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This review discusses the dermatologic care of transgender individuals and highlights the need for more quantitative research to improve clinical understanding and support future studies.

This study reports that long-term use of finasteride does not affect bone mineral density in men with benign prostatic hyperplasia over a four-year period.

This review discusses neutrophil-associated and infiltrative scarring alopecias, as well as promising new treatments, but reports no new clinical results.

This article describes the 25Up study on psychological and behavioral risk factors for mental illness in Australian twins and their siblings and reports prevalence data for various mental disorders.

This study found that ovariectomized and finasteride-treated rats showed significant tear film deficiency and downregulation of sex steroid receptors in ocular tissues, suggesting potential models for studying dry eye disorders.

In this study, XMU-MP-1 unexpectedly reduced cell proliferation and altered cell cycle progression in a model human hair follicle, possibly due to off-target kinase inhibition.

This study reports that 71% of patients treated with the gamma-secretase inhibitor PF-03084014 for desmoid tumors experienced dermatologic side effects, such as follicular lesions and pruritic eruptions, which were managed with topical or systemic treatments.

This review discusses trichotillomania's clinical features, prevalence, and treatment options, highlighting the potential benefits of behavior therapy and pharmacotherapy but reports no new clinical findings.

This study found that a lacticin 3147 solid lipid nanoparticle gel demonstrated potent and sustained antimicrobial activity against S. aureus, including MRSA, in ex vivo S. aureus-infected pig skin.

This study found that inhibiting mTORC1 activity with rapamycin increased both hair growth and pigmentation in human scalp hair follicles, suggesting a potential strategy for treating greying and hair loss.

This review discusses trichotillomania, its diagnosis, prevalence, potential brain abnormalities, and current treatment options, and offers no new clinical findings.

This review discusses metformin's use in women with polycystic ovary syndrome, focusing on benefits during pre-conception and pregnancy, but reports no new clinical results.

This study found that the CDK4/6 inhibitor palbociclib may protect human hair follicles from the damaging effects of taxane chemotherapy by inducing G1 arrest in stem/progenitor cells.

This study identified molecular differences between dysplastic nevi and common melanocytic nevi, including altered keratinocyte differentiation, increased hair follicle-related molecule expression, and distinct immune microenvironment characteristics in dysplastic nevi.

This study found that increased PHGDH expression in mice led to earlier melanin and melanocyte presence in hair follicles but did not induce cancer.

In this study, long-term use of finasteride did not negatively impact bone mineral density in men with benign prostatic hyperplasia over a 4-year period.

This study demonstrates that dermal white adipose tissue regulates human hair growth and pigmentation through hepatocyte growth factor secretion, highlighting potential therapeutic targets for hair-related disorders.

This study investigated immune dysregulation in individuals with Down syndrome and found that treatment with the JAK inhibitor tofacitinib improved skin conditions like alopecia areata and reduced autoimmune markers without severe side effects. Additional research is necessary to understand its broader impacts.

In this study with organ-cultured human scalp hair follicles, high mTORC1 activity correlated with gray/white hair and reduced pigmentation, while inhibiting mTORC1 with rapamycin increased hair growth and pigmentation, suggesting mTORC1 inhibition could be a strategy for treating hair depigmentation and loss.

This study observed that individuals with Down syndrome exhibit early immune dysregulation, including multi-organ autoimmunity and hypercytokinemia, and found that the JAK inhibitor tofacitinib showed a good safety profile and reduced skin pathology in a Phase II trial.

This paper reports insights from an Expert Panel convened by the Society for Immunotherapy of Cancer on managing immune-related adverse events (irAEs) following immune checkpoint inhibitor therapy, highlighting surveillance gaps and the need for a comprehensive irAE registry to improve post-treatment care for cancer survivors.

This phase I study found that MK-2206 was well tolerated and demonstrated evidence of AKT signaling blockade in patients with advanced solid tumors, with the maximum-tolerated dose established at 60 mg.

This study suggests that seborrhoeic folliculitis may represent a unique form of cicatricial alopecia, linking chronic scalp dermatitis-folliculitis with low-grade inflammatory fibrosing alopecia.

Some oils can penetrate hair and reduce the stickiness between fibers, but mineral oil cannot.

No genetic link between prostaglandins and hair loss found.

This article has no abstract available, so it presents no findings or conclusions.

This study reports that NIH PCOS is linked to more severe metabolic issues, including higher obesity and insulin resistance, compared to non-NIH PCOS phenotypes.

This review discusses various strategies to enhance drug delivery through the skin barrier, highlighting liposomes as promising carriers for increased dermal concentrations in topical therapies, but reports no new research results.

This review discusses the historical and modern use of silver for reducing infections and aiding healing in burns, wounds, and medical devices, noting its benefits and limitations in various applications.

This review examines the pharmacological evidence and bioactive compounds in Hibiscus plants, supporting their potential importance for developing treatments for chronic and degenerative diseases, though more research is needed.