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The document highlights various patents for new compounds with potential treatments for multiple diseases, including cancer, hormonal disorders, and diabetes.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Minoxidil treats hair loss, promotes growth, has side effects, and has recent patents.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Diazoxide, minoxidil sulphate, and cromakalim relax rat blood vessels by opening K+ channels, with some differences in their actions.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

Androgen conjugates might be better indicators of skin sensitivity to hormones in women with excessive hair growth.

Hair loss in balding individuals is linked to changes in specific hair growth-related genes.

Thyroid hormone affects skin health, with too little causing rough, pale skin and too much leading to smooth, thin skin, and may also impact wound healing and skin conditions.

Low-dose oral minoxidil safely treats hair loss, with hypertrichosis as main side effect.

The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.

Potassium channel openers like minoxidil help hair grow by acting on hair follicles.

Thyroid hormones are important for skin health and might help treat skin diseases, but more research is needed to understand their effects fully.

Higher minoxidil doses in dogs cause faster heart rate, lower blood pressure, and heart issues.

Sp6 promotes tooth development by reducing follistatin levels.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

Older rats more affected by minoxidil's cardiotoxic effects than younger rats.

Understanding hair follicle biology and stem cell control could lead to new hair loss treatments.

Over 67 genes linked to ichthyosis help improve diagnosis and treatment.

The enzyme PST is found in developing human kidneys and helps with detoxification and development.

Minoxidil helps protect and rebuild elastic fibers in arteries, improving artery function, especially in older females.

The document concludes that oral finasteride and topical minoxidil are effective for genetic hair loss, while other treatments for different types of hair loss show promise but need more research.