Search

for
Search:

Did you mean Superoxide Dismutase?

Glossary Superoxide Dismutase

enzyme that neutralizes harmful superoxide radicals in cells

Superoxide Dismutase (SOD) is an enzyme that plays a crucial role in protecting cells from damage caused by superoxide radicals, which are harmful byproducts of cellular metabolism. By converting these superoxide radicals into less harmful molecules like hydrogen peroxide and oxygen, SOD helps to mitigate oxidative stress, which is linked to various diseases and aging processes.

Related Terms

Sort by

Research

30 / 1000+ results

Efficient Intradermal Delivery of Superoxide Dismutase Using a Combination of Liposomes and Iontophoresis for Protection Against UV-Induced Skin Damage

research Efficient Intradermal Delivery of Superoxide Dismutase Using a Combination of Liposomes and Iontophoresis for Protection against UV-Induced Skin Damage

21 citations , January 2012 in “Biological and Pharmaceutical Bulletin”

This study found that using a combination of iontophoresis and liposomal delivery facilitated the effective intradermal administration of superoxide dismutase in rats, reducing oxidative skin damage from UV exposure.

Preferential Recognition of Hydroxyl Radical-Modified Superoxide Dismutase by Circulating Autoantibodies in Patients with Alopecia Areata

research Preferential Recognition of Hydroxyl Radical-Modified Superoxide Dismutase by Circulating Autoantibodies in Patients with Alopecia Areata

12 citations , January 2014 in “Annals of Dermatology”

This study found an association between hydroxyl radical-modified SOD and alopecia areata, suggesting these modifications may lead to antibody induction in the condition.

Multifaceted Roles of Superoxide Dismutases (SODs) in Cellular Homeostasis and Cancer Progression: Redox Regulation and Therapeutic Implications

research Multifaceted roles of superoxide dismutases (SODs) in cellular homeostasis and cancer progression: Redox regulation and therapeutic implications

January 2025 in “Journal of Medical Biochemistry”

This review explores the roles of superoxide dismutases in cellular processes and cancer, highlighting the potential of SOD mimetics in enhancing cancer treatment strategies, but it reports no new clinical findings.

research Protective Effect of Superoxide Dismutase Against Hair Graying in a Mouse Model¶

33 citations , January 2004 in “Photochemistry and Photobiology”

This study found that applying superoxide dismutase (SOD) gel on mice protected against hair graying caused by UV-A and psoralen exposure, suggesting photosensitization may be a factor in hair aging.

research Protective Effect of Superoxide Dismutase Against Hair Graying in a Mouse Model^¶

12 citations , November 2004 in “Photochemistry and Photobiology”

In this study, a superoxide dismutase gel prevented hair graying in mice exposed to photosensitization, suggesting that antioxidants can protect against oxidative damage involved in hair aging.

research Machine Learning Guided Discovery of Superoxide Dismutase Nanozymes for Androgenetic Alopecia

3 citations , October 2022 in “Nano Letters”

This study found that a microneedle patch using manganese thiophosphite showed greater hair regrowth potential compared to minoxidil, even with less frequent application, for treating androgenetic alopecia.

research SUPEROXIDE DISMUTASE LOADED NIOSOMES DELIVERY TO HAIR FOLLICLES: PERMEATION THROUGH SYNTHETIC MEMBRANE AND GUINEA PIG SKIN

2 citations , August 2019 in “International Journal of Applied Pharmaceutics”

This study explored the use of SOD-loaded niosomes as carriers to enhance the delivery of superoxide dismutase into hair follicles on guinea pig skin, finding that niosomes improved SOD penetration and preservation compared to free SOD, suggesting their potential as effective delivery vehicles.

Evaluation of Antioxidant and Oxidant Status, Including Levels of Malondialdehyde and Superoxide Dismutase, in the Indian Population with Alopecia Areata

research Evaluation of antioxidant and oxidant status, including levels of Malondialdehyde (MDA) and Superoxide Dismutase (SOD), in the Indian population with alopecia areata

August 2022 in “International Journal of Health Sciences (IJHS) (En línea)”

This study observed that patients with alopecia areata had significantly different levels of oxidative stress markers SOD and MDA compared to controls.

research Differences of Superoxide Dismutase (SOD) Enzyme Levels Based on the Severity of Androgenetic Alopecia in Men

January 2020 in “International journal of scientific and research publications”

This article discusses androgenetic alopecia's mechanisms but reports no new study results.

research Assessment of Zinc and Copper Contents in Scalp Hair and Serum and Superoxide Dismutase, Glutathione Peroxidase and Malondialdehyde in Serum of Androgenetic Alopecia and Alopecia Areata Patients

4 citations , October 2011 in “Medical journal of Tabriz University of Medical Sciences and Health Services”

This study suggests that lower levels of zinc and copper in hair and serum, along with altered oxidative stress markers, may contribute to the development of alopecia areata and androgenetic alopecia.

research Topical application of synthetic melanin promotes tissue repair

19 citations , November 2023 in “npj Regenerative Medicine”

This study found that synthetic melanin particles applied topically in mouse injury models improved wound healing, showing potential as a therapy for accelerated healing, including in human skin explants.

research Improvement of Antioxidant Defences in Keratinocytes Grown in Physioxia: Comparison of 2D and 3D Models

9 citations , June 2023 in “Oxidative Medicine and Cellular Longevity”

This study reports that keratinocytes grown under low oxygen conditions (physioxia) demonstrated reduced reactive oxygen species production and increased antioxidant enzyme activity compared to those in higher oxygen conditions, highlighting the role of oxygen in regulating skin antioxidant defenses.

research Antioxidants in dermatology

86 citations , June 2017 in “Anais Brasileiros de Dermatologia”

This review discusses the role of antioxidants in managing oxidative skin damage and reports no new results, emphasizing the need for understanding their mechanisms, limitations, and risks for safe use.

research Role of Oxidative Stress in Polycystic Ovary Syndrome

65 citations , May 2010 in “Current Women's Health Reviews”

This review discusses oxidative stress's role in polycystic ovary syndrome and examines various biomarkers to understand its impact on the disorder's pathogenesis, but reports no new clinical results.

Melatonin Promotes Secondary Hair Follicle Development in Early Postnatal Cashmere Goats and Improves Cashmere Quantity and Quality by Enhancing Antioxidant Capacity and Suppressing Apoptosis

research Melatonin promotes secondary hair follicle development of early postnatal cashmere goat and improves cashmere quantity and quality by enhancing antioxidant capacity and suppressing apoptosis

46 citations , March 2019 in “Journal of Pineal Research”

The study found that melatonin treatment in early postnatal cashmere goats increased both the quantity and quality of cashmere by promoting secondary hair follicle development and enhancing antioxidant enzyme activities.

research Is Xanthine oxidase activity in polycystic ovary syndrome associated with inflammatory and cardiovascular risk factors?

26 citations , June 2016 in “Journal of Reproductive Immunology”

This study found that in women with polycystic ovary syndrome, xanthine oxidase activity is a useful marker for oxidative stress and is positively correlated with inflammatory markers and cardiovascular disease risk factors.

research Patients with vitiligo present fewer cardiovascular risk factors: results from a case–control study

17 citations , December 2011 in “Journal of the European Academy of Dermatology and Venereology”

People with vitiligo may have a lower risk of heart disease.

research Biochemical and Histopathological Evaluation of the Radioprotective Effects of Melatonin Against Gamma Ray-Induced Skin Damage

15 citations , November 2018 in “Current radiopharmaceuticals”

This study found that melatonin, when administered to Wistar rats prior to and after radiation exposure, reduced oxidative stress markers and histopathological damage in skin tissue compared to radiation alone, suggesting it may effectively prevent and treat radiation-induced skin injury.

research In Vitro and In Vivo Anti-Aging Effect of Coffee Berry Nanoliposomes

13 citations , September 2023 in “Molecules”

This study found that encapsulating coffee berry extract in nanoliposomes improved its stability, reduced toxicity, and enhanced its anti-aging effects on skin elasticity and lightening more than free extract.

research Oxidative stress in androgenetic alopecia.

13 citations , March 2017 in “PubMed”

In this study, patients with androgenetic alopecia showed significantly decreased antioxidant activity and increased oxidative stress markers, suggesting a role for oxidative stress in the condition.

research Alterations in transcriptome and antioxidant activity of naturally aged mice exposed to selenium-rich rice

10 citations , April 2019 in “Environmental Science and Pollution Research”

In this study, selenium-rich diets enhanced antioxidant activity in aged mice, suggesting potential biological benefits, although further trials are needed to fully understand long-term risks and benefits.

research Transplanted hair follicle mesenchymal stem cells alleviated small intestinal ischemia–reperfusion injury via intrinsic and paracrine mechanisms in a rat model

6 citations , October 2022 in “Frontiers in Cell and Developmental Biology”

This study suggests that hair follicle mesenchymal stem cells may alleviate small intestinal ischemia-reperfusion injury in rats by promoting angiogenesis, reducing apoptosis, and enhancing intestinal stem cell expression.

research Lactobacillus paracasei HY7015 and Lycopus lucidus Turcz. Extract Promotes Human Dermal Papilla Cell Cytoprotective Effect and Hair Regrowth Rate in C57BL/6 Mice

3 citations , November 2022 in “Molecules/Molecules online/Molecules annual”

This study found that ingesting Lactobacillus paracasei HY7015 and Lycopus lucidus Turcz. extract promoted hair regrowth and follicle maturation in mice by enhancing cytoprotective effects and growth factor expression.

research Single dose gamma irradiation induced angiogenesis in rat skin hair follicles

3 citations , October 2020 in “Internatuinal Journal of Radiation Research”

This study reports that γ-ray exposure in rats led to dermal endothelial proliferation, new vessel formation around hair follicles, and increased inflammatory markers, suggesting possible early stimulatory effects on hair growth.

research Exploring the potential effect and mechanisms of protocatechuic acid on human hair follicle melanocytes

3 citations , May 2020 in “Acta pharmaceutica”

The researchers reported that protocatechuic acid reduced melanin synthesis and enhanced antioxidant activity in cultured human hair follicle melanocytes, indicating potential for skin whitening applications.

research Oxidative Stress in Alopecia Areata and its Association with Disease Severity, Treatment and Autoimmunity

3 citations , January 2015 in “Turkiye Klinikleri Journal of Medical Sciences”

The researchers reported that corticosteroid treatments for alopecia areata led to clinical improvement but did not significantly alter oxidative stress markers, suggesting a limited regulatory effect on these systems.

research [Effects of the extract from bergamot and boxthorn on the delay of skin aging and hair growth in mice].

3 citations , August 2003 in “PubMed”

This study found that bergamot and boxthorn extract significantly improved skin antioxidant activity and collagen content while promoting hair growth in mice.

research Effects of supplementation with two probiotic strains (Lactobacillus helveticus and Bifidobacterium longum) on hormonal status, oxidative stress, and clinical symptoms in women with polycystic ovary syndrome: a randomized clinical trial

2 citations , November 2025 in “Nutrition Journal”

This study found that an 8-week supplementation with specific probiotic strains improved hormonal markers and oxidative stress while decreasing inflammation in women with PCOS, although clinical symptoms like acne and hirsutism showed no significant improvement compared to the placebo group.

research Evaluation of Resistance Resources and Analysis of Resistance Mechanisms of Maize to Stalk Rot Caused by Fusarium graminearum

2 citations , July 2023 in “Plant Disease”

In this study, researchers examined 120 inbred maize lines infected with Fusarium graminearum, discovering that some demonstrated significant resistance to stalk rot, correlated with specific gene pathways. This highlights potential genes and pathways for enhancing disease resistance in maize.

research Zinc‐Coordinated Trienzyme Nanogel Cascade Therapy for Accelerated Post‐Pancreatectomy Cutaneous Wound Healing

1 citations , July 2025 in “Advanced Materials”

This study reports on a zinc-coordinated tri-enzyme nanogel system (Zn@nGSC) that mimics natural enzymatic processes to enhance enzymatic activity and cascade efficiency, showing potential in wound healing, hyperglycemia treatment, and antibacterial effects in a murine model of post-pancreatectomy.