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The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Advanced human skin models improve drug development and could replace animal testing.

The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Skin problems are very common in people with end-stage kidney disease.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Hidradenitis suppurativa treatment should be tailored to the individual, with quitting smoking being important.

Stress increases certain chemicals in the skin and nerves, which might worsen skin conditions.

PRP injections may be a safe, effective alternative for hair loss treatment compared to minoxidil and finasteride.

Skin problems can be caused or worsened by physical forces and pressure on the skin.

Some systemic treatments work for nail psoriasis but can have serious side effects.

Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.

Noggin overexpression delays eyelid opening by affecting cell death and skin cell development.

Microneedle technology has improved drug delivery and patient comfort but needs more research for broader use.

Brain-Derived Neurotrophic Factor (BDNF) slows down hair growth and promotes hair follicle regression.

Technique creates 3D cell spheroids for hair-follicle regeneration.

Sebaceous glands in the skin play a key role in absorbing the antiandrogen drug RU 58841, especially when it's encapsulated in liposomes.

Coffee silverskin may be a beneficial and safe ingredient for cosmetics, offering hydration, firmness, and potential hair growth benefits.

The peptide IMT-P8 can effectively deliver proteins into the skin and cells for potential skin treatments.

Most patients with chronic kidney disease have skin problems, which get worse as the disease progresses, and dialysis doesn't greatly reduce these issues.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.

Researchers found 15 new genetic links to skin traits in Japanese women.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

Testosterone may slow down wound healing and increase inflammation.

Hair loss can indicate underlying systemic diseases and addressing these can sometimes reverse the hair loss.