June 2023 in “Research Square (Research Square)” This study found that polycaprolactone (PCL) in facial fillers led to more cell proliferation and vascular activity than hyaluronic acid (HA) in Wistar rats, suggesting enhanced tissue regeneration effects with PCL.
June 2019 in “The Egyptian Journal of Histology” In this study, hyaluronic acid filler injections in albino rats increased subcutaneous tissue thickness, collagen and elastic fibers, and vascularization, suggesting potential benefits for combating skin aging and defects.
97 citations
,
May 2008 in “Journal of Cutaneous Pathology” This review highlights the challenges in identifying histological features of adverse reactions to soft tissue fillers and emphasizes the need for increased awareness due to product uncertainty and delayed reactions.
81 citations
,
January 2003 in “Journal of cosmetic and laser therapy” This review discusses various techniques for treating post-acne scars, highlighting new laser technologies and tissue augmentation methods, but reports no new clinical results.
14 citations
,
August 2017 in “Dermatologic surgery” This review discusses strategies for achieving natural results in male facial aging treatments using dermal and subcutaneous fillers, but reports no new clinical outcomes.
49 citations
,
July 2007 in “Ophthalmic Plastic and Reconstructive Surgery” This report describes a case of granulomatous reaction to injectable poly-L-lactic acid in the periorbital area and suggests surgical excision as an effective treatment for persistent nodules.
12 citations
,
October 2015 in “Journal of bioactive and compatible polymers” This study found that keratin hydrogels extracted from human hair showed potential as biodegradable and biocompatible filler materials, promoting angiogenesis and cell proliferation in rat models.
June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” This pilot study suggests that a new preparation of platelet-rich plasma gel may improve symptoms and tissue regeneration in patients with en coup de sabre scleroderma, though further trials are needed to clarify its role.
April 2019 in “Journal of Investigative Dermatology” In this pilot study, combined platelet-rich plasma therapies showed potential benefits for improving skin elasticity and vascular network density in morphea patients, but the small sample size limits definitive conclusions.
6 citations
,
January 2018 in “Annals of dermatology/Annals of Dermatology” In this first reported case, a 42-year-old female with Parry Romberg Syndrome was treated using hyaluronic acid filler, which the authors suggest may serve as a safe, simple, and cost-effective alternative to more complex surgical methods.
126 citations
,
April 2015 in “Clinical, cosmetic and investigational dermatology” This review discusses best practices for minimizing complications with dermal fillers and provides guidance based on expert consensus, yet it reports no new clinical results.
26 citations
,
December 2020 in “Indian Journal of Plastic Surgery” This review discusses complications from hyaluronic acid filler treatments and explores their causes, presentation, and possible treatment guidelines, without presenting new results.
10 citations
,
August 2020 in “Indian Journal of Plastic Surgery/Indian journal of plastic surgery” This minireview discusses the mechanisms of facial aging, examines current literature, and proposes filler injection protocols, but it reports no new clinical results.
7 citations
,
April 2017 in “Dermatologic surgery” This study concluded that bimatoprost 0.03%, applied either twice or once daily, is safe, well-tolerated, and effective in improving eyebrow fullness and darkness in individuals with eyebrow hypotrichosis.
February 2026 in “Clinical Cosmetic and Investigational Dermatology” This case study reports significant hair regrowth in a 29-year-old female with filler-induced alopecia after treatment with concentrated growth factor injections, suggesting it as a promising alternative therapy to standard hyaluronidase injections.
15 citations
,
December 2015 in “Textile Research Journal” This study describes the development of polyamide 6 composite fibers with amber filler, finding them suitable for use in medical textiles such as compression garments due to their biocompatibility with skin cells.
22 citations
,
September 2018 in “Medical Clinics of North America” This article reviews the biological causes and treatment options for facial aging but reports no new clinical findings.
13 citations
,
December 2021 in “Toxics” In this study, PEGDE above 10,000 μg/mouse caused subcutaneous toxicity including ulceration in mice, but did not affect liver, spleen, or kidney tissues.
3 citations
,
November 2022 in “Facial plastic surgery & aesthetic medicine” In this study, researchers introduced an ultrasound-guided technique for injecting hyaluronic acid fillers into the temple area to enhance safety and precision by visualizing filler placement in the interfascial space.
2 citations
,
July 2020 in “Trends in Urology and Men's Health” This article discusses cosmetic surgeries offered to men in the UK and highlights potential risks but reports no new findings.
2 citations
,
November 2014 This chapter reviews common cosmetic dermatology techniques but presents no new findings; it discusses treatments like emollients and laser therapy for conditions like photoaged skin and acne scarring.
1 citations
,
January 2009 in “Elsevier eBooks” This chapter provides an overview of skin physiology, aging effects, and how environmental factors like UV damage impact skin health, without presenting new research findings.
November 2014 in “Springer eBooks” Using a patient's own tissue for browlifting can improve both the position and fullness of the brow for a longer-lasting rejuvenation.
69 citations
,
December 2016 in “Facial plastic surgery” This review discusses the anatomical and histological characteristics of facial fat compartments and reports no new clinical results, emphasizing a need for further research on their role in facial aging.
134 citations
,
June 2012 in “International Journal of Oral and Maxillofacial Surgery” This article discusses current methods in facial feminization surgery for transsexual women and reports no new clinical results, focusing instead on various surgical techniques used to feminize facial features.
65 citations
,
January 2017 in “Postępy Dermatologii i Alergologii” This review highlights the increasing clinical applications of high-frequency ultrasonography in dermatology, particularly for assessing the depth of skin tumors and monitoring inflammatory skin diseases, but reports no new clinical results.
38 citations
,
February 2016 in “Surgery Journal” This article discusses a wide range of procedures in facial plastic surgery and highlights the recent advancements and trends without reporting new clinical findings.
20 citations
,
December 2016 in “American Journal of Clinical Dermatology” This review discusses the most popular non-surgical cosmetic procedures for men and highlights the importance of considering sex-specific factors for optimal treatment, but reports no new clinical results.
15 citations
,
February 2016 in “Dermatologic Surgery” This study concluded that dermatology has made the most significant contributions to noninvasive and minimally invasive cosmetic procedures, while other specialties have also provided important literature in this field.
4 citations
,
October 2022 in “Aesthetic surgery journal” This study reports that percutaneous superficial temporal arterial hyaluronidase injection effectively treated necrosis of the frontotemporal skin and ipsilateral scalp, with patients experiencing significant recovery in skin appearance and hair regrowth 2 to 3 months after injection, following complications from hyaluronic acid filler.