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Melatonin may benefit skin health and could be a promising treatment in dermatology.

Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

Oral minoxidil promotes hair growth but may cause side effects; needs monitoring.

Metformin and rosiglitazone improve blood vessel function in women with PCOS, with metformin also reducing insulin resistance and testosterone levels.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

Spironolactone improved blood vessel function and cholesterol levels in non-obese women with PCOS.

Foxi3 expression in developing teeth and hair is controlled by the ectodysplasin pathway.

Bariatric surgery may help severely obese teenagers but has risks and requires careful patient selection and long-term care.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Scientists have made progress in creating replacement teeth, hair, and glands that work, which could lead to new treatments for missing teeth, baldness, and dryness conditions.

New resveratrol-related compounds show promise for treating various health issues but need more research for clinical use.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

New drugs and combination therapies are improving treatment for lower urinary tract symptoms.

The document concludes that there are still unknowns about the effectiveness, risks, and detection of performance-enhancing drugs, and doping remains a challenge.

Early medical support for transgender youth is important for their health, with low regret for gender-affirming hormone use and a need for knowledgeable care providers.

Hair in mammals likely evolved from glandular structures, not scales.

FPHL is common in women, influenced by genetics and hormones, and can be treated with medications, laser therapy, or hair transplantation.

Oral minoxidil improves hair density in women with androgenetic alopecia, with mild side effects.

Primary care doctors should address female sexual dysfunctions to improve women's sexual health and life quality.

The conclusion is that there is a high demand for new contraceptives that provide both pregnancy prevention and protection against STIs, along with additional health benefits.

The document concludes that regenerating functional ectodermal organs like teeth and hair is promising for future therapies.

PSA levels could help detect illegal steroid use in female athletes but face challenges like cost and PCOS prevalence.

Hair transplantation is effective for baldness, with new methods improving results, but staying updated is crucial for patient outcomes.

Testosterone is crucial for development, growth, and various body functions in mammals.

Low-level laser therapy using near-infrared light may help heart conditions and promote healing by releasing nitric oxide.

The document concludes that gender-affirming treatments are essential for transgender individuals and outlines safe hormone therapy practices.