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      Protoporphyrin IX: The Good, the Bad, and the Ugly

      research Protoporphyrin IX: the Good, the Bad, and the Ugly

      138 citations , November 2015 in “Journal of Pharmacology and Experimental Therapeutics”
      This review discusses the mechanisms associated with protoporphyrin IX in living cells and reports no clinical results; the authors emphasize its potential in cancer diagnosis and the risks of toxicity.
      Androgenetic Alopecia and Microinflammation

      research Androgenetic alopecia and microinflammation

      131 citations , August 2000 in “International Journal of Dermatology”
      Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.
      The Circadian Clock in Skin

      research The Circadian Clock in Skin

      127 citations , January 2015 in “Journal of Biological Rhythms”
      This review discusses the role of the circadian clock in skin functions such as cell proliferation and UV protection and reports no new results; the authors note its potential in studying immune regulation and seasonal behaviors.
      Cell Death in the Skin: Mechanisms and Implications

      research Cell death in the skin

      120 citations , February 2009 in “Apoptosis”
      This review examines apoptotic and anti-apoptotic mechanisms in skin homeostasis and related diseases but presents no new research findings.
      Extraskeletal Actions of Vitamin D

      research Extraskeletal actions of vitamin D

      119 citations , July 2016 in “Annals of the New York Academy of Sciences”
      This review examines the impact of vitamin D signaling in extraskeletal tissues and notes that expected benefits from animal and cell studies have not been consistently replicated in human clinical trials.
      New Antifungal Agents and Formulations Against Dermatophytes

      research New Antifungal Agents and New Formulations Against Dermatophytes

      113 citations , August 2016 in “Mycopathologia”
      This review discusses the developments in antifungal treatments for dermatophyte infections since 2008, reporting no new oral agents but introducing newer topical options like efinaconazole and tavaborole.
      Folliculitis Decalvans: A Rare Inflammatory Scalp Disorder

      research Folliculitis decalvans

      112 citations , July 2008 in “Dermatologic Therapy”
      This review outlines the diagnosis and management of folliculitis decalvans, an inflammatory scalp disorder, and highlights Staphylococcus aureus and immune response deficiencies as key factors in its development.
      Regulatory T Cells in Skin: Role of Foxp3+ CD4+ Tregs in Skin Homeostasis and Immune Tolerance

      research Regulatory T cells in skin

      110 citations , July 2017 in “Immunology”
      This review discusses the role of regulatory T cells in skin, including their impact on hair follicle regeneration, wound healing, and immune tolerance, without presenting new clinical findings.
      Fullerene Nanoparticles in Dermatological and Cosmetic Applications

      research Fullerene nanoparticle in dermatological and cosmetic applications

      101 citations , October 2016 in “Nanomedicine: Nanotechnology, Biology and Medicine”
      This review reports on the dual aspect of fullerene in skincare, highlighting its beneficial antioxidant properties as well as potential toxicity and skin cell reactions, while identifying areas for future research.
      Aging of Hair

      research Aging of hair

      99 citations , June 2005 in “Journal of Cosmetic Dermatology”
      This article reviews factors influencing hair aging and available treatments like minoxidil and finasteride for androgenetic alopecia but reports no new clinical results.
      Beyond Acne: Current Aspects of Sebaceous Gland Biology and Function

      research Beyond acne: Current aspects of sebaceous gland biology and function

      97 citations , September 2016 in “Reviews in Endocrine and Metabolic Disorders”
      This review summarizes recent multidisciplinary advances in sebaceous gland research and highlights potential novel therapeutic strategies for skin diseases, but it reports no new clinical results.
      Primary Cicatricial Alopecia: Treatment Approaches and Classification

      research Primary cicatricial alopecia

      95 citations , November 2016 in “Journal of The American Academy of Dermatology”
      This article reviews primary cicatricial alopecias, focusing on lymphocytic forms such as chronic cutaneous lupus erythematosus, according to a classification by the North American Hair Research Society, and reports no new clinical results.
      Tinea Capitis: An Overview with Emphasis on Management

      research Tinea Capitis: An Overview with Emphasis on Management

      89 citations , May 1999 in “Pediatric Dermatology”
      This article reviews the treatment options for tinea capitis, suggesting that itraconazole, terbinafine, and fluconazole are effective and safe alternatives to griseofulvin but reports no new clinical results.
      Evaluation and Diagnosis of the Hair Loss Patient

      research Evaluation and diagnosis of the hair loss patient

      86 citations , August 2014 in “Journal of The American Academy of Dermatology”
      This article discusses the history taking and clinical examination process for diagnosing alopecia and outlines a diagnostic approach, noting that it reports no new clinical results.
      Severe Acute Respiratory Syndrome (SARS)

      research Severe Acute Respiratory Syndrome (SARS)

      84 citations , March 2010 in “Infectious Disease Clinics of North America”
      The document concludes that rapid identification, isolation, and strict infection control are crucial to manage SARS outbreaks.
      Human αβ and γδ T Cells in Skin Immunity and Disease

      research Human αβ and γδ T Cells in Skin Immunity and Disease

      83 citations , June 2018 in “Frontiers in immunology”
      This review discusses the roles of αβ and γδ T cells in skin health and disease and reports no new clinical results; the authors highlight potential therapeutic developments.
      What Causes Hidradenitis Suppurativa?—15 Years After

      research What causes hidradenitis suppurativa ?—15 years after

      78 citations , October 2020 in “Experimental Dermatology”
      This review summarizes 15 years of clinical and experimental research advancements in hidradenitis suppurativa, highlighting its recognition as a uniquely healable inflammatory skin disease but reports no new clinical results.
      Clinical and Biological Impact of the Exposome on the Skin

      research Clinical and biological impact of the exposome on the skin

      77 citations , July 2020 in “Journal of the European Academy of Dermatology and Venereology”
      This review examines the skin exposome, including solar exposure, air pollution, hormones, nutrition, and psychological factors, but reports no new clinical results.
      Regulated Proenkephalin Expression in Human Skin and Cultured Skin Cells

      research Regulated Proenkephalin Expression in Human Skin and Cultured Skin Cells

      77 citations , December 2010 in “˜The œjournal of investigative dermatology/Journal of investigative dermatology”
      This study found that human skin expresses proenkephalin, whose expression is upregulated by environmental stress and varies in pathological conditions, increasing in psoriasis and decreasing in melanocytic tumors.