January 2019 in “ARC journal of pharmaceutical sciences” This review traces the historical understanding and treatment of acne across ancient Egyptian, Greek, and Roman civilizations, but provides no new clinical findings.
January 2025 in “International Journal for Research Trends and Innovation” This review examines the factors contributing to Polycystic Ovary Syndrome in India, discussing genetic, lifestyle, and environmental influences, but provides no new clinical results.
75 citations
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November 2016 in “Medicines” This review discusses the properties and therapeutic potentials of beta-sitosterol, highlighting a need for more detailed studies on its mechanisms and long-term effects in humans; it reports no new results.
5 citations
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January 2013 in “Journal der Deutschen Dermatologischen Gesellschaft” The document concludes that individualized treatment for malignant epithelial tumors is necessary and more research on metastatic squamous cell carcinoma treatments is needed.
4 citations
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January 2022 in “Current pharmaceutical design” This review discusses the benefits and applications of microsponges delivery systems in drug delivery, particularly for topical treatments, and reports no new clinical findings.
June 2014 in “British Journal of Dermatology” Eczema patients have a lower skin lipid to protein ratio, older and longer-staying hospital patients are more likely to get pressure ulcers, hair loss in AGA is linked to muscle degeneration, vitamin D deficiency is common in alopecia areata and linked to its severity, standard liver tests don't effectively detect fibrosis in psoriasis patients on methotrexate, and bullous pemphigoid patients have a higher death risk but combination therapy may reduce it.
2 citations
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August 1987 in “Australasian Journal of Dermatology” This review discusses skin diseases related to contraceptive use, reporting potential issues with oral contraceptives and infrequent reactions to mechanical or barrier methods without new clinical findings.
1 citations
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July 2018 in “Elsevier eBooks” This review discusses the pathogenesis and clinical features of androgenetic alopecia, highlighting potential links to fibrosing alopecia and suggesting the need for combined therapeutic approaches; it reports no new clinical results.
January 2017 in “Springer eBooks” This article reviews the classification, pathogenesis, and treatment options for cutaneous lupus erythematosus and reports no new clinical findings.
8 citations
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February 2025 in “Pharmaceuticals” This source reviews the potential of polyphenols as therapeutic and preventive treatments for common skin disorders such as acne, fungal infections, dermatitis, alopecia, and skin cancer, emphasizing their anti-inflammatory and antimicrobial effects and ability to penetrate the skin barrier.
August 2025 in “Journal of Cosmetic Dermatology” In this systematic review, researchers examined various treatments for axillary hyperpigmentation, finding that Q-switched Nd:YAG laser and intense pulsed light showed significant improvement with minimal adverse effects; desonide and Cyperus rotundus oil were also notably effective among topical treatments.
December 2024 in “Health Science Reports” This review found that topical metformin shows potential as a treatment in dentistry for periodontitis and in dermatology for conditions like wound healing and acne, but results for melasma are inconsistent.
2 citations
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December 2025 in “Gels” This study developed a biomimetic 3D skin model with vascularization potential to assess the impact of nano-zinc oxide (nano-ZnO), finding that nano-ZnO significantly influenced genes related to apoptosis, inflammation, and oxidative stress in skin cells.
32 citations
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January 2022 in “International Journal of Molecular Sciences” This review discusses the impact of melatonin and its metabolites on skin aging, summarizing how they may serve as "aging neutralizers" through their anti-oxidative and anti-inflammatory properties, but reports no new clinical results.
33 citations
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July 2021 in “Clinical, Cosmetic and Investigational Dermatology” This review discusses the use of nanocarrier technology in functional cosmetics to enhance skin penetration, increase ingredient stability, and allow codelivery of active ingredients, without reporting new clinical results.
41 citations
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September 2021 in “Materials” This review discusses the role of biomaterials and colloidal drug delivery systems in promoting tissue regeneration within regenerative medicine, but it reports no new clinical results.
26 citations
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December 2022 in “Molecules” This review discusses various nanotechnology-based strategies for managing melasma and reports no new clinical results, highlighting the potential of innovative drug delivery systems in treating hyperpigmentation.
10 citations
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August 2024 in “ACS Omega” This review discusses the use of nanomaterials in cosmetics, highlighting their benefits like enhanced stability and skin penetration, while also noting potential health risks and the role of natural ingredients in formulations.
9 citations
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January 2014 in “World journal of clinical cases” This review discusses the clinical and pathologic features of follicular contact dermatitis, highlighting neomycin as a potential cause, and reports no new clinical results.
4 citations
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September 2025 in “International Journal of Molecular Sciences” This review discusses the dermatological applications and potential health benefits of Epigallocatechin-gallate (EGCG) from green tea, but provides no new clinical findings.
1 citations
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October 2025 in “Beni-Suef University Journal of Basic and Applied Sciences” This study reviews lipid-based nanocosmeceuticals and reports that they enhance therapeutic effectiveness in dermatological applications by improving skin hydration, reducing wrinkles, and effectively managing conditions like psoriasis and eczema, though further large-scale trials and regulatory alignment are needed for clinical use.
September 2025 in “Journal of International Medical Research” In this case study, researchers documented chronic dermatitis and ulcerative lesions in a 70-year-old Syrian man following chlorine gas exposure during the conflict, highlighting the need for healthcare planning and registries to manage long-term effects in affected populations.
November 2024 in “International Medical Case Reports Journal” Glucocorticoid treatment in lupus can cause oral lesions, which need early diagnosis and comprehensive care.
January 2024 in “Journal of tissue engineering” In this study, researchers used a human skin organoid model to show that solar UV exposure damages hair follicles and skin, while exosomes from mesenchymal stem cells reduced inflammation and supported hair follicle regeneration.
January 2023 in “Dermatologic Therapy” This study evaluated a novel hand-held low-level light therapy device for treating mild-to-moderate acne, finding it significantly reduced inflammatory lesions and moderate acne severity without severe adverse reactions, while also reducing Cutibacterium acnes viability in vitro.
September 2024 in “Journal of Cosmetic Dermatology” Follow these guidelines to safely and effectively use energy-based devices in aesthetic treatments.
13 citations
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September 2023 in “Molecules” This study found that encapsulating coffee berry extract in nanoliposomes improved its stability, reduced toxicity, and enhanced its anti-aging effects on skin elasticity and lightening more than free extract.
12 citations
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May 2022 in “Plants” This review highlights the potential of nano-phytopharmaceuticals in improving the bioavailability and efficacy of phytochemicals for treating locomotor, dermal, reproductive, and urinary tract disorders, but notes that more clinical and preclinical research is needed to establish their safety and efficacy for human use.
9 citations
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January 2021 in “Mediators of Inflammation” In this study, 15d-PGJ2 administered in a topical cream inhibited oxidative and inflammatory skin changes caused by UVB radiation in hairless mice, suggesting it as a promising treatment approach.
This study observed that methylene blue, a mitochondrial-targeted antioxidant, promotes hair follicle stem cell proliferation and viability through reduced oxidative stress and enhanced β-catenin signaling, and it may also protect against hair loss related to glucagon-like peptide-1 receptor agonists by reducing metabolic stress.