June 2025 in “Clinical and Experimental Dermatology” In this study, the researchers found no link between finasteride use and increased suicide attempt risk among Danish males, noting unadjusted and adjusted odds ratios close to one.
December 2025 in “Neurobiology of Stress” This study found that individuals with a recent history of suicide attempts exhibited altered DHEA hair levels, suggesting possible dysregulation of the HPA axis as a biopsychosocial feature, and recommends further investigation into hair hormones as potential markers of suicidal crisis and vulnerability.
August 2018 in “Journal of The American Academy of Dermatology” November 2007 in “Hospital pharmacy” This article discusses the importance of increasing awareness about specific adverse drug reactions, prevention methods, and the promotion of reporting ADRs to the FDA's MEDWATCH program; it reports no new results.
July 2026 in “Journal of the American Academy of Dermatology” Finasteride may lower depression risk in younger men with hair loss but increase it in older men with prostate issues.
August 2018 in “Journal of The American Academy of Dermatology” Finasteride use for hair loss is linked to an increased risk of suicidal thoughts and a higher risk of suicide.
August 2018 in “Journal of The American Academy of Dermatology” Finasteride, a hair loss drug, is linked to increased suicidal thoughts, particularly when used for hair loss.
August 2018 in “Journal of The American Academy of Dermatology” The conclusion is that finasteride is linked to an increased risk of suicidal thoughts and a higher risk of completed suicide when used for hair loss.
November 2021 in “Evidencia” In this study, the use of finasteride in young patients may be linked to a higher risk of anxiety, depression, and suicide-related adverse events.
1 citations
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January 2007 in “The Kitakanto Medical Journal” This report documents a case where a man survived sub-acute toxicity from an overdose of the anticancer drug UFT due to effective treatment with antibiotics and granulocyte colony-stimulating factor.
6 citations
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November 1999 in “Psychiatric services” This case report describes a woman who experienced complete but temporary scalp hair loss after a massive overdose of divalproex, suggesting a potential acute side effect of the drug.
116 citations
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December 2013 in “The Journal of Pediatrics” This study reported that treatment with gonadotropin-releasing hormone analogs and cross-sex hormones appears appropriate for carefully selected youth with gender dysphoria, but long-term safety needs further investigation.
16 citations
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January 2019 in “Kansas journal of medicine” This source outlines what it takes to be a competent provider for transgender individuals, focusing on their health needs, disparities, and coverage, and examines medical biases and hormone treatment guidelines, alongside treatment options for different age groups, concluding with evolving trends in medical education.
October 2014 in “Archives of disease in childhood” This study found that parents of children with cancer experienced significant somatic health issues during and after their child's treatment, with increased complications reported after treatment.
14 citations
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November 2011 in “Journal of The American Academy of Dermatology” This discussion highlights that alopecia areata incognita is challenging to diagnose and treat, with systemic corticosteroids potentially leading to remission when local treatments fail.
5 citations
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January 2012 in “Psychology” This study observed that individuals with major unipolar depression have higher levels of sodium and potassium in their hair and decreased antidiuretic hormone levels, similar to changes seen in astronauts after space missions.
This study found that depressed individuals had higher levels of sodium and potassium in their hair and lower antidiuretic hormone levels, similar to changes observed in weightless conditions experienced by astronauts.
6 citations
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January 2020 in “Dermatology” This study suggests that men under 40 who develop persistent sexual side effects and insomnia after using finasteride for alopecia may be at increased risk of suicide.
12 citations
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April 2018 in “Physiology & Behavior” In this study, clozapine reduced suicide-related behaviors in a schizophrenia-like mouse model, but its effects on exploratory behavior were counteracted by the neurosteroid inhibitor finasteride.
25 citations
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September 2024 in “Cardiovascular Drugs and Therapy” This study found that while glucagon-like peptide 1 receptor agonists report more incidents of suicide, hair loss, and aspiration compared to some other antidiabetic drugs, they did not meet the threshold for positive safety signals.
December 2022 in “JAMA network open” This study found that men using 5-alpha-reductase inhibitors showed an increased risk for dementia shortly after starting treatment, which diminished over time, and a consistent association with depression, but no link to suicide.
67 citations
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August 2013 in “International Journal of Cosmetic Science” This review discusses the role of oxidative stress in hair greying and suggests that understanding melanocyte susceptibility at different follicular locations may help develop therapies for preventing and reversing the process; it reports no new experimental results.
March 2025 in “Journal of Cosmetic Dermatology” This study found that reports of suicidal ideations linked to oral finasteride were significantly higher in 2013–2018 and 2019–2023 compared to 2006–2011, potentially due to increased awareness of post-finasteride syndrome from 2012 onward. No such signals were seen with oral dutasteride.
December 2025 in “Journal of Cosmetic Dermatology” This study found that finasteride use is not significantly associated with an increased risk of depression or suicide, based on Mendelian randomization analysis and COX regression analysis in a large UK Biobank cohort.
June 2026 in “The Pharmacogenomics Journal” September 2025 in “Therapies” This study found that finasteride is associated with significant depressive effects, including an increased risk of suicidality, which can persist beyond 20 months after stopping the medication, even without prior sexual dysfunction or psychiatric history.
June 2025 in “Cermin Dunia Kedokteran” This study emphasizes the importance of early detection and cross-sector collaboration in preventing suicide among adolescents, highlighting the role of health professionals, screening tools, and family support systems.
90 citations
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March 2017 in “JAMA Internal Medicine” In this study, older men using 5α-reductase inhibitors for prostatic enlargement did not show increased risk of suicide, but had elevated risks of self-harm and depression.
January 2021 in “Social Science Research Network” This review discusses the ethical and legal challenges faced by practitioners who conscientiously object to participating in euthanasia and assisted suicide, reporting no new clinical results.
April 2026 in “Brain Sciences” This pharmacovigilance study analyzed FAERS data and found that finasteride is more frequently associated with neuropsychiatric reactions like depression and suicide risk, especially in younger men using it for alopecia, compared to dutasteride.