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Gemcitabine and paclitaxel are effective and safe as first-line treatment for metastatic breast cancer.

The meeting discussed medical findings, including benefits of certain treatments for cancer and heart conditions, and highlighted issues like poor adherence to preventive measures and skill gaps among interns.

Keratinocytes and adipose-derived stem cells can effectively heal difficult skin wounds.

Glycerin in hand cream can cause allergic skin reactions.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

A cat with skin bumps and itching had high blood fats and skin infections, which improved with diet and medication changes.

Eating high-glycemic and dairy foods can increase hormones that may cause acne and other health issues.

The document concludes that non-scarring alopecias can be reversed, but scarring alopecias cause permanent hair loss.

Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.

Long-term use of azole antifungals can cause hair loss, hormonal imbalances, and severe skin reactions.

Spironolactone is effective and safe for treating hair loss, excessive hair growth, and acne.

Niosomes are promising for skin drug delivery, offering benefits like improved drug penetration and stability.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Drug advertising has greatly increased, changing consumer behavior and raising concerns about its influence on healthcare and patient protection.

Activin helps skin growth and healing mainly through stromal cells and affects keratinocytes based on its amount.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Hair problems can be caused by genetics or the environment, and treatment should focus on the cause and reducing hair damage.

Zinc can help with some skin problems, but its effectiveness varies depending on the condition.

Iontophoresis improves minoxidil delivery for alopecia treatment.

Spironolactone is effective for acne, hidradenitis suppurativa, female hair loss, and hirsutism but is underused in dermatology.

The document concludes that parathyroid diseases have a range of clinical features and outcomes, with some conditions being treatable and others having a high risk of mortality.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

New genes and pathways are important for testosterone production and male sexual development.

Researchers found 15 new genetic links to skin traits in Japanese women.

Recognizing oral symptoms can help diagnose and treat blood and nutritional diseases early.

Quercetin may help with PCOS symptoms, but more research is needed.

Gilles de la Tourette syndrome is treatable, with behavioral therapy as a recommended first option and other treatments available for more severe cases.

The guide explains how to study human skin fat cells and their tissue, aiming to improve research and medical treatments.