January 2020 in “Der Pharmacia Lettre” This review discusses natural remedies and nanoparticle formulations for alopecia management and reports no new clinical results, emphasizing potential benefits of herbal treatments over synthetic therapies.
3 citations
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November 2025 in “Biomimetics” This review discusses the potential of hydrogel-based interventions for radiation-induced skin injury, providing no new clinical results but highlighting their synergistic mechanisms and promise in improving treatment strategies.
December 2020 in “مجله كليه طب الكندي” This review discusses various types and causes of alopecia, highlights the limitations of synthetic treatments, and suggests that naturally occurring drugs may offer safer management options; it reports no new clinical results.
February 2020 in “Our Dermatology Online” A synthetic drug and a South American herb may help treat alopecia areata in Chinese men.
11 citations
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May 2018 in “Philosophical Transactions of the Royal Society B” This review covers recent developments in materials for in vitro and in vivo stem cell manipulation, highlighting innovative substrate properties but does not report new experimental results.
1 citations
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July 2021 in “Forensic science international” This study found that segmental single hair analysis produced ocfentanil concentration profiles similar to those from hair lock analysis, supporting its use in cases with limited samples.
November 2025 in “Medical alphabet” This study highlights that physiotherapeutic methods like low-intensity laser therapy, radiofrequency, and electrical stimulation show promising effectiveness in stimulating hair growth and treating telogen effluvium by enhancing cell activity, ATP synthesis, and transdermal drug delivery.
25 citations
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July 2019 in “Experimental Dermatology” This review discusses the role of cholesterol homeostasis in hair follicle biology and its potential connections to various hair disorders, but it reports no new findings.
40 citations
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January 2016 in “Elsevier eBooks” This article explains the structure and multifunctional roles of the human skin, including its protective, regulatory, and sensory functions, but does not report new research findings.
June 2021 in “Psychiatria Danubina” The antidepressant escitalopram likely caused hair loss in a patient.
This article reviews different generations of synthetic retinoids for dermatological use, discussing their efficacy and significant side effects, but reports no new clinical results.
2 citations
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March 2010 in “Acta Biochimica Polonica” This study observed that conjugates of the anticancer drug raltitrexed with dextran and albumin were more cytotoxic than the free drug at high concentrations, altering cell cycle effects.
88 citations
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February 2008 in “Journal of Medicinal Chemistry” Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.
This review explores the synthesis and potential of azasteroids as novel drugs, discussing challenges in their production and reporting no new clinical results.
9 citations
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November 2004 in “Bioorganic & Medicinal Chemistry Letters” This study identified potent dual inhibitors of 5α-reductases 1 and 2 that may aid in designing new drugs for related diseases.
November 2021 in “Pharmaceutical Sciences” This study found that the compound androstane-17-carboxamide 6 may serve as a lead for new drugs to treat BPH and prostate cancer by reducing the weight of androgen-dependent glands.
54 citations
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March 2024 in “Journal of Medicinal Chemistry” This article summarizes the properties, synthesis, and biomedical applications of molecules with N-oxide functionalities, emphasizing their growing role in healthcare due to their unique properties, such as water solubility and redox reactivity, crucial for drug targeting and cytotoxicity.
11 citations
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June 2016 in “European Journal of Medicinal Chemistry” This study found that two synthesized androst-4-ene-3-one derivatives, 6f and 6g, exhibited stronger anti-proliferative effects than common drugs on prostate cancer cell lines, with low toxicity to rat cells.
October 2024 in “International Journal of Pharmaceutics” This study aimed to develop a new transdermal patch for treating androgenetic alopecia using finasteride, combined with chemical permeation enhancers to improve drug delivery through the skin, but results of pharmacokinetics and pharmacodynamics evaluations are not reported.
January 2023 in “IntechOpen eBooks” This chapter reviews various synthetic methods for creating pharmacologically active diazines, particularly focusing on pyrimidines, and discusses their potential in clinical applications. It also examines novel synthetic strategies that improve the drug-like qualities and safety profiles of these compounds.
2 citations
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November 2017 in “Food Additives & Contaminants: Part A” This study developed a validated method to detect prohibited drugs in dietary supplements, finding minoxidil, triaminodil, and finasteride in some samples.
3 citations
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August 2017 in “Synlett” This study reports a novel method for synthesizing substituted hydantoins, including the anticonvulsant drug ethotoin, using safer reagents and fewer steps compared to conventional protocols.
11 citations
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April 2021 in “Advanced synthesis & catalysis” This study reports that the dye peri-xanthenoxanthene (PXX) can act as an efficient photocatalyst for various radical reactions, including complex dual catalytic processes and the synthesis of an investigational drug intermediate.
7 citations
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December 2021 in “Annals of Phytomedicine An International Journal” This study observed that silver nanoparticles synthesized using Laurus nobilis leaf extracts significantly inhibited protein denaturation and membrane stabilization in vitro, suggesting potential as a basis for novel antiarthritic drugs.
January 2016 in “Graduate Medical Education Research Journal” This study identified AH01 derivatives and related compounds with high antischistosomal efficacy and reduced antiandrogenic effects, suggesting potential new directions for schistosomiasis drug development.
This study found that four synthesized thiazolidinone derivatives showed potential anticancer activity against MCF7 and HeLa cell lines, suggesting their further investigation for anticancer drug development.
8 citations
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June 2017 in “Steroids” This study evaluated novel steroid compounds for their ability to inhibit 5α-reductase, showing that compound 16a significantly reduced rat prostate weight more than epristeride and exhibited excellent in vitro inhibitory potency, indicating its potential as a lead candidate for further benign prostatic hyperplasia drug research.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This guide explores the fundamental science and practical applications of nanocrystal technologies to enhance the bioavailability of poorly water-soluble drugs, detailing synthesis methods, stability solutions, and drug delivery innovations like hydrogel composites and microneedle platforms.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This comprehensive guide from nanotechsci.com explores how nanocrystal technology enhances the bioavailability of poorly water-soluble pharmaceuticals, detailing the science behind crystallization and practical synthesis techniques, and discussing their advanced drug delivery applications across various routes.
April 2024 in “International Journal of Advanced Research in Science Communication and Technology” This review explores the impact of synthetic and herbal drugs on hormone levels and ovarian tissue in PCOD but reports no new clinical findings.