June 2026 in “International Journal of Drug Delivery Technology” In this review, researchers discussed various novel drug delivery systems, including lipid nanocarriers and polymeric nanoparticles, that may enhance treatment for alopecia by improving drug localization in hair follicles and reducing systemic exposure, potentially offering better outcomes than conventional treatments.
March 2026 in “Pharmaceuticals” This study found that the type of reporter significantly influences the detection of cancer therapy-induced alopecia signals, highlighting differences in signal amplification between patients and healthcare professionals.
February 2026 in “Preprints.org” This study analyzed data from the FDA Adverse Event Reporting System to evaluate cancer therapy–induced alopecia, finding that reporter type significantly affects signal detection, with docetaxel showing the highest disproportionate association overall, and vismodegib ranking highest among healthcare professional reports.
August 2025 in “Aesthetic Plastic Surgery” This review explores the mechanisms, current products, challenges, and innovative approaches related to cosmetics for hair loss prevention and growth promotion, emphasizing the need for multidisciplinary cooperation to enhance product development and market success.
January 2025 in “RSC Pharmaceutics” Smart microneedles using advanced tech could improve psoriasis treatment.
September 2023 in “Nature Communications” In this animal study, the researchers found that biodegradable extracellular matrix scaffolds accelerated wound healing and enhanced hair follicle neogenesis in mice, suggesting a role for immune systems in tissue regeneration.
September 2023 in “International journal of Unani and integrative medicine” In this study, researchers observed a possible correlation between hair loss patterns and Mizaj (temperament) types, suggesting that hair loss patterns might serve as a diagnostic index for identifying individual temperaments according to the Unani system of medicine.
October 2021 in “Journal of the European Academy of Dermatology and Venereology” This review discusses the significant progress in the diagnosis and treatment of hair loss disorders over the last 30 years and reports no new clinical results.
January 2021 in “Figshare” This study reported that exposure to melatonin promoted hair follicle fiber growth in an in vitro Cashmere goat model, potentially by influencing pathways related to the extracellular matrix and microvascular system.
April 2018 in “Journal of Investigative Dermatology” This study found that external light can rapidly activate hair follicle stem cells in animals via a retinal light-sensing pathway linked to the central and autonomic nervous systems.
January 2018 in “Figshare” In this study, melatonin exposure promoted hair follicle fiber growth in Cashmere goats, suggesting that it may mediate hair follicle development through long non-coding RNAs affecting vascular and extracellular pathways.
January 2018 in “Figshare” This study found that melatonin exposure promoted growth in Cashmere goat hair follicles in vitro and suggested that lncRNAs play a key role in regulating this process, particularly through pathways involving the microvascular system and extracellular matrix.
April 2026 in “BMC Oral Health” In this case report, a 45-year-old male developed recurrent, painful oral ulcers after starting finasteride for hair loss, with symptoms resolving after stopping the drug and returning upon rechallenge, suggesting a probable causal link.
This study examined the cardiovascular safety of oral minoxidil, used off-label for androgenetic alopecia, particularly as its usage expands in real-world settings, although specific results were not detailed in the abstract.
February 2026 in “Nano Research” This study developed a dissolvable microneedle system delivering specific molecules to remodel lymphatic networks and normalize metabolic processes, which accelerated hair growth and activated hair follicle stem cells in a mouse model of androgenetic alopecia.
This chapter emphasizes the critical role of the integumentary system in animal physiology, detailing its structures, immune functions, and sensory capabilities as crucial for homeostasis, protection, and various physiological processes.
March 2025 in “The Egyptian Journal of Medical Microbiology” This study found that patients with diffuse hair loss had significantly higher serum levels of inflammatory cytokines IL-6 and TNF-α compared to healthy controls, suggesting a potential role of immune system activation in the pathogenesis of this condition.
November 2024 in “ACS Materials Letters” This study developed a nitric oxide delivery system using PVA films and HA liposomes, which enhanced hair follicle vitality and repaired blood vessels in androgenic alopecia by promoting angiogenesis and reducing inflammation through the HIF-1 signaling pathway.
September 2024 in “Journal of the American Academy of Dermatology” This study observed that among patients starting Semaglutide therapy at 0.25-2mg weekly, approximately 0.80-0.83% reported non-scarring hair loss within six months, suggesting the drug does not significantly increase hair loss risk.
August 2024 in “medRxiv (Cold Spring Harbor Laboratory)” This study found that finasteride use is associated with both known and new adverse events, which vary by gender and age, as well as some events not previously listed in the drug insert.
October 2023 in “Facial Plastic Surgery” This article describes the PHAT technique for lip and facial rejuvenation but reports no new clinical findings; the technique aims to improve skin quality and enhance surgical outcomes.
September 2022 in “Research Square (Research Square)” In this study, the DIET-AI model, developed from a large dataset of over 200,000 images, demonstrated diagnostic performance for 31 skin diseases comparable to dermatologists of varying experience levels in 15 hospitals across China, supporting its potential effectiveness in clinical settings.
December 2021 in “The Korean Society of Beauty and Art” In this study, a microneedle patch system using pullulan as a polymer was found to efficiently deliver finasteride, promising convenience and effectiveness in treating hair loss.
September 2021 in “Zenodo (CERN European Organization for Nuclear Research)” This study evaluated a new high-power, 810 nm diode laser for hair removal, finding it to be effective and safe, with a mean hair reduction of 74.4% in one session, and noted it worked efficiently on both large and small areas with minimal side effects.
September 2021 in “World journal of urology” The correction states that the label change for Finasteride was in 2012, leading to more reports of side effects from non-healthcare people.
October 2019 in “DOAJ (DOAJ: Directory of Open Access Journals)” In this study, N-MXD (minoxidil nanoparticles) was shown to deliver more drug into hair bulbs and enhance IGF-1 and VEGF levels more effectively than commercial formulations, resulting in higher therapeutic efficiency for hair growth in C57BL/6 mice.
August 2018 in “Journal of The American Academy of Dermatology” Finasteride use for hair loss is linked to an increased risk of suicidal thoughts and a higher risk of suicide.
This study found that VB-1, a vitexin compound, may promote human hair follicle growth by enhancing Wnt/β-catenin signaling in dermal papilla cells.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that mitochondrial dysfunction might contribute to the pathogenesis of Lichen planopilaris by triggering a metabolic shift that leads to chronic inflammation and hair follicle damage.
January 2005 in “Chinese Journal of Aesthetic Medicine” This study found that hair transplantation using micrografts and minigrafts achieved high patient satisfaction and a graft survival rate of about 90% for different types of hair loss.