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Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.

FA2H is essential for normal fur and sebum production in mice.

Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The document concludes that understanding hair follicle cell cycles is crucial for hair growth and alopecia research, and recommends specific techniques and future research directions.

The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.

Spiny mice are better at regenerating hair after injury than laboratory mice and could help us understand how to improve human skin repair.

ALA-photodynamic therapy helps reduce acne by causing acne cell death and lowering certain skin protein levels.

Cysteine-rich keratins evolved independently in mammals, reptiles, and birds for hard skin structures like hair, claws, and feathers.

Endo-HSE helps grow hair-like structures from human skin cells in the lab.

Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.

ALA-PDT is effective and safe for chronic X-ray dermatitis, providing complete or partial remission.

New treatments for immune disorders caused by FOXN1 deficiency are promising.

Human hair follicle dermal cells can effectively replace other cells in engineered skin.

Applying calreticulin can speed up wound healing in diabetics.

Thyroid hormones are important for skin health and changes in them can affect conditions like hair loss and eczema.

Mice without certain skin proteins had abnormal skin and hair development.

The document concludes that inherited epidermolysis bullosa is a challenging genetic condition requiring multidisciplinary care and new treatments.

The study concluded that PKP1 is essential for skin integrity and hair growth, and its dysfunction causes the symptoms of ectodermal dysplasia/skin fragility syndrome.

TPA promotes hair growth by increasing stem cell activity and activating specific cell signals.

15-lipoxygenase helps keep skin healthy by reducing inflammation.

ΔNp63α stops TAp73β from working in skin cancer by blocking its access to specific genes, not by directly interacting with it.

Meis1 is crucial for skin health and tumor development.

Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.

Different markers are found in stem cells of the scalp's hair follicle bulge and the surrounding skin.

Activin activation in skin cells speeds up wound healing without affecting scar quality.

TAF4 is important for skin cell growth and helps prevent skin cancer in mice.

Early recognition and management of skin side effects from new cancer therapies can prevent treatment delays.

A gene deletion causes the "hairless" trait in Iffa Credo rats.

COVID-19 can cause skin issues like chilblains and rashes, which may help in early detection, especially in patients without other symptoms.