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This review discusses the advantages and properties of mucoadhesive buccal dosage forms and reports no new clinical findings; the authors emphasize the potential of spanlastics as flexible, biodegradable drug carriers.

This review highlights recent developments in nanovesicular carriers for enhancing molecule delivery into and across the skin, focusing on the design and evolution of phospholipid and non-phospholipid systems used in cosmetics and treating various skin conditions.

This review highlights the potential of spanlastics, a new type of drug delivery system, to enhance drug administration by offering better deformability and stability compared to other nanocarriers, potentially improving targeted drug delivery across various applications.

This study evaluated green tea extract-loaded spanlastic formulations and found that a vesicle builder to edge activator ratio of 8:2 produced optimal characteristics, including a particle size of 419.70 nm, an entrapment efficiency of 60.85%, and a drug loading of 11.07%.

This review highlights that transferosomes, or ultradeformable lipids, show promise for improving dermal delivery, exhibiting efficient drug transport across the skin's barrier and offering potential benefits for treating chronic skin disorders with better bioavailability.

This study optimized efinaconazole spanlastic nanovesicles using risk management and multivariate analysis for potential transungual delivery to treat onychomycosis, achieving improved drug permeability and dissolution efficiency.

This study found that co-delivery of minoxidil and caffeine in transfersomes with an optimized polysorbate formulation enhanced hair length and weight in vivo.

This study reported that meloxicam-loaded spanlastics, created using the ethanol injection method, demonstrated potential as a drug delivery system with sustained release and effective entrapment efficiency.

This study found that Transcutol P significantly enhanced the skin penetration of Finasteride in vitro, while cationic and anionic surfactants did not show such effects.

This review discusses various nanoparticles used to enhance skin permeation and target delivery to skin organelles, but reports no new experimental results.

This review discusses various nanotechnology-based strategies for managing melasma and reports no new clinical results, highlighting the potential of innovative drug delivery systems in treating hyperpigmentation.

In this study, desmopressin-loaded elastic liposomes (ODEL1) showed improved permeation and drug deposition across rat skin by altering the skin's cohesive energies and causing reversible changes on its surface.

This review reports on recent surfactant-based niosome formulations, including those with polysaccharides, for versatile drug delivery applications such as ocular, oral, and transdermal settings, while discussing their limitations and potential prospects.

This study found that using spanlastics, a nano, surfactant-based drug delivery system, improved the bioavailability, drug release characteristics, and pharmacokinetic behavior of famotidine, a poorly soluble drug, by enhancing its dissolution and membrane permeation.

This study found that the combination of letrozole and quercetin loaded in spanlastics showed enhanced cytotoxicity and other anticancer effects against MCF-7 breast cancer cells compared to individual treatments.

This review discusses the applications and challenges of lipid nanosystems in various fields, comparing techniques for evaluating nanoparticle properties, and reports no new experimental results.

This study investigated spanlastic nanovascular drug delivery systems and found that they can effectively enhance the transport and continuous release of medicines with small particle size, low polydispersity index, and satisfactory entrapment efficiency, showing potential as carriers for drug delivery.

This study investigated a new formula called SV-loaded nanospanlastics for topical application to treat androgenic alopecia. It showed similar effectiveness to minoxidil lotion but with fewer adverse effects when used to enhance dermal delivery and efficacy of sodium valproate.

This study found that transethosomal gel loaded with propranolol hydrochloride prolonged drug release and increased peak plasma concentration compared to an oral tablet, suggesting a promising alternative for delivery.

This review discusses various strategies to enhance drug delivery through the skin barrier, highlighting liposomes as promising carriers for increased dermal concentrations in topical therapies, but reports no new research results.

This article explains the preparation methods and applications for various vesicle and particle systems used in transdermal drug delivery, highlighting their effectiveness and potential for further development in this field.

This study found that a topical transethosomal system may enhance the skin penetration and deposition of naftifine compared to a marketed cream, potentially overcoming the stratum corneum barrier.

In this study, researchers explained that healing of extensive skin defects involves granulation filling the wound cavity, followed by epithelialization from skin edges and hair follicles, which are crucial steps in wound healing.

This review discusses various nanoparticles and nanoemulsions being investigated for transdermal drug delivery and reports no clinical results; it highlights potential applications in treating alopecia, wound healing, psoriasis, and melanoma.

This study found that penetration enhancer-containing vesicles significantly improved minoxidil delivery to the skin compared to traditional liposomes and penetration enhancer-containing ethanolic solutions, with deformability linked to enhanced deposition.

This study found that nobiletin-loaded vesicles effectively restored skin condition in a mouse model of skin cancer, suggesting they are a promising treatment delivery system.

In this study, researchers reviewed recent advances in using nanoencapsulation technology to improve the pharmacological treatment of alopecia, suggesting its potential to enhance drug delivery and reduce adverse effects compared to conventional methods.

This review discusses the pharmacological actions of mangiferin and the potential of delivery carriers to overcome its limitations, but reports no new clinical results.

This study found that nano-transferosomal gel formulations of finasteride improved its delivery across skin layers, potentially reducing major side effects associated with oral administration for treating male pattern baldness.

This review discusses the potential of nanotechnology-based formulations for delivering topical minoxidil to improve hair loss treatment outcomes and reports no new clinical results, urging further research into their benefits and safety considerations.