research Androgen Receptor Ligands: Agonists and Antagonists
Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.
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research Therapeutic Anti-Inflammatory Potential of Formyl-Peptide Receptor Agonists
Formyl-peptide receptor agonists could be new anti-inflammatory drugs.
research Quantification of the Vitamin D Receptor-Coregulator Interaction
Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.
research TRPV3 Ion Channel: From Gene to Pharmacology
The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.
research Peroxisome Proliferator-Activated Receptors (PPARs) and PPAR Agonists: The Future in Dermatology Therapeutics?
PPAR agonists show promise for skin conditions but need more research before being a main treatment.
research Olfactory Receptor OR2AT4 Regulates Human Hair Growth
A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.
research PPAR-γ Signaling as a Key Mediator of Human Hair Follicle Physiology and Pathology
PPAR-γ is important for healthy hair and its problems, and more research on PPAR-γ treatments is needed.
research Activation of Transient Receptor Potential Vanilloid-3 Inhibits Human Hair Growth
Activating TRPV3 stops human hair growth.
research Topical L-Thyroxine: The Cinderella Among Hormones Waiting to Dance on the Floor of Dermatological Therapy?
Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.
research Understanding the Role of Prostaglandin E2 in Regulating Human Platelet Activity in Health and Disease
Prostaglandin E2 affects human platelet activity in complex ways that could lead to personalized heart disease treatments.
research Sequence-Structure Based Phylogeny of GPCR Class A Rhodopsin Receptors
The research found how GPCR Class A Rhodopsin receptors are related and suggested possible substances they interact with.
research Therapeutic Strategies for Treating Hair Loss
The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.
research Chemicals and Stem Cells in the Promotion of Regeneration
Chemicals and stem cells combined have advanced regenerative medicine with few safety concerns, focusing on improving techniques and treatment effectiveness.
research Evaluation of a Pool of Biomimetic Peptides on Human Hair Follicles: A Preclinical Study
Biomimetic peptides were found to promote hair growth and prolong the growth phase in human hair follicles.
research Cannabinoid Signaling in the Skin: Therapeutic Potential of the Cutaneous Cannabinoid System
Cannabinoids may help treat various skin conditions.
research Activation of TRPV3 Regulates Inflammatory Actions of Human Epidermal Keratinocytes
TRPV3 in skin cells causes inflammation and cell death.
research Calcitonin Gene-Related Peptide (CGRP) May Award Relative Protection from Interferon-γ-Induced Collapse of Human Hair Follicle Immune Privilege
CGRP may help protect hair follicles from immune system attacks, potentially slowing hair loss.
research Human Hair Follicles Can Smell: OR2AT4-Mediated Hair Growth Regulation
Human hair follicles have a scent receptor that can influence hair growth.
research Historical and Current Adenosine Receptor Agonists in Preclinical and Clinical Development
The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.
research Cannabinoids: Current and Future Options to Treat Chronic and Chemotherapy-Induced Neuropathic Pain
Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.
research Retinoid-Mediated Stimulation of Steroid Sulfatase Activity in Myeloid Leukemic Cell Lines Requires RARα and RXR and Involves the Phosphoinositide 3-Kinase and ERK-MAP Kinase Pathways
Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.
research STAT5 Activation in the Dermal Papilla Is Important for Hair Follicle Growth Phase Induction, Hair Follicle Regeneration, and Wound Healing
Activating STAT5 in the skin's dermal papilla is key for starting hair growth, regenerating hair follicles, and healing wounds.
research The Adenosine-Generating Ecto-Enzyme CD73 Regulates Human Hair Growth
The enzyme CD73 helps control human hair growth and could be targeted to treat hair growth disorders.
research Chemokine Receptor CCR5 as a Novel Target for the Treatment of Alopecia Areata
Blocking the CCR5 receptor may be a new way to treat hair loss from alopecia areata.
research MicroRNA-214 Controls Skin and Hair Follicle Development by Modulating the Activity of the Wnt Pathway
MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.
research The Endocannabinoid System of the Skin: A Potential Approach for the Treatment of Skin Disorders
Targeting the skin's endocannabinoid system could help treat skin disorders.
research Chrousos Syndrome: From Molecular Pathogenesis to Therapeutic Management
The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.
research Treatment of Hyperandrogenism in Women
Cyproterone acetate is the preferred treatment for women's hyperandrogenism when estrogen/progestogen use is safe.
research Adipose-Derived Stem/Stromal Cells in Regenerative Medicine
Fat tissue stem cells show promise for repairing different body tissues and are being tested in clinical trials.
research Non-Endocrine Alopecia in Dogs and Cats: Conditions, Treatments, and Prognoses
The document concludes that non-endocrine alopecia in pets varies in treatment effectiveness and often has a poor prognosis, especially in cats.