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Removing the ATR gene in adult mice causes rapid aging and stem cell loss.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Natural products in cosmetics are beneficial for skin and hair care with low toxicity.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Hair and nail cells share similar proteins, indicating a common differentiation pathway.

Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.

The research found that different types of fibroblasts are involved in wound healing and that some blood cells can turn into fat cells during this process.

Stem cell-derived conditioned medium shows promise for treating various medical conditions but requires standardized production and further validation.

TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Niosomes are a promising, stable, and cost-effective drug delivery system with potential for improved targeting and safety.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Hair growth and pigmentation in mice involve specific stages crucial for research.

Middle-aged women with chronic telogen effluvium experience increased hair shedding but usually don't get significantly thinner hair.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Nerves are crucial for the regeneration of various body parts in many animals.

Androgen deprivation therapy for prostate cancer can cause sexual, physical, and psychological side effects, and doctors should manage these carefully.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

The document provides a method to classify human hair growth stages using a model with human scalp on mice, aiming to standardize hair research.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.