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210-240 / 953 resultsresearch The importance of the neuro‐immuno‐cutaneous system on human skin equivalent design
This review explores the interactions between the skin, peripheral nervous system, and immune system and reports no new results; the authors highlight the importance of understanding these connections for various skin conditions.
research The Skin and Inflamm-Aging
This review explores the role of aging-related changes in skin, discussing how impaired skin barrier function may contribute to systemic inflammation, or "inflamm-aging," which in turn could impact the broader decline in organ and tissue function seen in aged individuals.
research Comparative advantage and efficacy of natural products for polycystic ovary syndrome
This study focused on categorizing the research status of natural products for improving ovary and uterus quality, fertility, and weight loss in PCOS, but noted a lack of continuous studies connecting basic research to clinical trials.
research The Multiple Consequences of Obesity
This chapter reviews the diverse and interrelated consequences of obesity on physical, metabolic, reproductive, psychosocial, and economic health without reporting any new clinical results.
research The brain–gut–skin axis in inflammatory and disfiguring skin diseases: mechanistic insights, clinical correlations, and therapeutic strategies
This review highlights the role of the brain–gut–skin axis in systemic inflammatory skin conditions, revealing potential interventions like microbiome-directed treatments and integrative therapies, though emphasizes the need for more robust clinical validation.
research Melanocytes in regenerative medicine applications and disease modeling
This review highlights the diverse roles of melanocytes in pigmentation, immunity, and hearing among other functions, their involvement in disorders, and their emerging potential in regenerative medicine, including applications in disease modeling and therapy development using advanced technologies.
research Hair Follicle Stem Cells and Hair Regeneration
research Polycystic Ovary Syndrome: Etiology, Current Management, and Future Therapeutics
This review discusses various potential risk factors and possible therapeutic interventions for polycystic ovary syndrome, including the modulation of gut microbiota, but reports no new findings.
research Recent advances in the role of neuroregulation in skin wound healing
This review highlights the critical role of neuroregulation in skin wound healing, emphasizing how neurotransmitters and neuropeptides regulate inflammation, angiogenesis, and cell proliferation, and discusses potential therapeutic strategies, such as neuromodulation, to enhance these processes.
research Innovative Functional Biomaterials as Therapeutic Wound Dressings for Chronic Diabetic Foot Ulcers
This review examines the potential of biomaterial-based wound dressings in managing diabetic foot ulcers, highlighting their versatility and therapeutic properties for promoting wound healing in individuals with diabetes mellitus.
research Clinical Conditions Targeted by OnabotulinumtoxinA in Different Ways in Medicine
This opinion article reviews various pathways through which onabotulinumtoxinA might work in medical treatments, highlighting applications beyond muscle paralysis, including pain inhibition and potential effects on hair loss and cancer cell apoptosis.
research Anxiety and Depression in Women with Polycystic Ovary Syndrome
This study found that women with PCOS in Poland had higher anxiety and depression levels and lower ego-resiliency compared to healthy women, often using passive stress-coping strategies.
research Role of Phenylalanine and Its Metabolites in Health and Neurological Disorders
This review discusses the potential antidepressant effects of phenylalanine, highlighting its significant activity in laboratory studies, but reports no new clinical findings.
research Alpinetin promotes hair regeneration via activating hair follicle stem cells
This study found that Alpinetin, applied topically in C57BL/6J mice, promoted hair regeneration by activating hair follicle stem cells through Wnt signaling, extending the anagen phase and increasing hair shaft length, with no cytotoxicity observed in keratinocytes and fibroblasts.
research Neurotoxins Acting at Synaptic Sites: A Brief Review on Mechanisms and Clinical Applications
This review discusses the structural properties, pharmacological effects, and clinical applications of neurotoxins on synapses, reporting no new experimental results.
research SARS-CoV-2 Infection and Alpha-Synucleinopathies: Potential Links and Underlying Mechanisms
This review explores whether SARS-CoV-2 could trigger or worsen α-synucleinopathies, like Parkinson's disease, by affecting α-synuclein misfolding and aggregation, potentially linking COVID-19 with the development of parkinsonism-like symptoms.
research Prostaglandins: Key players in immunomodulation of the nervous system
This review discusses the roles of prostaglandins in the nervous system and their therapeutic potential for neurological diseases, noting their complex interactions with immune cells and signaling pathways.
research Hair Follicle Stem Cells and Hair Regeneration
research Exercise in the management of polycystic ovary syndrome: A position statement from Exercise and Sports Science Australia
This position statement reviews the role of exercise professionals in managing PCOS and provides recommendations for physical activity, but it reports no new clinical findings.
research Essential Oils and Melatonin as Functional Ingredients in Dogs
This review discusses the potential use of essential oils and melatonin as nutraceuticals in dogs, highlighting their promising applications for addressing conditions like stress, anxiety, sleep disorders, and alopecia.
research Steroid Responsive Mononeuritis Multiplex in the Cronkhite–Canada Syndrome
In this case report, a patient with Cronkhite-Canada syndrome also had mononeuritis multiplex, and the authors suggest that an autoimmune mechanism may be involved based on steroid responsiveness and electrophysiological findings.
research The Skin Microenvironment: A Dynamic Regulator of Hair Follicle Development, Cycling and Disease
This review analyzed the complex interactions within the skin microenvironment that influence hair follicle development and regeneration, exploring its role in hair-related disease treatment and highlighting research challenges and future directions.
research Ganoderma lucidum extract attenuates corticotropin-releasing hormone induced cellular senescence in human hair follicle cells
Ganoderma lucidum extract may help treat stress-related hair loss.
research Brown adipose tissue in the form of innovative approach for polycystic ovary syndrome treatmentstill long time to reach clinical arena: a narrative review
This review discusses the potential role of brown adipose tissue in managing polycystic ovary syndrome and reports no new clinical results; it highlights a need for further research on this therapeutic avenue.
research Referee report. For: Hair greying in castrated mice [version 1; peer review: 1 approved with reservations]
This study found that hair plucking induced greying in castrated mice, suggesting that decreased androgen levels could play a role in age-related hair greying in humans.
research Hair greying in castrated mice
This study found that hair plucking via waxing led to greying of hair in castrated mice, suggesting that decreased androgen levels may contribute to age-related hair greying in humans.
research Strength and Tenderness: Fibronectin Joins Hair Follicle Stem Cell Niche
Fibronectin is essential for hair follicle regeneration and may help rejuvenate aged skin.
research A Systematic Scoping Review and Conceptual Analysis of New-Onset Fibromyalgia Manifestations After Non-Hospitalized COVID-19: Empirics, Definitions, Methodologies, Pathophysiology, Mapping of Literature, and Knowledge Gaps
This scoping review reports that while empirical evidence suggests an overlap between Long/Post Covid-19 syndrome, chronic fatigue syndrome, and fibromyalgia, the underlying molecular mechanisms remain unclear, highlighting the need for standardized definitions and rigorous methodologies in Long Covid research.
research Polycystic ovary syndrome (PCOS), an inflammatory, systemic, lifestyle endocrinopathy
This review discusses polycystic ovary syndrome, its detection, and treatments, concluding that lifestyle changes may offer sustainable management, although it reports no new clinical results.