1 citations
,
November 2025 in “Clinical and Experimental Medicine” This review highlights the emerging role of long non-coding RNAs (lncRNAs) in dermatology, suggesting that lncRNAs significantly impact signaling pathways involved in normal skin functions and skin diseases, offering potential as biomarkers and therapeutic targets.
1 citations
,
September 2024 in “Jurnal Ilmiah JKA (Jurnal Kesehatan Aeromedika)” This study found that red galangal rhizome simplicia extract demonstrated the strongest antibacterial effect against Propionibacterium acnes among tested extracts, achieving a 31.5 mm inhibitory zone at a 20% concentration.
September 2025 in “Editora Pasteur eBooks” This abstract discusses the broad scope of dermatology and aesthetic procedures, highlighting their significant multidisciplinary evolution within the health sciences, but it does not report specific study results.
October 2023 in “Open Repository of the University of Porto (University of Porto)” Pharmacists play a crucial role in patient care and optimizing treatment outcomes.
68 citations
,
January 2013 in “BMC Pharmacology and Toxicology” This study found that glibenclamide exhibited a cytostatic effect on MDA-MB-231 breast cancer cells, potentially mediated through K ATP channels, and enhanced the antiproliferative impact of doxorubicin.
3 citations
,
January 2023 in “American journal of physiology. Cell physiology” This editorial reviews the roles and therapeutic potential of inward rectifying K+ channels in various physiological processes, highlighting their importance in health and disease but provides no new experimental results.
In this study, deer hair follicles were shown to be an effective in vitro bioassay model, demonstrating that K(ATP) channel modulators directly influence hair follicle growth through specific channel types.
28 citations
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August 2013 in “Hypertension” The authors concluded that diazoxide reduces undesirable side effects compared to minoxidil while increasing elastic fiber content and decreasing cell number in the aorta, suggesting potential suitability for treating vascular conditions with low arterial elastin and hypertension.
5 citations
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May 2022 in “Clinical & Experimental Metastasis” This study found that minoxidil and ranolazine, individually and in combination, reduced cellular invasiveness in hypoxic triple-negative breast cancer cell lines, suggesting potential anti-metastatic effects at clinically relevant doses.
2 citations
,
January 2019 in “Journal of Cosmetics, Dermatological Sciences and Applications” This study found that both a nutritional supplement and a topical hair lotion reduced hair loss and increased the anagen to telogen hair ratio in individuals with androgenetic alopecia.
80 citations
,
January 2020 in “Journal of Nanobiotechnology” This review highlights that incorporating nanomaterials into scaffolds can significantly enhance angiogenesis in tissue regeneration by simulating extracellular matrix structures and effectively delivering angiogenesis-related factors, offering promising designs for vascularization and therapeutic applications.
29 citations
,
February 2021 in “Cancers” This review discusses the role of ion channels in ovarian cancer progression and chemotherapy resistance, highlighting their potential as targets for diagnosis and treatment, but reports no new clinical results.
24 citations
,
April 2014 in “Oncotarget” This study found that minoxidil suppressed androgen receptor functions and stability, suggesting its potential use in treating diseases related to the androgen-AR pathway.
22 citations
,
March 2023 in “Bioengineering” This review discusses stem cell therapy as a promising treatment for epidermolysis bullosa, highlighting preliminary successes in treating skin lesions but noting the need for further research on effectiveness and safety.
9 citations
,
May 2025 in “Stem Cell Research & Therapy” This review discusses how extracellular vesicles play a dual role in age-related diseases by contributing to both disease pathogenesis and potential therapeutic strategies through the transfer of specific molecules.
January 2012 in “Journal of Investigative Dermatology” The document presented various studies on hair and cutaneous development, revealing insights into hair biology and potential therapeutic targets for hair-related conditions. Key findings included the role of stem cells and their niches in hair regeneration, the impact of TACE/ADAM17 depletion on alopecia, and the expression of somatostatin in hair follicles. Research on genetic factors, such as CYLD mutants and P-cadherin, highlighted their importance in hair growth and pigmentation. Studies on hair aging identified genes involved in hair loss in women over 40. Additionally, the potential of keratinocyte precursors from iPS cells for hair follicle regeneration and the effectiveness of a parathyroid hormone analog in reversing chemotherapy-induced alopecia were explored. The document also discussed the role of cholesterol biosynthesis in cicatricial alopecia, the necessity of Wnt signaling for hair follicle initiation, and the effects of ATP-sensitive potassium channel blockers on hair growth. These findings collectively advanced the understanding of hair growth, alopecia treatment, and skin regeneration.
March 2022 in “Molecules” This study found that adenosine promotes hair growth by stimulating the Wnt/β-catenin pathway in cultured human dermal papilla cells through activation of the adenosine receptor.
83 citations
,
December 2001 in “Journal of Investigative Dermatology” Minoxidil boosts hair growth by targeting adenosine and possibly sulfonylurea receptor 2B.
November 2010 in “Bradford Scholars (University of Bradford)” In this study, the authors reported that NNC55-9216, a selective SUR1 KATP channel opener, stimulated hair follicle growth in culture and enhanced the effects of minoxidil, suggesting a new potential treatment for hair loss.
1 citations
,
October 2023 in “Egyptian Journal of Immunology” This study found that women with PCOS had significantly higher levels of the pro-inflammatory chemokine MIP-1α compared to controls, suggesting an association with low-grade chronic inflammation, though the increase in MIP-1β levels did not reach statistical significance.
42 citations
,
July 2017 in “Molecular therapy” This study found that applying a tocotrienol-rich phytochemical topically induced hair follicle development in adult mice, revealing a new epidermal pathway involving E-cadherin and β-catenin.
28 citations
,
March 2007 in “E-Journal of Chemistry” This study found that a herbal hair oil containing 7.5% concentrations of specific plant extracts showed effective hair growth activity comparable to 2% minoxidil, with particularly promising results from oils prepared using the cloth pouch decoction method.
2 citations
,
September 2022 in “Indian Journal of Dermatology, Venereology and Leprology” This study identified common dermatological issues and procedures among transgender individuals in India, highlighting insufficient access to dermatological services and distinct cosmetic concerns related to hormone and surgery changes during transition.
2 citations
,
November 2021 in “International Journal of Current Pharmaceutical Research” This review discusses the pathogenesis, causes, and treatments of hirsutism but provides no new clinical findings; the authors emphasize the strong impact of hirsutism on quality of life.
2 citations
,
January 2017 in “Journal of Biotechnology Research Center” This study found that hair dyes significantly affect DNA sequence analysis, with the organic extraction method performing better on hair shafts and the prepFiler kit yielding higher success for follicle-included samples.
1 citations
,
September 2025 in “PLoS ONE” This study found that disrupted cholesterol homeostasis in scalp samples from cicatricial alopecia patients hinders hair regrowth by affecting hair follicle stem cell markers, with resulting effects confirmed in vitro and in animal models.
1 citations
,
January 2023 in “Elsevier eBooks” This review discusses the role of phospholipases in skin and hair health, suggesting that understanding their molecular control could inform new treatments for related conditions, but it presents no new clinical results.
1 citations
,
February 2020 in “International Surgery Journal” This study found that medical students have limited awareness and understanding of plastic surgery beyond cosmetic procedures, prompting the development of new educational modules to enhance their knowledge.
1 citations
,
November 2015 in “Journal of Evolution of Medical and Dental Sciences” This study observed that certain skin symptoms in SLE, such as malar rash and photosensitivity, are linked to systemic involvement, indicating their potential role as markers for disease activity.
March 2026 in “Dermatology Online Journal” Medicaid coverage for alopecia areata treatments is inconsistent and often limited.