64 citations,
April 2005 in “Journal of Investigative Dermatology” Topical oligonucleotide therapy targets hair follicles effectively.
15 citations,
September 2007 in “Cell & tissue research/Cell and tissue research” Embryonic and adult stem cells are valuable for improving skin grafts and cell therapy.
2 citations,
September 2018 in “Tissue Engineering Part A” Xeno-free three-dimensional stem cell masses are safe and effective for improving blood flow and tissue repair in limb ischemia.
[object Object] 21 citations,
January 2018 in “Journal of Investigative Dermatology” Rats can't grow new hair follicles after skin wounds, unlike mice, due to differences in gene expression and response to WNT signaling.
20 citations,
September 2018 in “Journal of colloid and interface science” Modified keratin binds better to hair, especially bleached hair.
4 citations,
January 2018 in “Advances in Experimental Medicine and Biology” The document concludes that hair follicles have a complex environment and our understanding of it is growing, but there are limitations when applying animal study findings to humans.
36 citations,
August 2011 in “Journal of dermatological science” Human hair has a protective lipid layer that can be damaged by moisture and treatments, affecting hair growth and health.
November 2017 in “Elsevier eBooks” PCOS is a genetic disorder affecting women's reproductive health, with treatments focused on symptoms like insulin resistance and fertility.
July 2024 in “Pharmaceutics” The new hydrogel treatment promotes faster hair growth and better skin health for hair loss.
December 2015 in “JAMA Dermatology” Dermatologists can help diagnose endocrine disorders like PCOS and metabolic syndrome by looking at skin symptoms.
10 citations,
January 2012 in “Journal of biomedical optics” Melanin density affects hair color, and this method can help in cosmetic assessments and diagnosing hair diseases.
42 citations,
July 2015 in “Cosmetics” Nanotechnology improves hair care products by enhancing ingredient stability, targeting treatment, and reducing side effects, but more research on its toxicity is needed.
202 citations,
June 2005 in “Aaps Pharmscitech” Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.
7 citations,
January 2001 in “PharmacoEconomics” The article concludes that a balance is needed between individual healthcare needs and societal resources when it comes to lifestyle drugs, with a call for compassionate policy application.
December 2023 in “Frontiers in pharmacology” Progesterone initially worsens but later reduces neuropathic pain in mice, through different mechanisms.
7 citations,
August 2021 in “Pharmaceutics” Freeze-dried dexamethasone nanoparticles in a hydrogel are stable and effective for treating alopecia areata.
77 citations,
July 2013 in “Best Practice & Research in Clinical Obstetrics & Gynaecology” Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.
6 citations,
July 2017 in “Clinics in Plastic Surgery” The document concludes that individualized reconstruction plans are essential for improving function and appearance after head and neck burns.
11 citations,
August 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” A gene mutation causes early keratinocyte maturation leading to hair loss in Olmsted syndrome.
November 2022 in “Cosmetics” Red pigmented rice, like Sang-Yod rice, could help promote hair growth and prevent hair loss.
5 citations,
April 2022 in “IntechOpen eBooks” Nanoemulgel is a better way to deliver drugs through the skin for various conditions.
188 citations,
October 2012 in “The AAPS Journal” The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.
77 citations,
July 2020 in “Journal of the European Academy of Dermatology and Venereology” Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.
The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.
288 citations,
June 2009 in “Human reproduction update” The modified Ferriman-Gallwey method is a useful tool for diagnosing hirsutism.
35 citations,
August 2009 in “Differentiation” Desmoglein 4 is controlled by specific proteins that affect hair growth.
6 citations,
May 2022 in “Pharmaceutics” Zinc pyrithione dissolves quickly on the skin and in hair follicles, especially in smaller particles.
122 citations,
April 2011 in “European Journal of Pharmaceutics and Biopharmaceutics” Particles around 100 nm can penetrate and stay in hair follicles without passing through healthy skin, making them safe for use in topical products and useful for targeted drug delivery.
[object Object] 39 citations,
October 2012 in “Familial cancer” New therapies for Birt–Hogg–Dubé syndrome are being developed based on understanding the FLCN gene's role.
83 citations,
July 2008 in “Current Opinion in Chemical Biology” The document concludes that understanding sulfation biology is crucial for creating treatments due to its importance in biological functions and disease.