research A Randomized Placebo-Controlled Study on the Effects of Pioglitazone on Cortisol Metabolism in Polycystic Ovary Syndrome
Pioglitazone improved insulin sensitivity and altered cortisol metabolism in PCOS patients.
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research Incorporation Of Finasteride-Loaded Microspheres Into Personalized Microneedle For Sustained Transdermal Delivery
The new microneedle system safely delivers finasteride through the skin to treat hair loss.
research Reduction of Intrafollicular Apoptosis in Chemotherapy-Induced Alopecia by Topical Calcitriol Analogs
Topical calcitriol-analogs can reduce hair loss caused by chemotherapy.
research Evaluation of Hair Growth Promoting Activity of Phyllanthus Niruri
Phyllanthus niruri extract may help treat hair loss by promoting hair growth and blocking a hair loss-related enzyme.
research Reconsidering PCOS Etiology, Diagnosis, Clinical Subgroups, and Subgroup-Specific Treatments
Different types of PCOS need specific diagnosis methods and treatments.
research A Guide to the Use of Bioassays in Exploration of Natural Resources
Bioassays help find useful compounds in nature for making medicines, supplements, and cosmetics.
research First-In-Man Clinical Trial of the Oral Pan-AKT Inhibitor MK-2206 in Patients With Advanced Solid Tumors
MK-2206 was safe and effectively blocked AKT signaling in cancer patients, warranting more trials.
research Human Peptidylarginine Deiminase Type III: Molecular Cloning and Nucleotide Sequence of the cDNA, Properties of the Recombinant Enzyme, and Immunohistochemical Localization in Human Skin
PAD3 plays a key role in hair and skin protein structure and may be linked to skin diseases.
research Impaired Notch-MKP-1 Signalling in Hidradenitis Suppurativa: An Approach to Pathogenesis by Evidence from Translational Biology
Faulty Notch signalling may cause hair follicle changes and inflammation in hidradenitis suppurativa.
research Bone-Forming Cells with Pronounced Spread into the Third Dimension in Polymer Scaffolds Fabricated by Two-Photon Polymerization
Bone-forming cells grow well in 3D polymer scaffolds with 35 µm pores.
research Toxicology and Pharmacology of Botulinum and Tetanus Neurotoxins: An Update
Botulinum and tetanus neurotoxins are better understood now, with updated information on their effects and treatment.
research Interleukin-6 from Adipose-Derived Stem Cells Promotes Tissue Repair by Increasing Cell Proliferation and Hair Follicles in Ischemia/Reperfusion-Treated Skin Flaps
IL-6 from stem cells helps repair skin and grow hair.
research The Beneficial Effects of Chick Embryo Extract Preconditioning on Hair Follicle Stem Cells: A Promising Strategy to Generate Schwann Cells
Chick embryo extract helps rat hair follicle stem cells potentially turn into Schwann cells, important for the nervous system.
research Malate-Based Polyester Chemically Shielded Metal-Phenolic Networks Coated Artificial Hair Fibers With Long-Lasting Antimicrobial And Anti-Inflammatory Performance
research Electrospun 3D Nanofibrous Materials and Their Applications in Orthopaedics
Electrospun 3D nanofibrous materials show promise for bone regeneration in orthopaedics.
research Recent Progress of Polymeric Microneedle-Assisted Long-Acting Transdermal Drug Delivery
Polymeric microneedles offer a less invasive, long-lasting drug delivery method that improves patient compliance and reduces side effects.
research Optimization of Bear Oil Extraction Process and Hair Growth Activity
Enzymatically extracted bear oil has more unsaturated fats and significantly increases hair growth in mice.
research Spatiotemporal Expression and Haplotypes Identification of KRT84 Gene and Their Association with Wool Traits in Gansu Alpine Fine-Wool Sheep
The KRT84 gene is linked to better wool quality in Gansu Alpine Fine-wool sheep.
research Development of a Novel In Vitro Strategy to Understand the Impact of Shaving on Skin Health: Combining Tape Strip Exfoliation and Human Skin Equivalent Technology
The method effectively mimics shaving damage on skin for testing skincare products.
research 3D Bioprinting in Plastic and Reconstructive Surgery: Current Concepts, Progress, and Clinical Application
3D bioprinting is advancing in plastic and reconstructive surgery, especially for creating tissues and improving surgical planning, but faces challenges like vascularization and material development.
research A Bio-Functional Wnt3a Gradient Microarray for Cell Niche Studies
The study created a tool that mimics natural cell signals, which increased cell growth and could help with hair regeneration research.
research Enzymes
Enzymes play crucial roles in metabolism, health, and disease management.
research Effects of KRTAP20-1 Gene Variation on Wool Traits in Chinese Tan Sheep
Variant G of the KRTAP20-1 gene improves wool curliness in Chinese Tan sheep.
research A Review of Keratin-Based Biomaterials for Biomedical Applications
Keratin from hair and wool is used in medical materials for healing and drug delivery.
research The JAK/STAT Signaling Pathway: From Bench to Clinic
The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
research Activating an Adaptive Immune Response from a Hydrogel Scaffold Imparts Regenerative Wound Healing
Hydrogel scaffolds can help wounds heal better and grow hair.
research Spermidine/Spermine-N1-Acetyltransferase: A Key Metabolic Regulator
SSAT is a key enzyme affecting cell growth and metabolism, with potential but risky use in disease treatment.
research Understanding, Recognizing, and Managing Toxicities of Targeted Anticancer Therapies
Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.
research O-Glycosylated Cell Wall Proteins Are Essential in Root Hair Growth
Proteins with added sugars are crucial for plant root hair growth.
research Nanoparticle-Based Targeting of Vaccine Compounds to Skin Antigen-Presenting Cells by Hair Follicles and Their Transport in Mice
Nanoparticles can deliver vaccines through hair follicles, triggering immune responses and providing protection.