48 citations
,
July 1996 in “Human & Experimental Toxicology” Human enzymes can detoxify harmful substances but might also increase their cancer risk.
9 citations
,
March 1993 in “Biochemical Pharmacology” This study suggests that rat skin may synthesize minoxidil sulphate independently, implying the skin could contribute to minoxidil's hair growth promotion without help from the liver or other organs.
32 citations
,
January 1990 in “Clinical Endocrinology” This study found that women with female pattern androgenic alopecia have significantly higher levels of certain androgens and androgen sulfates compared to normal premenopausal women, suggesting markers for diagnosis and treatment efficacy.
4 citations
,
January 1989 in “Journal of Steroid Biochemistry” This study suggests that 5-ADIOL-S may contribute to the synthesis of potent androgens in peripheral tissues, and 3 alpha-DIOL-S could be a marker of androgen metabolism in various female patient groups.
86 citations
,
July 1990 in “British Journal of Pharmacology” Diazoxide, minoxidil sulphate, and cromakalim relax rat blood vessels by opening K+ channels, with some differences in their actions.
77 citations
,
January 2015 in “International Journal of Biological Macromolecules” This study developed minoxidil sulphate-loaded chitosan nanoparticles that doubled drug delivery to hair follicles in vitro compared to a control solution, suggesting potential for improved alopecia treatment.
68 citations
,
February 1996 in “Obesity Surgery” This study found that significant hair loss in about one-third of patients after vertical gastroplasty was reversed by zinc supplementation.
57 citations
,
January 2004 in “Journal of Radiation Research” This study found that zinc supplementation reduced the severity and delayed the onset of radiation-induced skin injury in rats, with the greatest protection observed at a dose of 10 mg/kg/day.
45 citations
,
August 2011 in “Journal of Microencapsulation” This study found that chitosan microparticles containing minoxidil sulphate sustained its release and may hold potential for targeted topical treatment of alopecia.
33 citations
,
May 1991 in “British Journal of Pharmacology” Cromakalim relaxes various blood vessels, while minoxidil sulphate is more selective; they likely act on different potassium channels.
30 citations
,
June 2006 in “British journal of dermatology/British journal of dermatology, Supplement” In this study, oral zinc sulphate was found to cause hair hypopigmentation and significantly inhibit eumelanogenesis in mice.
27 citations
,
April 2007 in “European Journal of Pharmacology” Progesterone increases alcohol tolerance and withdrawal anxiety, while DHEAS prevents them.
25 citations
,
July 2015 in “Colloids and Surfaces B: Biointerfaces” This study found that microencapsulation combined with iontophoresis can significantly enhance the delivery of minoxidil sulphate to hair follicles, suggesting a synergetic approach for topical drug targeting.
20 citations
,
January 2014 in “Journal of Clinical & Experimental Dermatology Research” This study found that oral zinc sulphate was effective for treating patchy alopecia areata, with a low relapse rate observed after discontinuing treatment.
4 citations
,
March 2020 in “Scientific Reports” This study reported that polymeric nanofibers containing minoxidil sulphate showed effective encapsulation and stability, with minimal concentration loss over six months, making them potentially ideal for delivering this unstable drug in a more visually appealing and easier-to-apply form.
3 citations
,
January 1985 in “British Journal of Dermatology” In this study, a low concentration zinc sulphate solution was investigated for managing recurrent herpes simplex infections, but no new clinical results were reported.
2 citations
,
August 2016 in “Química Nova” This study concluded that chitosan nanoparticles loaded with minoxidil effectively target hair follicles and reduce dermal exposure compared to iontophoresis, despite similar drug delivery potential to the follicles.
2 citations
,
June 2011 in “Journal of clinical and experimental investigations” This study found that oral zinc sulphate appeared effective and safe for treating thallium poisoning, particularly in reducing hair and skin symptoms and mitigating its severe progression in patients.
1 citations
,
July 2022 in “BMC Women s Health” This report describes a rare case of elevated serum DHEAS levels in a postmenopausal woman, linked to an ovarian sex cord-stromal tumor rather than the adrenal glands, challenging common assumptions about androgen sources.
April 2025 in “Journal of Biomedicine and Translational Research” This case report describes the successful treatment of a post-excisional biopsy dehisced wound in an 11-year-old girl using 1% framycetin sulphate tulle combined with ozonated oil as adjuvant therapy, leading to wound healing with some complications like secondary cicatricial alopecia.
April 2023 in “Clinical theriogenology” This report highlights the usefulness of specific diagnostic procedures, including penile/preputial cytology and transabdominal ultrasonography, in diagnosing cryptorchidism and Sertoli cell tumors in dogs with generalized skin conditions.
June 2011 in “Journal of clinical and experimental investigations” This study suggests that oral zinc sulphate may be an effective and safe treatment for thallium poisoning, particularly in improving dermatological symptoms and reducing the progression of the condition.
13 citations
,
August 1997 in “Steroids” Finasteride effectively lowers specific hormone levels, helping monitor treatment progress.
1 citations
,
January 2017 in “SAGE Open Medical Case Reports” This case report suggests that exacerbations of alopecia areata in a 40-year-old woman may be associated with sodium tetradecyl sulphate foam sclerotherapy treatments for varicose veins.
1 citations
,
January 2024 in “Pharmaceuticals” The researchers reported that dPGS-PCL as a carrier improved the penetration of tofacitinib in an ex-vivo human skin model compared to free tofacitinib, but did not show significant differences in inhibiting IL-6 and IL-8 during short incubation.
1 citations
,
July 2020 in “Reviews in separation sciences” This study developed a simple method to determine finasteride, indapamide, and tiemonium methylsulfate in pharmaceuticals by using their ability to form silver nanoparticles measurable via spectrophotometry.
13 citations
,
September 2019 in “Scientific Reports” In this study, high levels of the protein Flii in mice were associated with worsened symptoms and inflammation in ulcerative colitis, suggesting Flii may inhibit mucosal healing.
January 2025 in “Analytical Methods” This study reports the development of a fluorescent ionic liquid that shows high sensitivity and selectivity for detecting dextran sulfate sodium, with potential applications in clinical diagnostics and environmental monitoring.
29 citations
,
September 1990 in “Biochemical Journal” This study reports the purification of a specific sulphotransferase from rat liver that catalyzes the sulphation of minoxidil, potentially implicating it in minoxidil's bioactivation.
18 citations
,
November 1994 in “Histochemical Journal” This study explored the localization of phenolsulphotransferase in human embryonic and fetal kidneys, finding distinct patterns of PST immunoreactivity in developing mesonephric and metanephric structures over time.