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This study found that excessive heat caused the most significant structural changes in hair from Caucasian and Afro samples, especially when combined with other treatments like bleaching and straightening.

This review discusses recent advances in surface modification and endothelialization of biomaterials for vascular grafts, highlighting promising methods like gene engineering and targeting ligand immobilization to improve clinical outcomes.

This study reported new crystallographic structures and polymorphs of finasteride, including several solvates with distinct X-ray diffraction patterns and thermally characterized properties.

This study examined the structural and biochemical mechanisms of human lipocalin prostaglandin D synthase, detailing substrate and product binding processes at the catalytic site and suggesting potential for drug delivery targeting hydrophobic molecules.

This study found that higher concentrations of copper (II) ions in human hair increase protein oxidative modification, contributing to hair damage regardless of UV exposure and pigmentation level.

This study found that solid-state NMR combined with X-ray techniques provided critical insights into the structure and solvation of finasteride polymorphs, identifying gaps in existing patent characterizations.

This chapter provides an overview of the complex chemical and physical structure of the hair surface, detailing how factors like ethnicity, environmental stress, and cosmetic treatments can alter its properties and influence the adhesion of hair care products.

This study optimized the extraction process for abomasum protein from Tianshan red deer, identifying two proteins with anti-inflammatory and anti-tumor activities, suggesting they could be beneficial in foods and nutraceuticals.

This study investigated the molecular mechanisms behind the formation of drug-polymer inclusion complexes and found that carbamazepine can self-assemble into stable channel structures without guest polymers, unlike griseofulvin, which requires guest molecules for structural stability.

This research elucidates the molecular mechanisms underlying carbamazepine and griseofulvin's inclusion complex channel formations with polymers, revealing why carbamazepine forms stable channels independently, while griseofulvin requires polymeric support due to weaker interactions.

This study explored the structure and function of lipocalin prostaglandin D synthase, revealing its dual role in substrate catalysis and as a lipophilic ligand carrier, potentially informing future drug delivery design.

This study found that specific mutations in the spike protein of SARS-CoV-2 may significantly alter its structure and affect how it binds to certain inhibitors, but experimental studies are needed to confirm potential clinical implications.

This study provides the first crystal structure of the human SRD5A2 enzyme, revealing key insights into its function and inhibition which may aid future drug development.

This study developed an advanced HPLC-ESI-ion trap MS(n) method for the structural identification of cyclosporin A analogs CyA and CyC and reported the first MS(n)-aided identification of a new CyA analog.

This chapter discusses the structure and function of the skin, detailing its protective roles and the layers that comprise it, but reports no new research findings.

Understanding skin structure and development helps diagnose and treat skin disorders.

This study found that octahydrobenzo[c]quinolizin-3-one derivatives, particularly compound 3, were potent and selective inhibitors of the enzyme 5α-reductase type 1.

Finasteride modifies 5-alpha-reductases through a two-step process, affecting inhibitor potency and possibly causing side effects.

This review highlights the crucial role of histone modification in the pathogenesis and treatment of chronic inflammatory skin diseases, and explores therapeutic strategies targeting these epigenetic changes to improve management of conditions such as psoriasis and atopic dermatitis.

In this study, experimentally induced weight loss in merino sheep led to a decrease in wool fiber diameter and increased expression of certain high sulfur and glycine-tyrosine proteins, potentially impacting wool quality and industry preferences.

This study analyzes the fine structure and protein distribution in monotreme hairs, finding similarities with other mammals and detailing unique immunocytochemical features in their inner root sheaths.

This review discusses the challenges in identifying specific hair follicle antigens involved in initiating alopecia areata and highlights the need for further research to understand its etiopathogenesis, reporting no new results.

This study found that MDA-modified DNA may contribute to immune responses in alopecia areata patients by creating neo-epitopes, providing new insights into the condition's immunological mechanisms.

This study found that METTL1 is upregulated in papillary thyroid cancer tissues and promotes cancer cell proliferation and metastasis through its tRNA methyltransferase activity.

This study found that m6A-circRNA-ZNF638 enhances the activation of secondary hair follicle stem cells in cashmere goats by interacting with the miR-361-5p/Wnt5a pathway.

This study identified the N-(iodopropenyl) derivative 13 as a promising candidate for development as a radioiodinated androgen receptor ligand due to its binding affinity.

This review presents updated tables of mouse mutants with hair growth abnormalities to aid in understanding the molecular mechanisms of human hair disorders, but reports no new clinical results.

This chapter reviews the skin's structure and its clinical relevance, highlighting connective tissue diseases and the potential for novel treatments like protein, cell, or stem cell transfer, but reports no new findings.

This study found that white hair fibers have lower lipid content and different water absorption dynamics compared to brown hair fibers, suggesting differences in their barrier functions.

In this study, researchers observed that mice with the naked gene showed frequent absence of hair cuticle and cortical cells during follicle growth, with abnormal keratin deposition also noted.