research Mechanism of TAp73 Inhibition by ΔNp63 and Structural Basis of p63/p73 Hetero-Tetramerization
ΔNp63α stops TAp73β from working in skin cancer by blocking its access to specific genes, not by directly interacting with it.
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research Microneedles Mediated Bioinspired Lipid Nanocarriers for Targeted Treatment of Alopecia
A new hair loss treatment uses tiny needles to deliver a drug-loaded lipid carrier, promoting hair growth more effectively than current treatments.
research Inducing Hair Follicle Neogenesis with Secreted Proteins Enriched in Embryonic Skin
Three specific proteins can turn adult skin cells into hair-growing cells, suggesting a new hair loss treatment.
research Androgen Antagonists in Androgen Target Tissues
Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.
research Iontophoresis of Minoxidil Sulphate Loaded Microparticles: A Strategy for Follicular Drug Targeting?
Iontophoresis improves minoxidil delivery to hair follicles for hair loss treatment.
research Hairline Design in Hair Replacement Surgery
Dr. Michael Beehner recommends a personalized, careful approach to hairline design in hair replacement surgery for a natural look.
research A Method to Improve the Efficacy of Topical Eflornithine Hydrochloride Cream
Using microneedles before applying eflornithine cream can make it more effective at stopping hair growth.
research Group IID, IIE, IIF, and III Secreted Phospholipase A2s
Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.
research Effectiveness of a Layer-by-Layer Microbubbles-Based Delivery System for Applying Minoxidil to Enhance Hair Growth
Minoxidil-coated microbubbles with sonication effectively enhance hair growth.
research Multifunctional Merkel Cells: Their Roles in Electromagnetic Reception, Fingerprint Formation, Reiki, Epigenetic Inheritance, and Hair Form
Merkel cells may have roles in sensing magnetic fields, creating fingerprints, Reiki energy healing, passing on environmental information to offspring, and influencing hair shape.
research Physical Methods for Topical Skin Drug Delivery: Concepts and Applications
New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.
research A Portable Electrospinner for Nanofiber Synthesis and Its Application for Cosmetic Treatment of Alopecia
A portable device can create nanofibers to improve the appearance of thinning hair better than commercial products.
research A Novel and Safe Small Molecule Enhances Hair Follicle Regeneration by Facilitating Metabolic Reprogramming
Small molecule IM boosts hair growth by changing stem cell metabolism.
research Adaptive Gelatin Microspheres Enhanced Stem Cell Delivery and Integration With Diabetic Wounds to Activate Skin Tissue Regeneration
Gelatin microspheres with stem cells speed up healing in diabetic wounds.
research A Regulatory Perspective on Pharmacokinetic/Pharmacodynamic Modelling
The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.
research Reconstruction of the Scalp, Calvarium, and Frontal Sinus
The document concludes that careful surgical methods and choosing the right materials are key for successful scalp, skull, and frontal sinus reconstruction.
research A Fibrous Hybrid Patch Couples Cell-Derived Matrix and Poly(L-Lactide-Co-Caprolactone) for Endothelial Cells Delivery and Skin Wound Repair
The new patch made of cell matrix and a polymer improves wound healing and supports blood vessel growth.
research Application of Amber Filler for Production of Novel Polyamide Composite Fiber
Adding amber particles to polyamide fibers makes them suitable for medical textiles like compression socks.
research Effects on Steroid 5-Alpha Reductase Gene Expression of Thai Rice Bran Extracts and Molecular Dynamics Study on SRD5A2
Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.
research Advanced Medical Therapies in the Management of Non-Scarring Alopecia: Areata and Androgenic Alopecia
Advanced therapies like gene, cell, and tissue engineering show promise for hair regrowth in alopecia, but their safety and effectiveness need more verification.
research Structure Optimization of Tetrahydropyridoindole-Based Aldose Reductase Inhibitors Improved Their Efficacy and Selectivity
Optimizing the structure of a specific compound greatly improved its effectiveness and precision for treating diabetic complications.
research Novel Iron Oxide Nanocarriers Loading Finasteride or Dutasteride: Enhanced Skin Penetration for Topical Treatment of Alopecia
Iron oxide nanoparticles improve skin penetration and drug release for hair loss treatment.
research Neurotrophin-4 Modulates the Mechanotransducer Cav3.2 T-Type Calcium Current in Mice Down-Hair Neurons
Neurotrophin-4 increases calcium current in specific mouse neurons through the PI3K pathway.
research Exogenous Factors in Hair Disorders
Outside factors like grooming, chemicals, and the environment can damage hair and cause disorders.
research Simultaneous Determination of Androgens and Prostaglandins in Human Urine Using Ultra-High-Performance Liquid Chromatography–Tandem Mass Spectrometry
Researchers developed a reliable way to measure hormones in urine, showing that a baldness treatment doesn't change hormone levels.
research Development of Novel Indole-Based Bifunctional Aldose Reductase Inhibitors and Antioxidants as Promising Drugs for the Treatment of Diabetic Complications
New indole-based compounds, particularly cemtirestat, show promise as dual-function drugs for diabetic complications.
research LC-MS Bioanalytical Method for Simultaneous Determination of Latanoprost and Minoxidil in the Skin
Method measures latanoprost and minoxidil in skin accurately and precisely.
research Comprehensive Transcriptome Profiling of Balding and Non-Balding Scalps in Trichorhinophalangeal Syndrome Type I Patient
The study found genetic differences related to hair development that may explain hair loss in a patient with Trichorhinophalangeal syndrome type I.
research Morphological and Morphometric Study of the Androgenetic Alopecic Scalp Using Two- and Three-Dimensional Analysis Comparing Regional Differences
The study found that balding scalps have more thin hairs and larger oil glands, which might contribute to skin conditions related to hair loss.
research Combining Follicular Unit Extraction and Scalp Micropigmentation for the Cosmetic Treatment of Alopecias
FUE and SMP together can effectively treat hair loss, needing fewer procedures.