September 2022 in “Research Square (Research Square)” This study found that overexpressing Rps14 in supporting cells promoted hair cell regeneration in the organ of Corti by facilitating cell proliferation and differentiation.
53 citations
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January 2012 in “Developmental Biology” EGFR signaling is essential for ear cell regeneration in both birds and mammals.
January 2024 in “Archives of Biological Sciences (Beograd)” This study found that AP collagen peptides can promote hair growth by supporting the health of hair follicle cells, as they stimulate cell proliferation, counteract apoptosis, and enhance antioxidant enzyme expression, suggesting potential as a treatment for hair loss.
30 citations
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April 2017 in “European Journal of Cell Biology” This study observed that CIP/KIP proteins play a significant role in regulating cell cycle arrest and differentiation in human hair follicles, supporting hair growth and formation in the anagen phase.
2 citations
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November 2025 in “Cells” This review presents evidence supporting the potential of adipose-derived stem cell secretome as a promising cell-free therapy for skin repair, emphasizing its application in wound healing, alopecia, skin rejuvenation, and inflammatory skin diseases.
November 2025 in “Journal of Investigative Dermatology” CBD can help hair grow by supporting scalp health and reducing inflammation.
11 citations
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January 2025 in “Regenerative Therapy” This review highlights the potential of bioengineered dermal scaffolds in tissue engineering to enhance wound healing by mimicking the dermal structure and supporting cellular processes, while also discussing recent advancements and challenges in scaffold technology.
January 1995 in “Equilibrium Research” This study suggests that supporting cells are the origin of regenerated hair cells in the avian basilar papilla, with epidermal growth factor as a potential trigger, and indicates a possibility of hair cell regeneration in mammalian vestibular epithelia.
July 2026 in “Plastic & Reconstructive Surgery Global Open” This study found that intradermal injections of plant-derived exosomes in adults with early-stage alopecia increased stem cell activity, activated Wnt signaling pathways, and reduced certain immune cell populations, providing insights into their role in hair follicle regeneration and suggesting potential for hair restoration therapy.
This study demonstrated that cryogelation of human hair keratin allows the development of 3D scaffolds with tunable properties, supporting cell adhesion and proliferation for potential biomedical applications.
December 2025 in “The Journal of Cell Biology” This study found that keratin 15 lacks the ability to sequester YAP1 in keratinocytes effectively, unlike keratin 14, and suggests that a higher K15:K14 ratio may promote a progenitor state and inhibit differentiation in epidermal keratinocytes.
November 2025 in “EXPERIMENTAL ANIMALS” In this murine study, researchers found that topical treatment with Philippine stingless bee propolis increased folliculogenesis, epidermal thickness, and melanogenesis, but not hair length, potentially supporting hair follicle regeneration and melanocyte function in chemotherapy-induced alopecia models.
133 citations
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March 1999 in “Journal of Cutaneous Pathology” This study found that keratin 15 expression in trichoepitheliomas and some basal cell carcinomas suggests a link to hair follicle stem cells in the bulge.
3 citations
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May 2017 in “British journal of dermatology/British journal of dermatology, Supplement” Certain cells around hair follicles help improve skin regeneration for potential use in skin grafts.
38 citations
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June 2016 in “Nanomedicine: Nanotechnology, Biology and Medicine” In this study, the RADA-PRG hydrogel enhanced SKP proliferation, survival, and gene expression, effectively supporting hair follicle regeneration in mice.
April 2024 in “Biomolecules” This review summarizes recent findings on the role of mesenchymal stem cell-derived exosomal microRNAs in skin regeneration and rejuvenation, discussing their potential for treating skin damage and aging, and exploring bioengineering methods to enhance therapeutic effects.
55 citations
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January 2020 in “Advances in experimental medicine and biology” This study suggests that vitamin D and its receptor may protect against the development of epidermal tumors following UV radiation by regulating specific cellular signaling pathways.
2 citations
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March 2020 in “Developmental cell” This study reported that stress can induce hair graying in mice through noradrenaline-mediated depletion of melanocyte stem cells in hair follicles, providing a mechanism that connects stress to hair color changes.
This study found that UV radiation-induced fibroblast depletion in the skin is primarily due to a deregulated inflammatory response, with T cells aiding fibroblast survival under stress.
April 2017 in “Journal of Investigative Dermatology” This study found that SM04755, a novel topical drug, inhibited inflammation, keratinocyte proliferation, and fibrosis in vitro and improved skin health in a mouse model of psoriasis, indicating potential as a topical psoriasis treatment.
This study found that elastin-like recombinamer (ELR) wound dressings promote tissue regeneration and stability without rejection in ex vivo and in vivo models, indicating potential for hard-to-heal wound treatment.
This study investigated the molecular mechanisms behind cashmere goat coat types by analyzing gene expression during hair follicle development stages, identifying regulatory pathways involved in metabolism, immune response, and the quiescent state of follicles, potentially aiding in genetic selection for improved cashmere production.
7 citations
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March 2020 in “PloS one” This study demonstrates that α-parvin is crucial for epidermal morphogenesis and hair follicle development by mediating integrin-dependent adhesion and actin organization in keratinocytes.
1 citations
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July 2022 in “Clinical, Cosmetic and Investigational Dermatology” This study suggests that the anti-inflammation and anti-oxidation properties of Taohong Siwu decoction may be linked to its effects on androgenic alopecia through specific biological processes and pathways.
November 2023 in “Hair transplant forum international” Results are not reported in this abstract, which raises the question of whether caffeine has a stimulating effect on hair growth both in laboratory settings and live subjects.
1 citations
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January 2023 in “Przegla̧d dermatologiczny” This review discusses the role of zinc in skin physiology related to vitiligo and reports no new clinical results; the authors emphasize its potential in pathogenesis and treatment.
8 citations
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November 2023 in “Frontiers in Bioengineering and Biotechnology” This article reviews recent developments in microneedles combining metallic elements and herbal compounds for wound healing, highlighting their benefits such as enhanced therapeutic efficacy and reduced toxicity, and offering a reference for future advancements in this technology.
May 2024 in “Journal of cosmetic dermatology” This study found that while caffeine and adenosine can inhibit hair loss and stimulate hair growth, more research is needed to fully understand the efficacy of shampoo formulations containing specific proportions of these compounds for hair loss treatment and prevention.
9 citations
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March 2018 in “Journal of the Formosan Medical Association” In this study, chitosan membranes enhanced melanocyte proliferation and survival by supporting both cell-cell and cell-substrate interactions, unlike polyvinyl alcohol membranes which only facilitated cell-cell interactions.
155 citations
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March 2009 in “Seminars in Cutaneous Medicine and Surgery” This review covers various strategies to manage chemotherapy-induced alopecia, highlighting that agents like AS101 and minoxidil can reduce its severity but not prevent it, with no new clinical results reported.