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This study found that intrinsic reactive oxygen species drive the hair follicle cycle progression through DNA damage and repair, apoptosis, and macrophage polarization, influencing hair loss and regeneration dynamics in mice.

This study found that PBX1 overexpression reduces hair follicle-derived mesenchymal stem cell senescence and apoptosis by alleviating ROS-mediated DNA damage, rather than enhancing DNA repair.

This study found that administering calcium blockers verapamil or nimodipine significantly preserved auditory function and hair cell survival in Cx26-cKO mice, suggesting potential protective effects for other inner ear disorders.

This study found that selected polymeric pretreatments on hair can significantly reduce breakage and protect against thermal damage from hot flat irons by maintaining cuticle integrity and moisture.

In this 24-week study, oral supplementation with hydrolyzed low-molecular-weight porcine placental peptides significantly improved scalp elasticity, hair diameter, tensile strength, surface roughness, and luster compared to placebo, suggesting its potential as a nutritional intervention for age-related scalp and hair changes.

This study found that near-infrared LED therapy enhanced ATP synthesis, reduced reactive oxygen species, and promoted collagen production and hair growth more effectively than white LEDs in human skin cells and a photoaging mouse model.

This study found that PBX1 overexpression reduces hair follicle-derived mesenchymal stem cell senescence and apoptosis by interacting with SIRT1 and PARP1, highlighting a potential mechanism for addressing aging-related diseases.

This study investigated the effects of the 60% alcohol extract from Alnus sibirica and its active compound, oregonin, on hair health, observing anti-oxidative and anti-apoptotic benefits in human hair dermal papilla cells exposed to oxidative stress, suggesting potential as natural materials for hair loss prevention.

In this study, the researchers identified a PBX1-SIRT1-PARP1 axis that plays a crucial role in reducing senescence and apoptosis in hair follicle-derived mesenchymal stem cells.

This study reports that human adipose-derived stem cells cultured with platelet lysate instead of fetal bovine serum demonstrate enhanced stress resistance, reduced cellular aging, and faster wound healing in mice, due in part to upregulated stress response and proliferation genes.

This study found that Origanum vulgare extract significantly ameliorated finasteride-induced liver and kidney damage in mice by improving biochemical indices, reducing inflammation, and enhancing antioxidant status in a dose-dependent manner.

This study highlights the potential of stem cell-derived extracellular vesicles to treat UV-induced skin damage by modulating key signaling pathways, though challenges like EV composition variability and skin barrier penetration remain, underscoring the need for further research into optimized delivery methods for effective therapies.

This case report describes a 7-year-old girl who developed radiation-induced alopecia after a neurointerventional procedure, with dermoscopy revealing specific hair and scalp patterns that helped diagnose this rare complication. The findings highlight the importance of dermoscopy in distinguishing RIA from other alopecic disorders in children.

This case report describes how a 23-year-old woman experienced eyebrow thinning and hair loss linked to cosmetic use, with diagnostic tests confirming follicular damage. Discontinuing the product led to eyebrow regrowth, highlighting potential risks from cosmetics and the value of non-invasive diagnostics for evaluation.

This study found that a supplement containing medicinal plant extracts, amino acids, and vitamins decreased hair loss and increased hair thickness over three months, without significant side effects, in participants with hair loss concerns.

This study found that topically applied nano-Zinc oxide accumulated in hair follicles and induced apoptosis in hair follicle stem cells, indicating a potential risk to skin homeostasis.

This study reports that topical finasteride significantly reduced scalp and plasma dihydrotestosterone in men and women without altering serum testosterone levels, with promising preliminary results.

This study found that sulforaphane-rich broccoli sprout extracts reduced UV-induced erythema by 37.7% in humans, suggesting a protective strategy against UVR damage.

This study proposes a simple fluorescence method to evaluate hair damage and protection, suggesting that emissive properties of hair can aid in substantiating cosmetic claims.

This chapter reviews the anatomy and structure of hair, discusses hair damage and analyses, and explores methods for processing hair changes, but presents no new research findings.

This study found that PM2.5 exposure induced oxidative stress in human keratinocytes and mouse skin, causing cellular damage, which was mitigated by the antioxidant N-acetyl cysteine.

In this study, researchers found that Asian hair contains more integral lipids than European or African hair, which may protect it better from UV-induced damage.

This study found that the small molecule honokiol may protect against inflammation, collagen breakdown, and cell damage caused by cigarette smoke in skin cells cultured in vitro.

This study found that thermal hair-straightening devices significantly damaged the cuticle and cortex of virgin Asian and Caucasian hair, with Asian hair experiencing more protein loss than Caucasian hair.

This study found that DNA damage in obese women was linked to serum 25-hydroxyvitamin D and hair chromium levels, with higher serum vitamin D associated with less damage and higher chromium with more damage.

In this study, zinc oxide nanoparticles were synthesized using a sustainable method from the Lepidium sativum L. plant, and incorporating these nanoparticles into Sunblock Lotion significantly increased its sun protection factor.

This review explores how radiation-induced hair graying can be used as a model to study the mechanisms behind hair graying, focusing on cellular senescence and potential therapeutic targets to address age-related changes. Results are not provided.

The study found that safflower extract may help protect human follicle dermal papilla cells from cisplatin-induced damage, suggesting its potential as an adjuvant in chemotherapy to mitigate hair follicle cell damage.

Finasteride use for hair loss is linked to an increased risk of suicidal thoughts and a higher risk of suicide.

Finasteride, a hair loss drug, is linked to increased suicidal thoughts, particularly when used for hair loss.