160 citations,
April 2008 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism” DHT in the human prostate is produced through multiple pathways, not just from testosterone.
146 citations,
January 2004 in “Hormones” Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.
January 2024 in “Biology of sex differences” Dihydrotestosterone makes arteries stiffer in female mice by reducing estrogen receptor expression.
December 2013 in “Iranian Journal of Applied Animal Science” Adding bentonite clays to goat diets increased milk yield, periwinkle shell improved chicken egg production, and vaccination increased muscle area and carcass yield in calves.
204 citations,
February 2000 in “Current Medicinal Chemistry” Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.
22 citations,
October 2011 in “Bone” Androgens affect bone and fat cell development differently based on the cells' embryonic origin.
67 citations,
July 2016 in “Reviews in Endocrine and Metabolic Disorders” Stress can worsen skin conditions by affecting hormone levels and immune response.
53 citations,
June 2017 in “Skin appendage disorders” PRP treatment helps hair growth in most cases, but more research needed.
35 citations,
February 1994 in “Fundamental and applied toxicology” High doses of finasteride cause cell growth and tumors in mice.
32 citations,
November 1996 in “International Journal of Dermatology” Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.
15 citations,
April 2008 in “Steroids” The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.
9 citations,
March 1991 in “Endocrinology” Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.
3 citations,
January 1994 in “Toxicological Sciences” Finasteride causes abnormal growth in male mice cells at high doses.
153 citations,
October 2012 in “Skin Pharmacology and Physiology” Caffeine in cosmetics may reduce cellulite, protect skin, and stimulate hair growth, but more research is needed on its use and effects.
152 citations,
December 2007 in “Gender Medicine” Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.
44 citations,
November 1998 in “Australasian Journal of Dermatology” Accurate diagnosis is key for treating different kinds of hair loss, and immune response variations may affect the condition and treatment results.
28 citations,
March 2014 in “International Journal of Nanomedicine” New lipid nanoparticles show promise for delivering hair loss treatments but need improvement for better skin penetration.
23 citations,
January 2020 in “Frontiers in Pharmacology” Dihydrotestosterone affects hair growth by changing the Wnt/β-catenin pathway, with low levels helping and high levels hindering growth.
16 citations,
July 1992 in “The journal of experimental zoology/Journal of experimental zoology” Adrenal glands delay the start of winter fur growth in mink.
14 citations,
March 2018 in “Translational Stroke Research” Finasteride helps protect brain in old male rats.
13 citations,
October 2012 in “InTech eBooks” Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.
13 citations,
December 1991 in “Annals of the New York Academy of Sciences” Researchers created a lab model to study human hair growth, showing it can grow and self-regulate outside the body.
11 citations,
August 2018 in “Facial Plastic Surgery Clinics of North America” Adipose-derived stem cells show potential for skin rejuvenation and wound healing but require more research to overcome challenges and ensure safety.
11 citations,
January 2018 in “RSC Advances” Cedrol cream is more effective and safe for promoting hair growth than traditional treatments.
10 citations,
April 2016 in “Research and reports in transdermal drug delivery” Transfollicular drug delivery is promising but needs more research to improve and understand it better.
10 citations,
June 2005 in “Small ruminant research” Melatonin treatment may increase cashmere production in Spanish goats.
10 citations,
April 1995 in “Animal Science/Animal science” Melatonin implants can change the seasonal prolactin levels and hair growth in adult cashmere goats but not in juveniles, and don't delay spring moult for better fiber harvesting.
9 citations,
November 2011 in “Cytokine” Finasteride helps reduce lung inflammation and damage after trauma and infection.
8 citations,
January 1996 in “Springer eBooks” Male pattern baldness may be caused by factors like poor blood circulation, scalp tension, stress, and hormonal imbalances, but the exact causes are still unclear.
4 citations,
November 2022 in “Frontiers in endocrinology” The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.