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Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.

Blocking 11β-HSD1 can lessen the harmful effects of glucocorticoids on hair growth cells.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

Nonclassic adrenal hyperplasia is a genetic condition that can cause early puberty and fertility problems, treated with specific steroids.

SAHA syndrome is a condition in women involving skin and hair issues, often related to hormonal imbalances, and is treated based on the underlying cause.

Skin problems are common in Lupus patients and can indicate the disease's severity, requiring specific treatments and lifestyle changes.

The document concluded that various dermatological treatments have different effectiveness and side effects, with some causing irritation, allergic reactions, or systemic effects.

Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

Norethisterone (jenapharm) therapy is effective for endometrial cancer.

Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Some dermatological medications can impair male fertility, so consult a doctor before trying to conceive.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.

Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

The document says that treating the root cause of hair follicle damage is crucial to prevent permanent hair loss, and treatment options vary.

Nutrients like vitamins, copper, zinc, and amino acids are crucial for healthy hair and wool growth.

The document concludes that treating female hair loss should target reducing excess androgen and blocking its effects on hair follicles, with the best treatments being hormonal therapy, adrenal suppression, and topical minoxidil.

Using rodents for research shows that health problems in the womb can cause diseases later in life.

Tianeptine, an antidepressant, may prevent stress-induced hair loss in mice.

Polycystic Ovary Syndrome (PCOS) often leads to severe acne, and lifestyle changes and hormonal treatments can help manage it.

Hormonal therapy is effective for treating acne in adult women, especially with signs of high androgen levels.

Hormonal therapies are effective for managing hair and skin symptoms in women with PCOS.

Excess androgens may cause PCOS, not just be a symptom.

Dogs with dermatomyositis, especially Collies and Shetland Sheepdogs, need better treatments for their skin and muscle inflammation.