5 citations
,
January 2024 in “Aesthetic Surgery Journal Open Forum” This review notes that while ATX-101 showed a favorable safety profile for reducing submental fat in clinical trials, serious adverse events related to procedures have been reported in real-world use, prompting recommendations for improved management and prevention strategies.
26 citations
,
December 2021 in “Regenerative Biomaterials” This study found that an injectable ceria-based nanocomposite hydrogel improved wound healing and epithelium regeneration, including hair follicle and adipocyte tissue formation, in full-thickness skin wound models.
92 citations
,
September 2015 in “Journal of Lipid Research” This review discusses the roles of dermal white adipose tissue (dWAT) as an insulator, antibiotic, and regenerative tissue, highlighting its importance in systemic metabolism and immune function, but reports no new clinical results.
1 citations
,
April 2025 in “Materials Today Communications” In this study, researchers developed a composite electrospun dressing with fiber gradient changes that mimics skin's natural structure, demonstrating enhanced wound healing, collagen deposition, and reduced fibrosis and scarring in both in vitro and in vivo experiments.
January 2026 in “Advanced Science” In this study, a chronotherapeutic bilayer dressing system showed enhanced diabetic wound healing in a model by reducing inflammation through polyphenols and promoting repair with sustained PDGF-BB delivery, leading to faster re-epithelialization and hair follicle regeneration.
14 citations
,
May 2021 in “Marine Drugs” This review discusses the therapeutic properties of polydeoxyribonucleotides derived from marine organisms for wound healing and inflammation, but it reports no new clinical results.
2 citations
,
February 2016 in “The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology” In this study, Gagamyeonryunggobon-dan treatment improved hair regrowth in ICR mice, as evidenced by increased hair thickness, sebaceous gland development, capillary formation, and markers of hair follicle activation.
11 citations
,
May 2009 in “Medical Hypotheses” This paper proposes a theory explaining how the normal anabolic effects of androgens lead to structural changes and hair follicle miniaturization, contributing to androgenic alopecia.
32 citations
,
June 2003 in “The American Journal of Dermatopathology” This report describes the third known case of lipedematous scalp in a 51-year-old woman, marked by progressive thickening of the scalp without hair loss, and notes its association with early meningitis symptoms.
May 2023 in “Current Applied Science and Technology” In this animal study, researchers found that exposure to a CO2 laser at various power levels caused significant skin damage in rats, including severe burns, coagulation, and tissue obliteration, with higher laser doses resulting in more pronounced injuries.
87 citations
,
February 2004 in “Plastic and Reconstructive Surgery” In this study, researchers achieved complete reepithelialization and hair growth on a burn-injured scalp using a tissue-engineered dermal template with early micrograft hair follicle implantation.
90 citations
,
February 2013 in “The Journal of Clinical Endocrinology and Metabolism” This study found that women with polycystic ovary syndrome have higher global adiposity and increased visceral fat, particularly in the ip and mesenteric depots, compared to women without androgen excess.
April 2023 in “Digital Library of Theses and Dissertations (Universidade de São Paulo)” This study concluded that mesenchymal stem cells from adipose tissue harvested using laser-assisted liposuction with selective photo-stimulation are as effective and low-risk for cell therapy as those obtained through conventional liposuction, based on their differentiation potential, cellular proliferation, and cytokine expression.
14 citations
,
April 2017 in “Scientific Reports” This study demonstrated that using a perfusion culture bioreactor and 3D spheroid culture can enhance corneal endothelial cell expansion and support the construction of tissue-engineered corneal endothelial layers in vitro.
14 citations
,
January 2021 in “Scientific Reports” This study found that "micro skin tissue columns" improved wound healing by enhancing re-epithelialization, collagen deposition, dermal remodeling, and reducing inflammation without causing long-term donor site morbidity.
49 citations
,
March 2019 in “Journal of Investigative Dermatology” This review discusses dermal white adipose tissue's roles in skin immunity, highlighting its antimicrobial function and interactions with other immune cells, but reports no new clinical results.
16 citations
,
April 2015 in “Lasers in Surgery and Medicine” In this study, the researchers found that the effectiveness of a 1,550-nm fractional laser in promoting hair growth in mice depends on the specific combination of beam energy and density, with inappropriate settings potentially causing ulcers or hair follicle injury.
28 citations
,
February 2014 in “PLoS ONE” This study reports that transplantation of an ESCs-collagen-chitin biomimetic membrane leads to successful in situ skin regeneration, including hair follicle cell proliferation and formation of dermatoglyphs, in nude mice with full-thickness skin defects.
14 citations
,
January 2014 in “Cells Tissues Organs” This study found that single high-dose irradiation in mice induced more severe acute skin injury and hair depigmentation, while fractional doses led to longer-term damage in the dermis and subcutis.
97 citations
,
May 2008 in “Journal of Cutaneous Pathology” This review highlights the challenges in identifying histological features of adverse reactions to soft tissue fillers and emphasizes the need for increased awareness due to product uncertainty and delayed reactions.
132 citations
,
January 2017 in “International Journal of Molecular Sciences” This review explores how adipose-derived stem cells contribute to skin homeostasis and highlights recent advances in their clinical applications in dermatology, but it reports no new clinical results.
June 2026 in “International Journal of Bioprinting” This review found that 3D bioprinting significantly advances skin tissue engineering by enabling the creation of complex, patient-specific skin structures, though technological and regulatory challenges persist, particularly in areas like scalability and physiological mimicry.
13 citations
,
January 2016 in “Burns & Trauma” This review discusses the effects of vacuum massage on skin structures and concludes that there is insufficient evidence for its efficacy in treating burn scars, suggesting more research is needed on its potential benefits and mechanisms.
17 citations
,
June 2018 in “Frontiers in Physiology” This study found that acellular dermal matrix scaffolds may facilitate full-thickness skin wound healing by promoting a pro-regenerative immune response through M2 macrophage polarization via the Lamtor1 pathway.
41 citations
,
January 2020 in “BioMed Research International” This study found that micrografts containing human hair follicle mesenchymal stem cells significantly increased hair count and density compared to placebo over 58 weeks in patients experiencing hair loss.
16 citations
,
April 2016 in “PLoS ONE” In a porcine model, this study observed that using an External Tissue Expansion Device increased epidermis thickness, cell proliferation, and vessel density at fat graft recipient sites.
3 citations
,
January 2022 in “PLoS ONE” In this study using a rat full-thickness burn model, the amnion bilayer dressing showed better healing and skin recovery than the standard protocol, including quicker complete healing and restored skin appendages.
This study found that in a rat model of alopecia, combining low-level laser therapy with Neoptide treatment resulted in better hair regrowth compared to either treatment used alone.
The study found that adipose-derived mesenchymal stem cells obtained via laser-assisted liposuction with selective photo-stimulation are comparable in differentiation potential and tumorigenic risk to those from conventional liposuction for cell therapy applications.
77 citations
,
July 2013 in “Best Practice & Research in Clinical Obstetrics & Gynaecology” This review discusses the impact of menopause-related oestrogen deficiency on skin ageing and suggests that oestrogen use may improve collagen and skin elasticity, but it reports no clinical trial results.