findings.
74 citations
,
January 2014 in “Journal of Investigative Dermatology” High kallistatin levels in diabetics worsen wound healing by blocking important cell signals.
52 citations
,
June 1981 in “International Journal of Dermatology” Oral retinoids are effective for severe skin conditions but require careful use due to side effects.
51 citations
,
October 1981 in “British Journal of Dermatology” This study found that in patients who underwent jejuno-ileal bypass for morbid obesity, dapsone was effective in treating inflammatory skin lesions and joint symptoms when other antibiotics failed.
42 citations
,
January 1998 in “BioDrugs” Azathioprine's effectiveness and safety require careful monitoring and more research, especially regarding its use with corticosteroids and the role of TPMT status in patients.
33 citations
,
August 2006 in “Journal der Deutschen Dermatologischen Gesellschaft” Pregnancy can cause specific skin conditions that need correct diagnosis and treatment to protect both mother and baby.
26 citations
,
January 2013 in “BMJ Open” This meta-analysis reports that vertex baldness is associated with an increased risk of coronary heart disease, particularly in younger men, while no significant link was found for frontal baldness.
24 citations
,
July 2019 in “Cochrane library” This review found that oral methotrexate plus oral prednisone may improve disease activity or damage in juvenile active morphea compared to placebo plus prednisone, but adverse events may slightly increase.
20 citations
,
April 2021 in “Journal of Womens Health” This guideline provides evidence-based recommendations for prescribing testosterone therapy to women with hypoactive sexual desire disorder, noting a moderate therapeutic benefit but highlighting limited data and regulatory challenges.
19 citations
,
October 1994 in “Tumori Journal” This review discusses the current medical treatments for hepatocellular carcinoma, noting that while new local therapies show high response rates, their true impact on patient survival is uncertain.
17 citations
,
January 2019 in “Annals of Dermatology” This study found that higher serum CXCL10 levels may predict the progression of non-segmental vitiligo, especially in patients also suffering from autoimmune thyroid disease and/or alopecia areata.
16 citations
,
May 2019 in “International Journal of Women's Dermatology” This study reviewed and categorized dermatological drugs for pregnancy and lactation according to new FDA labeling guidelines, which replaced simplistic letter categories with detailed information, aiming to improve prescribing decisions by addressing both maternal and paternal reproductive potential.
15 citations
,
June 2014 in “Integrative cancer therapies” This study found that an 8-week practice of pranic meditation was associated with improved quality of life and mental health scores in breast cancer survivors, though further research is needed for confirmation.
11 citations
,
February 2003 in “Baillière's best practice & research. Clinical obstetrics & gynaecology/Baillière's best practice and research in clinical obstetrics and gynaecology” This review discusses the relationship between acne, body hair, and androgenic stimulation in adolescent girls, emphasizing treatment decisions based on disease severity rather than endocrine findings.
9 citations
,
April 2021 in “Climacteric” This study provides a guideline for the safe and effective use of testosterone in women with hypoactive sexual desire disorder, recommending systemic transdermal testosterone for appropriate candidates while highlighting the importance of informed consent and monitoring due to unestablished long-term safety.
4 citations
,
June 2025 in “Frontiers in Immunology” This review discusses the role of the BAFF system in autoimmune diseases and highlights its therapeutic potential, emphasizing the need for disease-specific clinical trials to improve treatment strategies.
4 citations
,
July 2022 in “International Journal of Health Sciences” This review discusses rosemary's potential health benefits, including improved scalp circulation and skin protection, but reports no new clinical findings and highlights the need for better regulation and safety data on herbal medicines.
4 citations
,
January 2015 in “Case Reports in Rheumatology” This case report highlights that early recognition and management of underlying connective tissue diseases, such as lupus, are essential in young patients presenting with unexpected symptoms like blurry vision and stroke signs.
3 citations
,
February 2008 in “Basic and clinical dermatology” Telogen Effluvium is a hair loss condition where treatment involves identifying and managing its triggers.
2 citations
,
September 2015 in “Clínica e Investigación en Arteriosclerosis” This review discusses the association between certain dermatological diseases and increased cardiovascular risk, highlighting the need for clinicians to address cardiovascular risk factors in these patients.
1 citations
,
October 2025 in “International Journal of Nanomedicine” This review explores the potential for using exosomes in treating autoimmune skin diseases and promoting skin regeneration, highlighting current applications, delivery methods, and ongoing clinical trials while also identifying challenges and future research directions within dermatology.
1 citations
,
January 2019 in “Przegla̧d dermatologiczny” This article reviews the concept of cardiodermatology and its application in clinical practice but does not present new empirical findings.
1 citations
,
October 1996 in “Journal of Cutaneous Medicine and Surgery” This review discusses the advancements needed for gene therapy to become commonly used in dermatology and reports no new clinical results.