research Medical Treatments for Male and Female Pattern Hair Loss
Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.
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research A Phase IIA Randomized, Placebo-Controlled Clinical Trial to Study the Efficacy and Safety of the Selective Androgen Receptor Modulator (SARM), MK-0773 in Female Participants with Sarcopenia
MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.
research Penetration of Drugs Through Skin: A Complex Rate-Controlling Membrane
The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.
research HIV Pre-Exposure Prophylaxis in Transgender Women: A Subgroup Analysis of the iPrEx Trial
PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.
research Androgen Receptor Antagonists Structure-Activity Relationships
Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.
research Evaluation and Treatment of Male and Female Pattern Hair Loss
Early diagnosis and treatment, using finasteride, minoxidil, or hair transplantation, improves hair loss outcomes.
research Lecithin Organogels as a Potential Phospholipid-Structured System for Topical Drug Delivery: A Review
Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.
research APCDD1 Is a Novel Wnt Inhibitor Mutated in Hereditary Hypotrichosis Simplex
A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.
research Polycystic Ovarian Syndrome: Correlation Between Hyperandrogenism, Insulin Resistance, and Obesity
High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.
research The ZIP7 Gene (Slc39a7) Encodes a Zinc Transporter Involved in Zinc Homeostasis of the Golgi Apparatus
The ZIP7 gene helps control zinc levels in cells by moving zinc from the Golgi apparatus to the cytoplasm.
research Volatile Signaling by Sesquiterpenes from Ectomycorrhizal Fungi Reprograms Root Architecture
Fungi-produced compounds can change plant root growth.
research Androgen-Inducible TGF-β1 from Balding Dermal Papilla Cells Inhibits Epithelial Cell Growth: A Clue to Understanding Paradoxical Effects of Androgen on Human Hair Growth
Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.
research Generic Development of Topical Dermatologic Products: Formulation Development, Process Development, and Testing
The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.
research Biology of Estrogens in Skin: Implications for Skin Aging
Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.
research Finasteride
Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.
research Melatonin: A Cutaneous Perspective on Its Production, Metabolism, and Functions
Melatonin may benefit skin health and could be a promising treatment in dermatology.
research Tissue Engineering of Human Hair Follicles Using a Biomimetic Developmental Approach
Researchers created human hair follicles using a new method that could help treat hair loss.
research Sulforaphane Mobilizes Cellular Defenses That Protect Skin Against Damage by UV Radiation
Sulforaphane from broccoli can help protect skin from sun damage.
research Essential Oils and Their Single Compounds in Cosmetics: A Critical Review
Essential oils in cosmetics can offer benefits but may cause allergies and should be used carefully.
research Adverse Effects of Opioid Analgesic Drugs
Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.
research Alopecia Areata: Treatment Options and Efficacy
Some treatments can help with a hair loss condition called alopecia areata, but none ensure lasting results; choices depend on the person, with JAK inhibitors showing promise for severe cases.
research The PDGF/PDGFR Pathway as a Drug Target
The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.
research Fibrous Scaffolds Potentiate the Paracrine Function of Mesenchymal Stem Cells: A New Dimension in Cell-Material Interaction
Special fiber materials boost the healing properties of certain stem cells.
research Androgens Protect Against Apolipoprotein E4-Induced Cognitive Deficits
Androgens can help prevent memory problems caused by apoE4.
research Fortnightly Review: Male Pattern Androgenetic Alopecia
Hair loss in men is common, treatable, but not curable.
research Erectile Dysfunction in Young Men: A Review of Prevalence and Risk Factors
Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.
research Action of Isotretinoin in Acne Rosacea and Gram-Negative Folliculitis
Isotretinoin is highly effective in treating severe acne, rosacea, and gram-negative folliculitis.
research A Hot New Twist to Hair Biology: The Role of TRPV1 in Human Hair Growth Control
Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.
research Androgenetic Alopecia: Pathogenesis and Potential for Therapy
Hair loss needs more research for better treatments.
research The Effects of Estrogens on Linear Bone Growth
Oestrogens are key for bone growth during puberty in both boys and girls.