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Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.

Women with the NIH type of PCOS have more obesity and higher risk of diabetes and heart disease than those with other types of PCOS.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Hidradenitis suppurativa, a chronic skin disease, can be managed with antibiotics, lifestyle changes, and in severe cases, surgery. Early diagnosis and careful planning are key, and laser treatment can be an efficient solution for mild to severe cases.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.

Oestrogens are key for bone growth during puberty in both boys and girls.

A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.

Low-Level Laser Therapy is effective and safe for hair growth with minimal side effects.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Women with PCOS have heart-related issues not because of obesity, but due to insulin resistance and low adiponectin levels.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.

Probiotic bacteria improved skin and hair health in aged mice.

Surgeons must understand the full care process for gender confirmation surgery to help transgender individuals effectively.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.

Melatonin helps regulate hair growth and protects the hair follicle from stress.