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Platelet lysate is a promising, cost-effective option for regenerative medicine with potential clinical applications.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

There are various effective hormone treatments for puberty induction in boys and girls with hypogonadism, and starting treatment early is important.

Rare ULBP3 gene changes may raise the risk of Alopecia areata, a certain FAS gene deletion could cause a dysfunctional protein in an immune disorder, and having one copy of a specific genetic deletion is okay, but two copies cause sickle cell disease.

Polymeric microneedles offer a less invasive, long-lasting drug delivery method that improves patient compliance and reduces side effects.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

Scientists created a lab-grown hair follicle model that behaves like real hair and could improve hair loss treatment research.

Stem cells can improve wound healing, reduce scars, promote hair growth, rejuvenate skin, and enhance fat grafts in plastic surgery, but there are still some concerns.

Advancements in cosmetic and reconstructive surgery improve techniques and patient satisfaction.

B6.Cg-Tyr c−2J Hr hr /J mice have a stronger delayed sunburn reaction and are good for UV research.

The conclusion is that fat grafting is safe and effective but carries risks that need careful management.

The hairline lowering surgery with bone tunneling suture fixation is safe and effective, with high patient satisfaction.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

New skin substitutes for treating severe burns and chronic wounds are being developed, but a permanent solution for deep wounds is not yet available commercially.

More research is needed to understand how testosterone is maintained in adult males.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Cell transplantation faces challenges in genitourinary reconstruction, but alternative tissue sources and microencapsulation show promise.

The document concludes that understanding adult stem cells and their environments can help improve skin regeneration in the future.

Scientists are using clumps of special stem cells to improve organ repair.

Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.

The levonorgestrel implant increases free testosterone and lowers SHBG more than DMPA-IM and the copper IUD.

Artificial hair implantation using scaffolds is possible and PHDPE is more biocompatible than ePTFE.

Hormone therapy may increase migraines in transgender women and decrease them in transgender men; more research is needed on migraine management in transgender individuals.

P144® improves hypertrophic scars by reducing size and thickness and increasing elasticity.

Melatonin stimulates the skin components of ram's scrotum during their non-breeding season.

New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.

Platelet-Rich Plasma may improve skin health and reduce wrinkles, but more research is needed for standard treatment guidelines.