78 citations
,
June 1989 in “The Journal of dermatologic surgery and oncology” This article reviews acne keloidalis in young black men, describes its clinical and histopathological characteristics, and highlights surgical therapy approaches despite the uncertain etiology of the condition.
17 citations
,
September 2012 in “Dermatologic Clinics” This review discusses histologic findings in alopecia and emphasizes the importance of understanding normal follicular anatomy and cycles in transverse sections, without reporting new results.
22 citations
,
January 2018 in “Experimental Dermatology” This article reviews insights into the pathogenesis of primary cicatricial alopecias, such as lichen planopilaris, provided by emerging technologies, but it does not report new clinical results.
98 citations
,
May 2008 in “British Journal of Dermatology” This review discusses evidence-based guidance for managing primary cicatricial alopecias but reports no new clinical results, highlighting significant gaps in knowledge and the need for more quality trials.
122 citations
,
April 1995 in “Journal of Cutaneous Pathology” The document describes how to tell different types of non-scarring hair loss apart by looking at hair and scalp tissue under a microscope.
65 citations
,
November 2016 in “Journal of The American Academy of Dermatology” This article reviews various types of primary cicatricial alopecias and emphasizes the importance of accurate diagnosis to improve management strategies, particularly detailing remaining lymphocytic forms and expanding on neutrophilic and mixed types.
March 2026 in “Clinical Cosmetic and Investigational Dermatology” This review discusses current hair removal strategies in paramedian forehead flap reconstruction and reports no new clinical results; it offers recommendations to improve aesthetic outcomes by guiding timing and technique selection.
71 citations
,
January 2015 in “The Scientific World Journal” This review discusses the link between insulin resistance and skin conditions such as acanthosis nigricans and psoriasis, but provides no new clinical results.
1 citations
,
January 2019 in “Springer eBooks” Hidradenitis Suppurativa is a chronic skin condition best treated early with surgery for better outcomes and less recurrence.
72 citations
,
November 2000 in “Archives of Dermatology” This study found that excision with primary closure is an effective surgical treatment for extensive acne keloidalis nuchae, with good cosmetic results and minimal recurrence observed among patients.
3 citations
,
August 2020 in “PubMed” This review discusses the potential efficacy and applications of platelet-rich plasma in dermatology, highlighting its use in various skin conditions but reporting no new clinical results; the authors call for standardization of preparation and treatment methods.
6 citations
,
January 2018 in “Journal of Cutaneous and Aesthetic Surgery” This study concluded that ACD-A vials yielded the highest quality and quantity of platelets in platelet-rich plasma for hair rejuvenation compared to EDTA and sodium citrate.
36 citations
,
December 2014 in “F1000 prime reports” This article reviews the challenges in treating hidradenitis suppurativa and discusses potential treatment options, emphasizing the need for increased awareness and comprehensive care, but reports no new clinical results.
30 citations
,
May 2016 in “International Journal of Cosmetic Science” This study found that apoptosis was more prevalent in hair follicles of women with female pattern hair loss, particularly in miniaturized follicles, and was associated with follicular inflammation.
6 citations
,
March 2005 in “Journal of the American Academy of Dermatology” Follicular dystrophy in immunocompromised patients may be linked to medication or viral factors and can improve with treatment changes.
11 citations
,
June 1974 in “Journal of Cutaneous Pathology” In this study, electron microscopy of follicular mucinosis showed severe cytoplasmic degeneration in hair follicles, with myelin figures and onion-like lamellar structures, but no indications of mucin release through degeneration or degradation were found.
11 citations
,
June 1985 in “Journal of cutaneous pathology” This review details pathologic changes in hair follicles, such as infundibular hyperkeratosis and inflammation, but offers no new diagnostic results.
October 2024 in “Journal of Cutaneous Pathology” In this study of folliculitis decalvans, researchers found that compound follicular structures in scalp biopsies are primarily composed of terminal anagen follicles, surrounded by fibrosis and inflammatory cell infiltrate, which could enhance understanding of this condition.
2 citations
,
June 2001 in “American Journal of Pathology” This article explores the complexity and significance of the hair follicle, emphasizing new insights into its biological roles and the involvement of p53 in follicular regression.
100 citations
,
June 2006 in “British Journal of Dermatology” This study found that as hair loss severity increased in women with female pattern hair loss, the number of vellus follicles also rose, indicating miniaturization of terminal hair follicles.
43 citations
,
December 2008 in “Molecular biology of the cell” This study found that disrupting Smad4 signaling in young mice led to overactivation of follicle stem cells, causing hyperplasia and depletion of the stem cell niche.
November 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study in live mice suggests that hair follicle regression involves apoptosis propagation towards stem cells, potentially slowed by a protective signal from the stem cells themselves.
8 citations
,
September 2002 in “Genes to Cells” This study suggests that label-retaining cells in the hair follicle contribute to follicular renewal, indicating a specific role in the hair cycle by proliferating during the late telogen phase.
54 citations
,
December 1999 in “Journal of Investigative Dermatology Symposium Proceedings”
January 2016 in “Journal of The American Academy of Dermatology” This case report describes a 59-year-old woman diagnosed with frontal fibrosing alopecia, presenting with scarring alopecia and perifollicular erythematous papules.
40 citations
,
November 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that different melanocyte subpopulations in hair follicles have varying patterns of apoptosis and survival during the catagen phase, which may inform models for modulating melanocyte behavior in vivo.
October 2023 in “Oncotarget” In this study using live mice, researchers observed that during hair follicle regression, apoptosis in basal cells may propagate by triggering neighboring cells, potentially regulated by a gradient of pro-survival signals from stem cells, and proposed a testable mechanism to further explore this process.
June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that fibrosis-associated trochanters in central centrifugal cicatricial alopecia are enriched with hair follicle stem cells and may indicate a disrupted stem cell niche contributing to scarring.
29 citations
,
April 1997 in “Developmental Dynamics” This study found that topical trypsin application after hair removal in mice led to cell death at the follicular papilla, which delayed hair growth and pigmentation.
19 citations
,
August 1996 in “British Journal of Dermatology” This study found that dermal papillae in alopecia areata, including clinically normal follicles, exhibited ultrastructural abnormalities that suggest an early pathological role in the disease's development.