12 citations
,
January 2011 in “Journal of the Saudi Society of Dermatology & Dermatologic Surgery” This study documented an outbreak of thallium poisoning in Iraq, highlighting its dermatological, neurological, and psychological signs, which are crucial for accurate diagnosis.
11 citations
,
January 2023 in “World Journal of Clinical Cases” This study suggests that idiopathic hirsutism may involve higher local androgen synthesis despite normal serum androgen levels, challenging its categorization as idiopathic.
11 citations
,
August 2014 in “PubMed” This study found that women with acne had higher rates of hyperandrogenism and obesity, and higher androgen levels and BMI were linked to increased acne severity.
11 citations
,
January 2013 in “Indian Journal of Endocrinology and Metabolism” This case study describes an extremely rare instance of androgen-secreting adrenocortical carcinoma in a patient with non-classical congenital adrenal hyperplasia.
11 citations
,
August 2010 in “Developmental neurobiology” This study suggests that Ptprq in the hair bundles may exist as multiple isoforms that are differentially expressed throughout development and affect the organization of stereocilia in the chick inner ear.
10 citations
,
May 2021 in “Psychoneuroendocrinology” This study suggests that circulating androgens produced by the testes have limited clinical relevance to major depressive disorder in adult men, but certain androgens may be linked to specific MDD symptoms.
10 citations
,
January 2015 in “Journal of Dermatology and Dermatologic Surgery” In this study, telogen effluvium was commonly found to be associated with iron-deficiency anemia and hypothyroidism among female patients in Makkah, Saudi Arabia.
9 citations
,
June 2014 in “European Journal of Obstetrics & Gynecology and Reproductive Biology” Blood AMH levels are higher in women with PCOS than in those with other similar conditions.
9 citations
,
March 2008 in “PubMed” This study observed that women with female pattern hair loss had a significantly lower ratio of estradiol to free testosterone compared to healthy controls, suggesting a potential hormonal trigger for hair loss.
9 citations
,
January 1999 in “Dermatology” This hypothesis paper proposes that men with X-linked recessive ichthyosis may exhibit no androgenetic alopecia or only mild forms, and suggests clinical studies to evaluate this hypothesis.
9 citations
,
December 1991 in “Annals of the New York Academy of Sciences” Minoxidil helps hair growth by increasing blood flow and stimulating hair follicles.
8 citations
,
July 1980 in “Archives of Dermatology” This report suggests that clinically inapparent sweat gland tumors might cause scalp hair loss, as seen in a case of a 57-year-old woman with progressive hair thinning.
7 citations
,
February 2017 in “The American journal of medicine” This case report describes a 34-year-old woman who, after Roux-en-Y gastric bypass surgery, experienced improvements in symptoms of dizziness and energy following treatment with oral ferrous sulfate for iron deficiency.
7 citations
,
January 1992 in “Skin Pharmacology and Physiology” This study found that minoxidil accumulated in pigmented hair follicle cells more than in unpigmented ones, but this targeting by pigmentation did not affect hair growth.
6 citations
,
March 2019 in “The American Journal of Dermatopathology” This report describes three cases of LC-associated amyloidosis presenting with alopecia, highlighting its potential mimicry of androgenetic alopecia or alopecia areata without systemic amyloidosis.
6 citations
,
January 2019 in “Indian Journal of Pharmacology” In this case study, a 14-year-old female with premature hair graying showed improved hair color after treatment with a topical Melitane 5% formulation and oral hair supplements.
6 citations
,
July 2018 in “DOAJ (DOAJ: Directory of Open Access Journals)” This case study reports the first known instance of hepatic adrenocortical carcinoma in a virilized young woman, highlighting the importance of comprehensive evaluation to identify ectopic adrenal tumors.
6 citations
,
April 2017 in “JAMA Dermatology” This study concluded that visits to emergency and urgent care centers for severe sunburn treatment are largely avoidable and contribute to significant healthcare costs.
6 citations
,
January 2017 in “Dermato-endocrinology” This study found that androsterone glucuronate (ADT-G) was the only androgenic metabolite sensitive to detecting differences between adult women with acne and controls, and its levels decreased with systemic treatment.
6 citations
,
January 2016 in “Open journal of regenerative medicine” This study found that macrophages treated with keratin in vitro were more similar to anti-inflammatory M2 macrophages and reduced astrocyte reactivity, potentially limiting secondary inflammatory damage after spinal cord injury.
6 citations
,
January 2003 in “Dermatology” This study reviewed 26 cases of X-linked recessive ichthyosis and observed 11 patients with advanced-stage androgenetic alopecia, suggesting a compensatory role of two steroid biosynthesis pathways.
6 citations
,
January 2000 in “The Journal of Trace Elements in Experimental Medicine” In this study, an 11-year-old girl with acrodermatitis enteropathica showed significant improvement in symptoms after oral zinc therapy.
5 citations
,
March 2010 in “Gynecologic and obstetric investigation” This study found that parenteral administration of cyproterone acetate was more effective than high-dose oral treatment in reducing facial hair diameter and improving dermatological parameters in patients with severe hirsutism, despite similar androgen suppression.
5 citations
,
March 2009 in “Skin Pharmacology and Physiology” This study found that DNA flow cytometry effectively evaluates physiological and hormonal influences on cell cycle kinetics of human anagen hair bulbs, with increased S phase cells observed in male pattern baldness, hirsutism, and hyperthyroidism.
5 citations
,
December 2004 in “Dermatology” This review describes two cases of young women with primary amenorrhea and hyperandrogenemia, suggesting that adrenal tumors should be considered in patients with significantly elevated circulating testosterone levels.
4 citations
,
October 2022 in “Evidence-based complementary and alternative medicine” This study found that Ficus carica extract enhanced fertility markers, including hormone levels and reproductive organ activity, in rats of both sexes, suggesting potential benefits for managing fertility issues.
4 citations
,
May 2019 in “PubMed” This study reported that the expression of sulfotransferase enzymes in hair follicles remained stable during treatment with topical minoxidil, indicating consistent metabolic activity throughout the treatment period.
4 citations
,
January 2019 in “PubMed” This study found that women with female pattern hair loss had significant hormonal imbalances, specifically involving adrenal androgens, suggesting these may play a central role in the condition's development.
4 citations
,
November 2018 in “Journal of Pharmaceutical and Biomedical Analysis” This study found that a hydro-alcoholic extract of Roselle petals may reduce free radical production during UV-induced photodecomposition of antibiotics, potentially offering protective benefits for patients using similar topical antibiotics.
4 citations
,
November 2013 in “Journal of IMAB - Annual Proceeding (Scientific Papers)” This report presents a case of functioning adrenocortical oncocytoma in a 9-year-old girl with virilization symptoms, successfully treated with laparoscopic surgery.