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      Retinoids in Scarless Skin Regeneration: From Molecular Mechanisms to Therapeutic Strategies

      research Retinoids in scarless skin regeneration: from molecular mechanisms to therapeutic strategies

      September 2025 in “Frontiers in Cell and Developmental Biology”
      In this review, retinoids are highlighted as promising agents for promoting scarless skin regeneration by coordinating cellular and molecular processes that suppress fibrosis, enhance re-epithelialization, promote angiogenesis, and enable hair follicle formation, potentially advancing functional skin repair.

      research Triton modified polyethyleneimine conjugates assembled with growth arrest-specific protein 6 for androgenetic alopecia transdermal gene therapy

      February 2023 in “Materials today bio”
      In this study, researchers developed a promising transdermal agent using Triton X-100-modified polyethyleneimine that successfully delivered genetic material to hair follicle cells in mice, potentially alleviating hair loss due to androgenetic alopecia by promoting cell proliferation and inhibiting apoptosis.
      PP405 in Alopecia: An Emerging Molecule Worth Investigating

      research PP405 in Alopecia: An Emerging Molecule worth Investigating

      January 2026 in “Journal of Community Medicine and Health Solutions”
      In this study, the novel topical agent PP405 showed favorable tolerability and increased hair density by over 20% in men with advanced androgenetic alopecia after eight weeks, suggesting a promising potential treatment pending further trials.
      New Steps Forward in the Neuroactive Steroid Field

      research New steps forward in the neuroactive steroid field

      31 citations , March 2015 in “The Journal of Steroid Biochemistry and Molecular Biology”
      This review discusses the complexity of neuroactive steroid therapies for neuroprotection and reports no new clinical findings, suggesting potential unexpected effects in the brain compared to systemic levels.

      research Alopecia Universalis, Onychodystrophy, and Total Vitiligo

      31 citations , August 1963 in “Archives of Dermatology”
      This report describes two patients with alopecia universalis, onychodystrophy, and vitiligo, and found no underlying systemic or etiological causes through extensive investigations.

      research Topical immunomodulators in dermatology.

      28 citations , January 2005 in “PubMed”
      This review discusses the use, mechanism, and side effects of topical immunomodulators in treating immune-mediated skin disorders and reports no new clinical results, urging further research on experimental agents.

      research Anti-acne drugs in phase 1 and 2 clinical trials

      27 citations , June 2017 in “Expert opinion on investigational drugs”
      This review discusses ongoing and past trials for novel acne treatments, focusing on topical agents with potential sebosuppressive, antimicrobial, or anti-inflammatory effects, without reporting new clinical results.

      research The gut‐microbiota‐brain axis: Focus on gut steroids

      8 citations , November 2024 in “Journal of Neuroendocrinology”
      This review discusses the role of gut steroids in communicating with the gut microbiota and their potential implications in treating gastrointestinal disorders and related brain conditions, suggesting new perspectives on steroid molecules as therapeutic agents.
      Alopecia Areata Treatment: Past, Present, And Future

      research Alopecia Areata Treatment: Past, Present, and Future

      December 2024 in “Dermatological Reviews”
      This review highlights significant advances in understanding and treating Alopecia Areata, emphasizing the effectiveness of JAK inhibitors like baricitinib, ritlecitinib, and deuruxolitinib for systemic treatment, while also noting ongoing research into new therapeutic approaches such as stem cell therapy and energy-assisted drug delivery.
      Nails and Hair

      research Nails and hair

      June 2013 in “Medicine”
      This review discusses various skin-related conditions affecting hair and nails, highlighting associations with systemic pathologies but reports no new clinical findings.

      research Pathogenesis, diagnosis and pharmacotherapy of dermatophytosis in cats

      February 2026 in “Scientific Messenger of LNU of Veterinary Medicine and Biotechnology”
      This review discusses the diagnosis and treatment of dermatophytosis in cats, highlighting the susceptibility of Persian and young cats and the use of antifungal agents and new therapies.
      Intralesional Therapy for the Treatment of Keratoacanthoma

      research Intralesional therapy for the treatment of keratoacanthoma

      25 citations , March 2019 in “Dermatologic therapy”
      This study reviewed the current state of intralesional therapy for keratoacanthoma, finding that while methotrexate, 5-fluorouracil, and interferon alpha are common agents, guidelines are still needed, and histopathological confirmation is advised to prevent misdiagnosis with squamous cell carcinoma.

      research Phenol in dermatology: updated evidence on efficacy and safety

      August 2025 in “Anais Brasileiros de Dermatologia”
      This review details phenol's dermatological uses and underscores its potent skin rejuvenation effects but emphasizes the need for caution due to risks of serious complications, including cardiac arrhythmias and organ failure, particularly with improper use or large-area applications.
      Periungual Lesions Secondary to Chemotherapy with Docetaxel

      research Periungual lesions secondary to chemotherapy with docetaxel

      January 2019 in “Przegląd Dermatologiczny”
      This article reviews clinical issues and dermatologist perspectives on managing periungual lesions in patients undergoing docetaxel chemotherapy, but it reports no new clinical outcomes.
      A Case of Allergic Contact Dermatitis Due to Topical Minoxidil

      research A Case of Allergic Contact Dermatitis Due to Topical Minoxidil

      January 2004 in “Journal of Clinical Dermatology”
      This study reported a case of a 34-year-old male developing allergic contact dermatitis to minoxidil solution, with positive patch test reactions attributed to the solution's ingredients, highlighting the potential for propylene glycol sensitivity.

      research Antibody Drug Conjugates

      February 2020 in “Oncology Times”
      This article reviews antibody drug conjugates for cancer treatment, describing their mechanism, recent approvals, and ongoing research efforts, but reports no new clinical results.
      Case Report: Pemphigus Vulgaris in an Adolescent

      research Case report: pemphigus vulgaris in an adolescent

      9 citations , August 2002 in “Current Opinion in Pediatrics”
      This article discusses the roles of pediatrics and dermatology departments at Yale University School of Medicine, but reports no specific clinical results.
      A Case of Allergic Contact Dermatitis Caused by Topical Minoxidil Solution

      research Minoxidil 외용액에 의한 알레르기성 접촉피부염 1예

      April 2004 in “대한피부과학회지”
      In this study, a 34-year-old male developed allergic contact dermatitis on the scalp after using minoxidil solution for androgenic alopecia, with the reaction potentially linked to the propylene glycol in the product.

      research Ethosome: a novel vesicular carrier for transdermal drug delivery

      14 citations , November 2018 in “Journal of drug delivery and therapeutics”
      This article reviewed the preparation, application, and characterization of ethosomes as drug delivery transporters and reported that in a double-blind randomized clinical study, ethosomal acyclovir significantly improved all evaluated parameters in skin delivery, highlighting potential for novel therapies.