14 citations
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May 2016 in “International Journal of Molecular Sciences” This study showed that knocking out the Ppp2ca gene in the epidermis of mice led to significant hair loss and disrupted hair follicle morphogenesis and regeneration.
12 citations
,
June 2023 in “Journal of trace elements in medicine and biology” This study identified dose levels of selenium that can produce toxicity, noting that doses as low as 2-3 µg Se/kg bw/day can lead to adverse effects, and a human mortality study linked 300 µg/day consumption to increased death risk.
12 citations
,
December 2011 2 citations
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February 2021 in “FEBS open bio” In this study, transfection experiments showed that mutations in the K85 gene affect filament formation with K35, which may impact hair formation related to ectodermal dysplasia.
December 2023 in “Pharmaceutics” In this study, nanoparticles developed with Minoxidil-loaded thiolated β-CDs showed promise for topical scalp use, as they significantly improved drug retention on hair and displayed no irritation in rabbits.
September 2020 in “Journal of Mind and Medical Sciences” This study reported that using a Cutera Xeo laser with specific probes may help treat rosacea symptoms like diffuse facial erythema and telangiectasias, with some risks like bruises and hypopigmentation.
March 2009 in “Dermatology Online Journal” This study reports that blocking the epidermal growth factor receptor in cancer treatments can lead to changes in hair growth and create a "wavy" hair phenotype in some patients.
94 citations
,
January 2007 in “Cutaneous and Ocular Toxicology” This review discusses the long-term cutaneous and ocular complications from sulfur mustard exposure in the Iranian population, identifying pruritus and malignant changes as significant issues and highlighting eye surface damage leading to visual decline.
27 citations
,
April 2004 in “Biochemical and Biophysical Research Communications” In this study, two novel clusters of keratin-associated protein genes on human chromosome 11 were analyzed, suggesting their products are crucial for hair formation due to preferential expression in hair roots.
16 citations
,
September 1999 in “Journal of Investigative Dermatology Symposium Proceedings” 15 citations
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October 1936 in “Archives of Dermatology” This article reviews the role of sulfhydryl compounds, particularly cystine, in sulfur metabolism and the physiology of skin in both normal and pathological conditions, reporting no new findings.
14 citations
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November 2015 in “Annals of the New York Academy of Sciences” This review discusses dietary manipulation strategies in a mouse model of CBS deficiency and reports no new results; the authors emphasize the importance of understanding gene-diet interactions.
14 citations
,
March 2014 in “Experimental and Molecular Pathology” This study found that sulfur mustard affects hair follicles and sebaceous glands in the skin by causing cellular damage, inflammation, and disrupting wound healing processes in hairless mice.
11 citations
,
January 1989 This case report describes two patients with trichothiodystrophy who exhibited a different pattern of hair protein composition changes, suggesting a subgroup of TTD characterized by partial loss of high-sulfur proteins without significant alteration in their amino acid composition.
7 citations
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January 1966 in “Archives of Dermatology” The method accurately measures hair growth with minimal risk and is better than other methods.
6 citations
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March 2009 in “BMC Public Health” In this study, higher levels of the sulfur-containing gas CH3SCH3, associated with oral malodor, were linked to MPB in elderly Japanese males, particularly when gastrointestinal and metabolic disorders were present.
2 citations
,
November 1973 in “PubMed” This study found that autoradiographs of hair can serve as an index of prior /sup 35/S-sodium sulfate exposure in individuals treated for chondrosarcoma.
2 citations
,
January 1968 in “PubMed” This study found that X-irradiation causes hair dysplasia through two mechanisms influenced by oxygen, and cystamine injections after irradiation enhance this effect.
1 citations
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January 2007 in “中国科学通报:英文版” Women's hair has more sulfur, and black hair has more calcium than white hair.
1 citations
,
August 2021 in “Frontiers in Genetics” This study suggests that melatonin may enhance wool growth in cashmere goats by activating sulfur metabolism genes and high-sulfur protein genes, which are crucial for providing sulfur-containing amino acids needed for wool quality.
February 2025 in “Buletin Veteriner Udayana” In this case report, the 14-day treatment with ivermectin, sulfur baths, antihistamines, and supplements resulted in significant recovery in a cat with scabies and sporotrichosis, except for persistent alopecia on the ear pinna. The authors recommend maintaining a clean environment to prevent reinfection.
July 2023 in “Jurnal Ilmu Kesehatan Hewan” In this case report, a 2-month-old dog with scabies showed improvement in skin condition and reduced mite presence 24 days after treatment with simparica, sulfur-based soap, and various topical and oral therapies.
This study found that exposure to Prussian Blue caused significant detachment of cuticle segments from the hair shaft in both new and aged human hairs.
April 2024 in “Advances in Redox Research” In this study, researchers found that polysulfides in human hair keratin contribute to hair strength and antioxidant capacity, with sulfur supplementation enhancing hair strength and cuticle structure amid oxidative stresses such as UV radiation.
February 2024 in “Buletin Veteriner Udayana” In this case report, treatment with ivermectin, antihistamines, vitamin B complex, and sulfur soap reduced skin lesions and itching in a 5-month-old dog diagnosed with demodecosis after 14 days.
100 citations
,
December 2002 in “Journal of biological chemistry/The Journal of biological chemistry” This study identified a domain on human chromosome 21q22.1 containing various high glycine-tyrosine and high sulfur keratin-associated protein genes, revealing their diverse expression in hair-forming cells.
98 citations
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June 2001 in “Journal of biological chemistry/The Journal of biological chemistry” This study identified a cluster of genes on chromosome 17 related to hair keratin-associated proteins, including 37 genes forming seven multigene families, localized in the hair shaft's upper cortex.
62 citations
,
January 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified 16 novel high sulfur KAP genes and two KAP pseudogenes on chromosome 21q23, showing expression in a specific region of the hair fiber cuticle.
48 citations
,
November 2002 in “Journal of biological chemistry/The Journal of biological chemistry” In this study, researchers found that size polymorphisms in certain hKAP1 genes are linked to the hKAP1.1B and hKAP1.3 genes, arising from intragenic deletions and duplications in Japanese and Caucasian populations.
32 citations
,
January 1966 in “Archives of Dermatology” This study found that using sulfur 35 L-cystine for measuring linear hair growth is accurate, cosmetically acceptable, and safe in both experimental animals and humans.