7 citations
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June 2020 in “Journal of The European Academy of Dermatology and Venereology” This article discusses the role of Minoxidil Sulfotransferase Enzyme (SULT1A1) genetic variants in predicting the response to oral minoxidil for treating female pattern hair loss, without presenting new research findings.
1 citations
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June 2021 in “Journal of Cosmetic Dermatology” In this study, the addition of a SULT1A1 enzyme booster to daily 5% minoxidil treatment significantly increased hair regrowth in men with androgenic alopecia compared to minoxidil alone.
October 2024 in “International Journal of Research in Medical Sciences” This study found that adding a SULT1A1 enzyme booster to minoxidil treatment improved hair growth response in 65% of androgenetic alopecia patients who were previous non-responders to minoxidil alone, with females benefiting more than males.
This study reported the genotypic and allelic frequencies of seven SNPs associated with androgenetic alopecia in Mexican individuals, highlighting significant differences in one SNP between cases and controls in Western Mexico.
November 2020 in “Postepy Dermatologii I Alergologii” This review discusses the potential of using SULT1A1 expression in the scalp as a biomarker to predict response to minoxidil treatment for androgenetic alopecia, but reports no new clinical results.
July 2025 in “Jurnal Farmasi Sains dan Praktis” This study found that breast cancer patients treated with the docetaxel-doxorubicin regimen experienced various adverse drug reactions, with nausea being the most common and mainly mild in severity.
27 citations
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November 2013 in “Dermatologic Therapy” This study suggests that a hair follicle enzyme assay may predict response to minoxidil treatment for androgenetic alopecia with high sensitivity and specificity in a preliminary analysis.
18 citations
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January 2020 in “Acta dermato-venereologica” This overview discusses advancements in the understanding of molecular genetics in heritable keratinization disorders, focusing on recent cases of inherited ichthyosis, and reports no new clinical results.
1 citations
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July 2024 in “Journal of Cosmetic Dermatology” This study found that 63.4% of androgenetic alopecia patients showed clinical improvement after 6 months of low-dose oral minoxidil, with patients having low sulfotransferase activity in hair follicles responding more favorably than those with high enzyme activity.
December 2023 in “Journal of Trace Elements in Medicine and Biology” This study found that nano-sized molybdenum accelerated hair growth and enhanced the effectiveness of minoxidil in a mouse model by reducing oxidative stress-related molecules.
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, the reconstructed skin epidermal model derived from hair follicles showed gene expression and enzyme functionality consistent with native human skin, suggesting its viability for studying skin metabolism and potential toxicity of dermo-cosmetic ingredients.
March 2026 in “Mini-Reviews in Medicinal Chemistry” This review reports that pharmacogenomic variations in the SULT1A1 enzyme significantly influence the response to minoxidil treatment for alopecia, suggesting personalized therapeutic strategies could improve efficacy while emerging pharmaceutical technologies aim to optimize oral minoxidil's absorption and minimize side effects.
September 2025 in “Cosmetics” This study found that using a pharmacogenetic panel with 26 SNPs can improve treatment outcomes for androgenetic alopecia, as overall response rates to minoxidil, finasteride, and dutasteride were high, and specific genetic markers predicted poor responses to these drugs.
August 2025 in “International Journal of Molecular Sciences” This meta-analysis found that among topical OTC treatments for male androgenetic alopecia, minoxidil 5% applied twice daily was the most effective in increasing total hair density over 24 weeks.
April 2024 in “Journal of cosmetic dermatology” This study found that SULT1A1 enzyme activity, crucial for activating minoxidil, is significantly lower in eyebrow and eyelash follicles compared to scalp follicles, suggesting that additional sulfotransferase supplementation might enhance minoxidil-based hair growth treatments for these areas.
October 2023 in “International Journal of Pharmaceutics” This study found that ethosome-loaded minoxidil and tocopherol acetate improved hair regeneration and regulated the microenvironment around hair follicles better than commercial minoxidil in androgenic alopecia model mice, showing promise as a treatment strategy.
September 2023 in “Medicina-lithuania” In this study, DNA analysis of patients with androgenetic alopecia and alopecia areata indicated potential differences in treatment response based on genetic makeup across Romanian and Brazilian populations, notably involving genes like GR-alpha and SULT1A1, which may guide personalized treatment strategies.
August 2023 in “Journal of Cosmetic Dermatology” This study characterized the activity of naturally occurring minoxidil sulfotransferase enzymes in various plants and found that seven out of ten botanical extracts showed significant activity, suggesting these could potentially enhance minoxidil response in treating androgenetic alopecia.
This study evaluated genetic differences in hair loss patients from Romania and Brazil, finding that specific gene variations were more common in Brazilian patients. The researchers suggest certain drugs may be more effective based on these genetic markers, but most genes showed no population differences.
March 2023 in “Медицинский совет” In this study, 77% of androgenetic alopecia patients showed hair regrowth with minoxidil treatment, while lower SULT1A1 enzyme activity, ATP concentration, and initial hair density were identified as negative prognostic factors for treatment response.
9 citations
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August 2013 in “Middle East Fertility Society Journal” This study found that the hospital-based prevalence of polycystic ovarian syndrome among Omani women of reproductive age was 2.8%, similar to rates reported in other countries.
1 citations
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February 2025 in “Frontiers in Nutrition” This study found that a postbiotic derived from hawthorn and probiotics can alleviate loperamide-induced constipation in aged mice by regulating several physiological processes, including intestinal water and sodium metabolism, maintaining gut flora and barrier, reducing inflammation, and enhancing short-chain fatty acid metabolism.
March 2026 in “Journal of Personalized Medicine” In this study involving South African breast cancer patients, researchers identified certain genetic variations in cytochrome P450 and other enzymes potentially linked to differences in tamoxifen treatment outcomes, suggesting a need for more comprehensive pharmacogenomic studies to optimize therapy in African populations.
This study found that a data-driven model using XGBoost effectively predicts individualized responses to minoxidil for androgenetic alopecia, outperforming traditional methods in accuracy and reliability.
14 citations
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July 2001 in “American Journal of Human Genetics” Haplogroup X found in Altaian population supports Amerindian origin.
December 2024 in “Indian Journal of Veterinary Public Health” This study focused on equine sarcoid, the most common tumor in horses, and described its types, clinical signs, and histopathological characteristics such as hyperkeratosis and changes in the hair follicle and dermis.
12 citations
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June 2020 in “Sultan Qaboos University medical journal” This review discusses the role of the TRPV4 channel in skin physiology and pathology, highlighting its potential as a therapeutic target for skin disorders, but reports no new clinical results.
11 citations
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May 2020 in “Sultan Qaboos University medical journal” This study found that while bariatric surgery in Bahrain effectively accelerated weight loss, it was also associated with nutritional deficiencies and gastrointestinal complications.
5 citations
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February 2016 in “Sultan Qaboos University medical journal” This case report describes a patient with a severe pruritic rash and hair loss in both axillary regions, with no fluorescence under a Wood's lamp and hair follicle-centred papules observed through dermoscopy.
5 citations
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August 2015 in “Sultan Qaboos University medical journal” This case report highlights an atypical presentation of vitamin B12 deficiency in a 28-year-old man with reversible symptoms including localized hand hyperpigmentation and megaloblastic anemia, resolved after B12 supplementation.