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5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

JAGGED1 could help regenerate tissues for bone loss and heart damage if delivered correctly.

The study found that women with hyperandrogenic PCOS have higher levels of AKT1 and AKT2 proteins in their cells, which may lead to cell dysfunction.

The document discusses various eye conditions and their treatments, including a rare eye cancer in a baby, vision loss from a cancer drug, cataracts from a baldness treatment, a rare skin disorder, and a specific type of eye disease diagnosed with a special imaging technique.

Finasteride, often used for hair loss, can potentially cause cataracts.

Multiple eye conditions were studied, highlighting the importance of various imaging methods for diagnosis, the vision side effects of drugs tamoxifen and Propecia, and the usefulness of optical coherence tomography for diagnosing and monitoring macular and retinal diseases.

Inhibiting ALOX12 can help hair cuticle maturation by increasing S100A3 citrullination.

A man with a birthmark on his scalp developed hair loss that improved with treatment, but the link between the birthmark and hair loss was unclear.

Autism's genetics are linked with early age of puberty and less hair loss, but not with hormone levels or polycystic ovary syndrome.

Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

Melanoma risk tools need improvement, certain gene mutations cause skin diseases and could be treated by targeting those mutations, skin wrinkling may relate to lung aging due to genetic factors, and oxidative stress affects hair loss but can be reduced in low oxygen.

Protease Nexin-1 is found in human hair growth cells and is affected by male hormones.

The protein aPKCλ is crucial for keeping hair follicle stem cells inactive and for hair growth and regeneration.

The research shows that a gene called Wnt3 affects hair growth and structure, causing short hair and balding when overactive.

BAY 43-9006 helps control kidney cancer growth but doesn't significantly increase overall survival.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.

New treatments for immune disorders caused by FOXN1 deficiency are promising.

Pannexin 3 is important for bone formation and the development of bone cells.

The document concludes that using specific tools and tests is essential for identifying the cause of hair loss and deciding on the right treatment.

Mesenchymal stromal cells may help treat severe COVID-19, but more research is needed to confirm their effectiveness.

Heparin and protamine are promising in tissue repair and organ regeneration, including skin and hair.

Doctors should use a detailed patient history and physical exam to diagnose joint pain, and consult a rheumatologist early for suspected autoimmune diseases.

Damaged hair follicles make mice more prone to skin inflammation and skin cancer after UV exposure.