February 2013 in “Journal of the American Academy of Dermatology” Iron supplements may reverse premature hair graying caused by iron deficiency.
January 2011 in “Reactions Weekly” St. John's Wort may reduce the effectiveness of finasteride by increasing its breakdown in the body.
January 2008 in “Abstracts” Minoxidil sulfate gel can be used to treat hair loss.
This study found that supplementing dog food with zinc methionyl glycinate at 160 ppm improved hair growth rate, zinc levels in plasma and hair, and hair condition more than lower doses or sulfate form.
Minoxidil sulfate, delivered through iontophoresis, can be used to treat hair loss.
January 2004 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found no elevation of serum DHEA-S levels in men with androgenetic alopecia and observed no correlation between DHEA-S levels and the clinical stage of the condition.
January 2001 in “대한피부과학회지” This study found no significant differences in plasma DHEA-S and total testosterone levels between female patients with androgenetic alopecia and normal controls, regardless of clinical type or hyperandrogenic symptoms.
December 2020 in “Journal of Skin and Sexually Transmitted Diseases” This study found no significant correlation between serum testosterone or DHEAS levels and the severity of acne or FPHL in a localized female population, but noted most patients had low testosterone levels.
April 2012 in “Journal of IMAB” This study found no correlation between clinical stages of androgenetic alopecia and serum DHEA-S levels in men, contrasting with previous studies suggesting elevated levels.
October 2004 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found no correlation between the clinical stage of androgenetic alopecia and serum levels of dehydroepiandrosterone-sulfate, contrasting earlier findings and supporting theories about alternative androgen sources in hair follicles.
111 citations
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August 2002 in “Journal of Medicinal Chemistry” This study reports that 2-(1-Adamantyl)-4H-thiochromen-4-on-6-O-sulfamate is the most potent steroid sulfatase inhibitor identified so far, exhibiting 170-fold higher activity than the lead compound estrone sulfamate.
17 citations
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December 2004 in “Bioorganic & Medicinal Chemistry Letters” This study identified N-acyl arylsulfonamides, particularly N-(Boc-piperidine-4-carbonyl)-benzenesulfonamides, as steroid sulfatase inhibitors with improved cellular potency compared to previous compounds.
1 citations
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January 2024 in “Pharmaceuticals” The researchers reported that dPGS-PCL as a carrier improved the penetration of tofacitinib in an ex-vivo human skin model compared to free tofacitinib, but did not show significant differences in inhibiting IL-6 and IL-8 during short incubation.
51 citations
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February 2004 in “Journal of Investigative Dermatology” MCSP may help identify and regulate skin stem cells, affecting hair growth and regeneration.
45 citations
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October 2014 in “Stem cell research & therapy” This study found that using 3D Gel-C6S-HA scaffolds seeded with VEGF165-modified rat hair follicle stem cells enhanced angiogenesis and vascularization in tissue-engineered skin, improving wound healing.
15 citations
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January 1987 in “Electrophoresis” This study found that electrophoretic keratin typing of head hair can identify specific polypeptide patterns, suggesting potential applications in genetic and forensic investigations.
11 citations
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January 1987 in “Electrophoresis” This study found that keratin phenotypes were consistent across different types of hair from the same individual, allowing for successful keratin typing following ABH blood group determination.
5 citations
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August 2014 in “Pharmaceutical Development and Technology” In this study, the researchers reported that while both propylene glycol and sodium lauryl sulfate enhanced finasteride's skin deposition, ethanol was the only effective enhancer of finasteride's permeation through the skin.
1 citations
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January 1972 in “PubMed”
May 2023 in “International Journal of Trichology” In this study, 70% of female androgenetic alopecia patients who did not respond to standard minoxidil experienced clinical improvement after switching to a propylene glycol-free, witch hazel-based 5% minoxidil sulfate solution, with the treatment also being well-tolerated.
This study found that a modified scaffold with VEGF165 genetically modified hair follicle stem cells significantly promoted blood vessel growth and wound healing in rats, suggesting its potential as a skin substitute in clinical settings.
October 2004 in “Australian Prescriber” This discussion reviews the lack of long-term clinical studies on metformin's cardiovascular benefits in women with polycystic ovary syndrome, advocating for lifestyle changes to improve insulin sensitivity.
September 1992 in “Journal of Dermatological Science” 1 citations
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October 2023 in “Pharmaceuticals” In this study, researchers investigated GAGs from the marine invertebrate Microcosmus exasperatus, finding that its polysaccharides possess antitumoral properties without affecting anticoagulant activity. The unique composition shows potential for cancer treatment when combined with existing therapies in future studies.
142 citations
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December 1991 in “Antimicrobial Agents and Chemotherapy” This study reported that continuous intravenous dextran sulfate was toxic and ineffective as a treatment for symptomatic HIV infection, as it did not improve surrogate markers and caused significant side effects.
9 citations
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March 2009 in “Endocrine Practice”
49 citations
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December 2017 in “Journal of pharmaceutical and biomedical analysis” This study developed and validated a high-resolution mass spectrometry method to screen for prohibited substances and analyze six endogenous steroids in urine according to World Antidoping Agency requirements, demonstrating its effectiveness for antidoping analysis.
7 citations
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January 2007 in “Elsevier eBooks” This article reviews the composition and functionality of shampoos, emphasizing the role of surfactants in cleaning and conditioning hair, and reports no new experimental results.
4 citations
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May 2024 in “Steroids” This study developed and validated a comprehensive method using mass spectrometry to profile sex (pro)hormones in plasma, with results showing reliable calibration and detection of 31 analytes in samples from pre- and postmenopausal women and men, while addressing potential over- or underestimations in analyte concentrations.
1 citations
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October 2021 in “Indian Journal of Plastic Surgery/Indian journal of plastic surgery” This study highlights that improving medical professionals' knowledge of hair cosmetics can enhance patient adherence to alopecia treatments and reduce health risks from incorrect use of hair products.