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    Glossary Syphilitic Alopecia

    hair loss caused by secondary syphilis infection

    Syphilitic Alopecia, also known as Syphilitic Hair Loss or Alopecia Syphilitica, is a form of hair loss associated with secondary syphilis, a sexually transmitted infection caused by the bacterium Treponema pallidum. It typically presents as patchy hair loss on the scalp, often described as a "moth-eaten" appearance, but can also affect other body hair. This condition is a sign of systemic infection and requires antibiotic treatment to address the underlying syphilis.

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    1. Essential syphilitic alopecia revisited Journal of The American Academy of Dermatology · 1995 · 53 citations
    2. Syphilitic alopecia: uncommon trichoscopic findings Dermatology practical & conceptual · 2017 · 32 citations
    3. Syphilitic Alopecia: Case Reports and Trichoscopic Findings Skin appendage disorders · 2017 · 29 citations
    4. Syphilitic Alopecia: A Report of 5 Cases and a Review of the Literature Actas Dermo-Sifiliográficas · 2013 · 13 citations
    5. Dermatoscopic findings of syphilitic alopecia Anais Brasileiros de Dermatologia · 2020 · 11 citations
    6. Alopecia syphilitica diffusa Infection · 2015 · 6 citations
    7. Epidemiological, Clinical, and Trichoscopic Features of Syphilitic Alopecia: A Retrospective Analysis and Systematic Review Frontiers in Medicine · 2022 · 4 citations
    8. Justified Suspicion: Symptomatic Syphilitic Alopecia in a Patient with Well-Controlled HIV Case Reports in Infectious Diseases · 2021 · 3 citations
    9. Mixed-pattern, essential syphilitic alopecia, uveitis, and papillitis in an immunocompetent patient with neurosyphilis Dermatology Reports · 2025 · 1 citations
    10. Moth-eaten alopecia and beyond: Syphilitic alopecia - Revisited Indian Journal of Sexually Transmitted Diseases and AIDS · 2024 · 1 citations
    11. Trichoscopic Features of Syphilitic Alopecia and Alopecia Areata: A Comparative Study Clinical Cosmetic and Investigational Dermatology · 2023 · 1 citations
    12. Moth-Eaten Symptomatic Syphilitic Alopecia Associated with Human Immunodeficiency Virus—A Case Report Case Reports in Clinical Medicine · 2016 · 1 citations
    13. Syphilitic Alopecia Through the Dermoscope: A Series of two Cases NATIONAL BOARD OF EXAMINATIONS JOURNAL OF MEDICAL SCIENCES · 2025
    14. Navigating diagnostic challenges in syphilitic alopecia: insights from dermoscopy Clinical and Experimental Dermatology · 2023
    15. Syphilitic Alopecia: Report of a Challenging Case and Review of the Literature Journal of clinical and investigative dermatology · 2020
    16. Syphilitic alopecia Informa Healthcare eBooks · 2012
    17. Case Report: Secondary syphilitic alopecia following non-penetrative sexual contact: a case of initial misdiagnosis Frontiers in Medicine · 2026
    18. Frontal Fibrosing Alopecia Mimicking Alopecia Syphilitica Cureus · 2022 · 3 citations
    19. Diffuse pattern essential syphilitic alopecia: an unusual form of secondary syphilis International Journal of Dermatology · 2012 · 10 citations
    20. Essential syphilitic alopecia: Non-scarring alopecia in 21-year-old man Our Dermatology Online · 2021
    21. Alopecia syphilitica, from diagnosis to treatment Baylor University Medical Center Proceedings · 2022 · 1 citations
    22. Moth-eaten essential syphilitic alopecia QJM · 2014 · 3 citations
    23. Histopathology of non-scarring alopecia Journal of Cutaneous Pathology · 1995 · 122 citations
    24. Eosinophils in fibrous tracts and near hair bulbs: A helpful diagnostic feature of alopecia areata Journal of The American Academy of Dermatology · 1997 · 64 citations
    25. Clinical Approach to the Patient With Alopecia Seminars in Cutaneous Medicine and Surgery · 2006 · 21 citations
    26. Histologic Features of Alopecias–Part I: Nonscarring Alopecias Actas Dermo-Sifiliográficas · 2015 · 13 citations
    27. Alopecia as a systemic disease Clinics in Dermatology · 2019 · 7 citations
    28. A guide to distinguish alopecia areata from other hair loss diseases presenting similar clinical manifestations Nihon rinsho hifukaikai zasshi · 2021 · 1 citations
    29. 31-Year-Old Woman With Chronic Daily Headache and Alopecia Mayo Clinic Proceedings · 2013 · 1 citations
    30. Alopecia Areata in a Patient Undergoing Treatment for Secondary Syphilis: A Diagnostic Challenge Cureus · 2026