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Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

Understanding how baby skin heals without scars could help develop treatments for adults to heal wounds without leaving scars.

The document suggests a personalized treatment plan for alopecia areata based on the patient's age and hair loss severity, using a range of therapies ranked by effectiveness and safety.

New insights into the causes and treatments for the autoimmune hair loss condition Alopecia areata have been made.

New treatments for COVID-19 show promise, but more effective antiviral drugs are needed.

The document concludes that Hidradenitis suppurativa is often underdiagnosed, lacks definitive treatment, and requires better awareness and management strategies.

Immune cells in Hidradenitis suppurativa become more inflammatory and may be important for treatment targets.

Different types of cell death affect skin health and inflammation, and understanding them could improve treatments for skin diseases.

Hidradenitis suppurativa is a skin disease caused by the breakdown of the skin's natural immune barriers, especially around hair follicles.

Retinoids are effective for various skin conditions and hair loss but have serious side effects, so low doses are recommended.

Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.

Biologic therapies can cause various adverse events, but allergy/immunology clinicians can manage them.

New treatments focusing on immune pathways show promise for stubborn hair loss.

PRO-C22 can help diagnose and monitor the severity of hidradenitis suppurativa.

Non-scarring alopecia in females affects emotional well-being and requires accurate diagnosis and personalized treatment.

New understanding and treatments for hair loss are improving, but more research is needed.

The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.

TNF-alpha inhibitors can cause various immune-related skin issues.

Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.

The Polish Society of Dermatology recommends treatments for alopecia areata that vary by severity, including topical and systemic medications, with long-term maintenance important for management.

Stopping adalimumab and starting methotrexate with topical treatments improved the woman's scalp psoriasis and hair regrew.

A patient's grey hair regained color during treatment with adalimumab.

A woman with severe hair loss was successfully treated with the drug adalimumab.

New treatments for a chronic skin condition show promise, but individualized plans are crucial due to varying responses.

Tofacitinib citrate is effective for moderate-to-severe chronic plaque psoriasis but has safety concerns at higher doses.

Dupilumab for eczema may cause hair loss.

Some medications might reverse gray hair, especially those that reduce inflammation or stimulate pigment production, and vitamin B might help.

A young woman had a rare skin reaction to a medication for her joint disease, and a combination therapy improved her condition.

Finasteride helped treat a 28-year-old's facial skin condition.

Secukinumab can cause hair loss, which may improve after stopping the medication.