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The protein EZH2 blocks microRNA-22, increasing STK40 protein, which helps hair follicle stem cells change and grow hair.

The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.

Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.

Epidermal stem cells show promise for treating orthopedic injuries and diseases.

Thyroid problems can cause hair loss and change hair texture.

Hidradenitis Suppurativa has genetic links, with certain gene mutations more common in patients and a third of cases having a family history.

Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.

Key genes crucial for sheep hair follicle development were identified, aiding fine wool breeding and human hair loss research.

New research shows that skin diversity is influenced by different types of dermal fibroblasts and their development, especially involving the Wnt/β-catenin pathway.

The research identifies genes linked to wool quality in sheep and provides insights to improve wool production.

Androgenetic alopecia, or hair loss, is caused by a mix of genetics, hormones, and environment, where testosterone affects hair growth and causes hair to become smaller and grow for a shorter time.

Researchers found genes linked to hair growth cycles in Inner Mongolia cashmere goats, which could help understand and treat hair loss.

Certain genes and pathways are linked to the production of finer and denser wool in Hetian sheep.

Human skin can be reconnected to nerves using stem cells, which may help with skin health and healing.

Eating fewer calories may slow skin aging and improve skin health through various biological changes.

Wnt/β-catenin signaling is important for keeping skin cell attachment structures stable.

Zinc is crucial for skin health and treating various skin disorders.

Keratin protein production in cells is controlled by a complex system that changes with cell type, health, and conditions like injury or cancer.

Functional foods can improve hair and skin health.

Choosing the right method to separate skin layers is key for good skin cell research.

Key proteins and pathways regulate wool fiber diameter in Alpine Merino sheep.

Scientists are still unsure what triggers the immune system to attack hair follicles in Alopecia areata.

The document concludes that while some organisms can regenerate body parts, mammals generally cannot, and cancer progression is complex, involving mutations rather than a strict stem cell hierarchy.

Human hair follicles may provide a noninvasive way to diagnose diseases and have potential in regenerative medicine.

PI3K/Akt pathway is crucial for hair growth and regeneration.

Adding insulin-like growth factor 1 and bone marrow-derived stem cells to a collagen-chitosan scaffold helps wounds heal faster and regrows hair follicles.

Nanotechnology could improve hair regrowth but faces challenges like complexity and safety concerns.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.

Mouse hair follicle stem cells lose their ability to change into different cell types after being grown for a long time.