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S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Stress can worsen skin conditions by affecting hormone levels and immune response.

Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Testosterone may slow down wound healing and increase inflammation.

5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Zinc supplements can resolve skin issues caused by zinc deficiency.

Some medications can cause acne, and stopping these drugs is the main treatment.

Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.

The document concludes with guidance for doctors on diagnosing and treating hirsutism effectively and safely.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

Hormonal therapies are safe and effective for treating adult women's acne.

A blood pressure drug, diltiazem, may also help treat influenza.

The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Bee venom might be a good alternative treatment for various skin conditions because it has many healing properties.

Nanoemulsion-based drug delivery systems are versatile and have potential for treating various medical conditions and improving vaccines.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Geranium sibiricum extract helps hair grow and is more effective than minoxidil but can be toxic in high concentrations.