2 citations
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October 2021 in “Journal of skin and stem cell” This study observed that nail abnormalities often indicate underlying dermatological or systemic conditions, with psoriasis and infections being the most common causes among patients.
September 2025 in “Frontiers in Cell and Developmental Biology” In this review, retinoids are highlighted as promising agents for promoting scarless skin regeneration by coordinating cellular and molecular processes that suppress fibrosis, enhance re-epithelialization, promote angiogenesis, and enable hair follicle formation, potentially advancing functional skin repair.
February 2023 in “Materials today bio” In this study, researchers developed a promising transdermal agent using Triton X-100-modified polyethyleneimine that successfully delivered genetic material to hair follicle cells in mice, potentially alleviating hair loss due to androgenetic alopecia by promoting cell proliferation and inhibiting apoptosis.
January 2026 in “Journal of Community Medicine and Health Solutions” In this study, the novel topical agent PP405 showed favorable tolerability and increased hair density by over 20% in men with advanced androgenetic alopecia after eight weeks, suggesting a promising potential treatment pending further trials.
33 citations
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April 2017 in “American journal of clinical dermatology” This study suggests that deep dermatophytosis is a distinct condition occurring in immunocompromised patients, characterized by nodules, an indolent course, and absence of follicular invasion, which resolves completely with systemic antifungal treatment.
31 citations
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March 2015 in “The Journal of Steroid Biochemistry and Molecular Biology” This review discusses the complexity of neuroactive steroid therapies for neuroprotection and reports no new clinical findings, suggesting potential unexpected effects in the brain compared to systemic levels.
31 citations
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August 1963 in “Archives of Dermatology” This report describes two patients with alopecia universalis, onychodystrophy, and vitiligo, and found no underlying systemic or etiological causes through extensive investigations.
28 citations
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January 2005 in “PubMed” This review discusses the use, mechanism, and side effects of topical immunomodulators in treating immune-mediated skin disorders and reports no new clinical results, urging further research on experimental agents.
27 citations
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June 2017 in “Expert opinion on investigational drugs” This review discusses ongoing and past trials for novel acne treatments, focusing on topical agents with potential sebosuppressive, antimicrobial, or anti-inflammatory effects, without reporting new clinical results.
8 citations
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November 2024 in “Journal of Neuroendocrinology” This review discusses the role of gut steroids in communicating with the gut microbiota and their potential implications in treating gastrointestinal disorders and related brain conditions, suggesting new perspectives on steroid molecules as therapeutic agents.
September 2025 in “BULLETIN OF STOMATOLOGY AND MAXILLOFACIAL SURGERY” In this review, researchers explored the complex mechanisms behind chemotherapy-induced side effects like nausea, fatigue, and hair loss, and discussed potential strategies using natural agents to manage these toxicities, improving understanding for targeted adjunct therapies.
December 2024 in “Dermatological Reviews” This review highlights significant advances in understanding and treating Alopecia Areata, emphasizing the effectiveness of JAK inhibitors like baricitinib, ritlecitinib, and deuruxolitinib for systemic treatment, while also noting ongoing research into new therapeutic approaches such as stem cell therapy and energy-assisted drug delivery.
This review discusses various skin-related conditions affecting hair and nails, highlighting associations with systemic pathologies but reports no new clinical findings.
February 2026 in “Scientific Messenger of LNU of Veterinary Medicine and Biotechnology” This review discusses the diagnosis and treatment of dermatophytosis in cats, highlighting the susceptibility of Persian and young cats and the use of antifungal agents and new therapies.
513 citations
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February 2022 in “Advanced Science” This study demonstrated that incorporating PDA@Ag nanoparticles into a cationic guar gum hydrogel significantly enhanced photothermal conversion efficiency, achieving superior antibacterial efficacy both in vitro and in vivo, advancing the potential of PDA as a photothermal antibacterial agent.
25 citations
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March 2019 in “Dermatologic therapy” This study reviewed the current state of intralesional therapy for keratoacanthoma, finding that while methotrexate, 5-fluorouracil, and interferon alpha are common agents, guidelines are still needed, and histopathological confirmation is advised to prevent misdiagnosis with squamous cell carcinoma.
2 citations
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May 2020 in “JAAD case reports” This review discusses the potential role of JAK inhibitors, like ruxolitinib, as emerging therapeutic agents in dermatology, but reports no new clinical results.
March 2026 in “Preprints.org” In this study, plerixafor was found to enhance melanogenesis and promote repigmentation by engaging a β-arrestin–β-catenin–MITF signaling axis in melanocytes, and showed effectiveness in restoring depigmentation in a murine model without causing systemic toxicity.
July 2024 in “Forum Dermatologicum” This review evaluates various topical treatments for androgenetic alopecia but does not provide new clinical findings, emphasizing the need for selecting therapies with limited systemic side effects.
August 2025 in “Anais Brasileiros de Dermatologia” This review details phenol's dermatological uses and underscores its potent skin rejuvenation effects but emphasizes the need for caution due to risks of serious complications, including cardiac arrhythmias and organ failure, particularly with improper use or large-area applications.
January 2019 in “Przegląd Dermatologiczny” This article reviews clinical issues and dermatologist perspectives on managing periungual lesions in patients undergoing docetaxel chemotherapy, but it reports no new clinical outcomes.
January 2004 in “Journal of Clinical Dermatology” This study reported a case of a 34-year-old male developing allergic contact dermatitis to minoxidil solution, with positive patch test reactions attributed to the solution's ingredients, highlighting the potential for propylene glycol sensitivity.
February 2020 in “Oncology Times” This article reviews antibody drug conjugates for cancer treatment, describing their mechanism, recent approvals, and ongoing research efforts, but reports no new clinical results.
9 citations
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August 2002 in “Current Opinion in Pediatrics” This article discusses the roles of pediatrics and dermatology departments at Yale University School of Medicine, but reports no specific clinical results.
In this study, a 34-year-old male developed allergic contact dermatitis on the scalp after using minoxidil solution for androgenic alopecia, with the reaction potentially linked to the propylene glycol in the product.
2 citations
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November 2025 in “Pharmaceutics” This review explores the potential of cell-mediated drug delivery systems in dermatology, highlighting their ability to target inflamed or diseased skin while discussing applications in diseases like atopic dermatitis and melanoma, along with challenges such as immunogenicity and manufacturing.
Use the least toxic, most specific treatments for skin diseases, considering side effects and individual patient needs.
14 citations
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November 2018 in “Journal of drug delivery and therapeutics” This article reviewed the preparation, application, and characterization of ethosomes as drug delivery transporters and reported that in a double-blind randomized clinical study, ethosomal acyclovir significantly improved all evaluated parameters in skin delivery, highlighting potential for novel therapies.
13 citations
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March 2011 in “Acta Paediatrica” This case report describes a 5-year-old girl who developed kerion celsi from an untreated scalp infection, likely contracted from a guinea pig, leading to significant hair loss and the need for a wig.
4 citations
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October 2007 in “Dermatologic Clinics” This review discusses the roles of glucocorticoid and sex hormone receptors in the skin and their clinical importance, but reports no new research findings.