3 citations
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October 2022 in “PloS one” This study developed a method to culture and maintain chicken feather follicles in vitro, preserving structure and biology similar to their in vivo state, though some gene expression was altered.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This study examined how different hair dye processes affect hair structure at a molecular level, finding that oxidative dyes increase keratin porosity more than non-oxidative dyes, and highlighted emerging technology aimed at reducing hair damage while preserving color quality.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, researchers investigated how different hair dye processes affect hair structure, finding that oxidative dyes disrupt hair more than semi-permanent dyes, and emerging technologies could help maintain hair health while achieving desired color.
November 2025 in “International Journal of Science and Research Archive” This study reviews how different hair dyeing methods affect hair structure, showing oxidative dyes cause more structural damage than semi-permanent dyes, while new technologies aim to minimize harm while preserving color.
1 citations
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January 2021 in “Brazilian Journal of Medical and Biological Research” In this study, maternal exposure to constant light significantly altered the neonatal skin structure in rabbits, associated with reduced maternal melatonin levels.
6 citations
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January 2025 in “RSC Medicinal Chemistry” This review discusses the signaling mechanisms of RAAS, the current drugs targeting RAAS, their limitations, and suggests innovative strategies for developing new therapeutics but reports no new results.
43 citations
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July 1994 in “Journal of Cell Science” This study found that the extraction-resistant structures in hair, feathers, and hagfish teeth are due to ε-(γ-glutamyl)lysine cross-linked proteins, emphasizing their role in maintaining the integrity of these materials.
2 citations
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July 2012 in “PubMed” In this study, the use of internal wool lipid liposomes was shown to improve the lipid composition and increase the resistance to breaking in both untreated and chemically treated hair fibers.
75 citations
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April 2000 in “Developmental Dynamics” This study suggests that the structural integrity and physical proximity of Whn's DNA binding and activation domains are crucial for hair keratin gene activation and may explain the nude phenotype.
36 citations
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November 2019 in “Molecular biology and evolution” This study suggests that the keratins found in reptile and bird skin appendages evolved independently from mammalian hair keratins, highlighting convergent evolution in these species.
28 citations
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November 2009 in “Journal of Structural Biology” This study found that the molecular structure of hair is more sensitive to synchrotron X-ray radiation than its supramolecular architecture, indicating potential concerns for biological analyses using such radiation.
13 citations
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November 2012 in “International Journal of Dermatology” This study of African-American women found that those perceiving greater hair breakage showed lower break stress and higher premature failure rates, linked to grooming practices and hair curvature.
January 2025 in “Dermatology Research and Practice” This study found that using 369LAB Lipid Bond, derived from plant oil triglycerides, can restore lipid content in damaged hair to natural levels and improve hair strength, integrity, and resilience after a single application, with benefits persisting even after discontinuation.
1 citations
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March 2006 in “The FASEB journal” This study found that keratin scaffolds derived from human hair promoted excellent cell viability and showed minimal inflammatory response and vascular integration when tested in in vitro and in vivo settings.
122 citations
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June 2002 in “Genes & Development” This study found that K17 is crucial for the structural integrity and survival of hair-producing cells, with K17 null mice developing alopecia due to hair fragility and follicular alterations.
59 citations
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July 1972 in “Biochemistry” This study investigated the formation of a specific chemical crosslink in hair proteins and explored the role of transamidase enzymes in hair follicles.
46 citations
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January 2020 in “Research” This review discusses the design, properties, and potential applications of smart microneedles, with no new clinical results presented.
January 2026 in “Physical Education Health and Social Sciences” This study found that integrating Lactobacillus-rich probiotic nutrition and fractional CO₂ laser therapy with clotrimazole in mucoadhesive hydrogels significantly improved clinical and structural outcomes for women with recurrent vulvovaginal candidiasis, suggesting a promising advanced therapy, though further validation in larger trials is needed.
January 2025 in “International Journal of Cosmetic Science” This study found that citric acid treatment can significantly improve the structural integrity and mechanical properties of chemically treated hair, reducing damage by increasing keratin crosslinking density and decreasing crystallized calcium soaps, with varying effectiveness depending on the type of chemical treatment.
40 citations
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July 2019 in “Journal of Investigative Dermatology” In this study, knockout mice lacking the Cyp4f39 gene showed severe skin barrier dysfunction and high early mortality, suggesting its critical role in skin barrier formation and insights into ichthyosis pathogenesis.
29 citations
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August 2011 in “PubMed” This study found that selected polymeric pretreatments on hair can significantly reduce breakage and protect against thermal damage from hot flat irons by maintaining cuticle integrity and moisture.
15 citations
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May 2014 in “Journal of Biological Chemistry” In this study, targeting the expression of a keratin KRT5/KRT8 chimeric cDNA in keratin-deficient mice partially restored structural defects in epidermal cells, but did not fully normalize skin health.
This study found that scalp cooling effectively prevented visible hair loss in over half of patients undergoing highly alopecia-inducing chemotherapy, yet cognitive appraisal of the treatment had a more significant impact on quality of life than the actual degree of hair retention.
4 citations
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December 2020 in “Mammalian genome” This study found that pelage abnormalities in Harlequin mutant mice are linked to severe AIF deficiency and associated with altered expression of genes related to hair structure.
1 citations
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November 2023 in “Polymer International” This study found that integrating graphene oxide into a biodegradable composite made from discarded hair keratin enhanced its structural properties, biodegradability, and gas barrier performance, indicating potential use as an eco-friendly packaging material.
August 2026 in “Lasers in Medical Science” This review suggests that hyperspectral and terahertz imaging show promise in non-invasively assessing scalp changes associated with hair loss, but further validation is needed for clinical application.
47 citations
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December 2003 in “Journal of Investigative Dermatology” DS cells in hair follicles can help form and restore hair, especially in hair loss conditions.
68 citations
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April 2014 in “Journal of Investigative Dermatology” This study identified a new S100 fused-type protein, scaffoldin, in reptiles and birds and suggests that SFTP-positive epithelia serve as scaffolds for the growth of various skin appendages, indicating a common evolutionary origin.
8 citations
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January 2023 in “International journal of molecular sciences” This study reveals that transglutaminase activity is widespread in integumentary structures of mammals and birds, suggesting it plays a significant role in the cornification of hard skin appendages like nails and feathers.
2 citations
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September 2023 in “International journal of molecular sciences” This review summarizes the roles of matricellular proteins in skin stem cell niches, highlighting their contribution to stem cell fate, self-renewal, and potential implications for wound healing and aging.