research Dihydrotestosterone-Inducible Dickkopf 1 from Balding Dermal Papilla Cells Causes Apoptosis in Follicular Keratinocytes
A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.
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research Allergic Contact Dermatitis from Glycerin in a Moisturizing Cream
Glycerin in hand cream can cause allergic skin reactions.
research Flavonoid 4,4'-Dimethoxychalcone Selectively Eliminates Senescent Cells Via Activating Ferritinophagy
The substance DMC helps get rid of aging cells by triggering a process that causes cell death, which could treat age-related diseases.
research Discovery Of A Novel And Highly Selective JAK3 Inhibitor As A Potent Hair Growth Promoter
MJ04, a new compound, effectively promotes hair growth and is a potential topical treatment for hair loss.
research Androgen Excess: Investigations and Management
The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.
research Acne Vulgaris
Acne vulgaris is a common skin condition that can cause low self-esteem and depression, and early treatment is important to prevent scarring.
research Induction of Psoriasiform Changes in Guinea Pig Skin by Propranolol
Propranolol combined with injections caused skin changes in guinea pigs but didn't fully mimic psoriasis.
research Tumor Necrosis Factor in Sepsis
Topical eye β-blockers might cause hair loss, which usually gets better after stopping the medication.
research MicroRNA-1246 Inhibits NFATc1 Phosphorylation and Regulates T Helper 17 Cell Activation in the Pathogenesis of Severe Alopecia Areata
A substance called miR-1246 may help treat severe hair loss by reducing certain immune cell activities.
research Ischemic Skin Flaps: What to Use to Save Them? A Narrative Review
Various substances, quitting smoking, and certain topical applications can enhance the survival of skin flaps used in surgery. Oxygen-free radicals play a role in tissue injury, but certain treatments can have beneficial effects.
research Determination of Permeation Pathway of Gentamicin into Pig's Ear Skin
Gentamicin penetrates pig skin better through open hair follicles than blocked ones.
research Comparison of the Therapeutic Effect of Allogeneic and Xenogeneic Small Extracellular Vesicles in Soft Tissue Repair
Both human and animal-derived small extracellular vesicles speed up skin healing equally well.
research Current Prospective in the Management of Depression Using Off-Label Drugs and Advanced Drugs
New medications are improving depression treatment, emphasizing accurate diagnosis and chronic care.
research Anti-Androgens for the Treatment of Hirsutism
Different anti-androgen medications can help treat excessive hair growth, but the right choice depends on accurate diagnosis.
research Skin Lesions in Drug Addicts
Drug addicts often have scars, skin color changes, blocked veins, and bruising, with severe ulcers from barbiturate injections.
research Alopecia Secondary to Hyaluronic Acid Embolization: Trichoscopic Findings
Hyaluronic acid injections can cause hair loss due to blocked blood vessels.
research Fabrication and Characterization of Dissolving Microneedles Containing Oryza Sativa L. Extract Complex for Enhancement of Transfollicular Delivery
The P25H5-O microneedles effectively deliver substances through hair follicles and are safe for skin cells.
research A Thallium-Based Screening Procedure to Identify Molecules That Modulate the Activity of Ca2+-Activated Monovalent Cation-Selective Channels
The conclusion is that a new test was created to find substances that affect specific ion channels, and it works well for drug discovery.
research Diphlorethohydroxycarmalol, Isolated from Ishige Okamurae, Increases Prostaglandin E2 through the Expression of Cyclooxygenase-1 and -2 in HaCaT Human Keratinocytes
A compound from brown algae boosts the production of a certain inflammatory substance in skin cells.
research Caffeine’s Mechanisms of Action and Its Cosmetic Use
Caffeine in cosmetics may reduce cellulite, protect skin, and stimulate hair growth, but more research is needed on its use and effects.
research Finasteride Inhibits the Progesterone-Induced Spike-Wave Discharges in a Genetic Model of Absence Epilepsy
Finasteride blocks progesterone's effect on absence seizures in rats.
research Minoxidil in the Management of Intractable Hypertension
Minoxidil significantly lowers blood pressure in patients with hard-to-treat hypertension, but can cause fluid retention and excessive hair growth.
research Novel Anti-Melanogenesis Properties of Polydeoxyribonucleotide, a Popular Wound Healing Booster
Polydeoxyribonucleotide (PDRN) may help lighten skin and treat hyperpigmentation.
research Effect of Citral on Experimentally Induced Comedones
1% citral is more effective for treating comedone acne than salicylic acid.
research Topical Antiandrogens
Topical antiandrogens might treat skin issues like hair growth, balding, and acne, but finding effective treatments without side effects is challenging.
research Human Hair Follicle: Reservoir Function and Selective Targeting
The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.
research Sterol Intermediates of Cholesterol Biosynthesis Inhibit Hair Growth and Trigger an Innate Immune Response in Cicatricial Alopecia
Cholesterol-related compounds can stop hair growth and cause inflammation in a type of scarring hair loss.
research Norgalanthamine Stimulates Proliferation of Dermal Papilla Cells via Anagen-Activating Signaling Pathways
Norgalanthamine helps hair cells grow by activating certain pathways related to hair growth.
research In Silico Study on the Contribution of the Follicular Route to Dermal Permeability of Small Molecules
Hair follicles affect how well small molecules can pass through the skin, and this varies depending on the molecule's features.
research Advancing Skin Model Development: A Focus on a Self-Assembled, Induced Pluripotent Stem Cell-Derived, Xeno-Free Approach
A new ethical skin model using stem cells offers a reliable alternative for dermatological research.