April 2025 in “Journal of Pharma Insights and Research.” This review examines ultrasound-assisted and laser-based transdermal drug delivery technologies, highlighting their success in enhancing drug penetration through the skin but also noting challenges such as parameter optimization, potential skin irritation, and high equipment costs.
Results are not reported in this abstract, which outlines a book by Dr. Edward Luce that introduces a modular curriculum for plastic surgery training, aiming to revolutionize education by prioritizing cognitive understanding, skill development, and interactive learning methods fit for modern residency programs.
226 citations
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May 2004 in “Journal of Biological Chemistry” This study identified collagen XXII as a novel extracellular matrix protein specifically present at tissue junctions, where it functions as a cell adhesion ligand for skin epithelial cells and fibroblasts.
108 citations
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October 2003 in “Journal of biological chemistry/The Journal of biological chemistry” This study documents that trichohyalin acts as a multi-functional cross-bridging protein in the inner root sheath of mouse hair follicles, enhancing mechanical strength by linking keratin filaments to the cell envelope.
69 citations
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January 2009 in “Advances in Materials Science and Engineering” This study demonstrated that keratin can be effectively extracted from wool using alkaline solutions and that the extracted keratin maintains reactivity similar to that from other low-value sources like cattle hair.
47 citations
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November 2007 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” This review discusses how various factors, including cosmetic procedures and scalp conditions, can damage hair, but highlights the availability of products to improve hair health; it reports no new empirical results.
45 citations
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May 2003 in “Journal of Cell Science” This study found that α3β1-integrin is crucial for maintaining normal hair follicle morphology in mice, as its deficiency leads to severe abnormalities despite not affecting interfollicular epidermal differentiation.
32 citations
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March 1988 in “International Journal of Dermatology” This review discusses current concepts on the role of retinoids in keratinization and does not report new clinical results; the authors emphasize the complexity of retinoid effects on skin.
31 citations
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August 2023 in “ACS Applied Bio Materials” This study developed granular hydrogels with reversible interparticle cross-linking, finding they offer high mechanical stability and enhance cell recruitment, making them promising for injectable and 3D printable scaffolds in tissue engineering and therapeutic delivery.
30 citations
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December 2021 in “Frontiers in Microbiology” In this study, researchers found that cepharanthine significantly inhibited HSV-1 replication in vitro by interfering with specific signaling pathways, arresting the cell cycle, and inducing apoptosis in infected cells, highlighting its potential as an antiviral agent.
29 citations
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May 2025 in “Polymers” This study systematically examines how smart biomaterials used with DLP technology can enhance bioprinting in tissue engineering and regenerative medicine, while also identifying current challenges and future research needs.
28 citations
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December 1997 in “Journal of Biological Chemistry” This study found that the hHa1-t protein variant, caused by a genetic polymorphism in the hHa1 gene, forms functional keratin filaments despite lacking a complete nonhelical tail domain, explaining the absence of a pathological hair phenotype.
25 citations
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August 2024 in “Virtual and Physical Prototyping” This review outlines various 3D bioprinting techniques and bioinks used for creating artificial tissues and organs, emphasizing their potential in addressing organ transplant shortages and advancing drug testing, while acknowledging existing challenges and future prospects.
23 citations
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January 1986 This review discusses the chemical stability of protein envelopes found in the epidermis and other stratified squamous epithelia, but reports no new clinical results.
14 citations
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July 1994 in “Journal of Dermatological Science” In this study, transgenic mice expressing a mutant K6 gene developed progressive scarring alopecia and keratosis, suggesting they may model a new keratin disorder.
8 citations
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March 2018 in “Cosmetics” In this study, researchers found that UV radiation causes hydroxy radicals to form cuticle holes specifically between the cuticle layers in wet hair, unlike random holes caused by Fenton's reaction.
7 citations
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September 2021 in “Journal of Applied Polymer Science” This study found that melanin extracted from cuttlefish ink provided significant protection against UV radiation damage to human hair, suggesting its potential as a photoprotective agent in hair-care products.
2 citations
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September 2021 in “JCPSP. Journal of the College of Physicians & Surgeons Pakistan” In this study, researchers observed that while there were no significant microvascular abnormalities in the macula of PCOS patients, the parafoveal thickness was significantly increased in most quadrants.
2 citations
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May 2017 in “International journal of pharmacy and pharmaceutical sciences/International Journal of Pharmacy and Pharmaceutical Sciences” This review discusses genetic mutations associated with Hutchinson-Gilford progeria syndrome and reports no clinical results; the authors emphasize the importance of cardiovascular monitoring in management.
2 citations
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July 2015 in “Archives of Dermatological Research” This study reports the first familial case of alopecia linked to a novel homozygous variant in the DSP gene, which did not coincide with heart abnormalities despite prior associations.
1 citations
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February 2025 in “International Journal of Molecular Sciences” This study found that an enzymatic digestion method for isolating hair follicle stem cells from scalp specimens yielded 5.3 times more epithelial cells than explant cultures, while supporting comparable cell functionality, offering a promising technique for tissue engineering and regenerative medicine.
1 citations
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April 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study is the first to document alopecia in Guadalupe fur seals in the Northeast Pacific Ocean, finding that it may result from nutritional stress due to higher sea surface temperatures.
August 2026 in “Journal of the Korean Society of Cosmetology” In this study, researchers observed that Sedum takesimense extract improved the surface properties, moisture retention, tensile strength, and wave formation of damaged hair compared to a water control, even after additional chemical and UV damage, suggesting its potential as a protective hair treatment.
July 2026 in “Scientific Reports” This study found that wool felting in Ukrainian Carpathian Mountain sheep is linked to significant changes in fatty acid composition, particularly highlighting a decrease in 18-methyleicosanoic acid in bound lipids, suggesting it as a potential marker for cuticle lipid layer damage during felting.
July 2026 in “Advanced Science” In this study, researchers found that a scallop adhesive protein (Sbp9 Δ) forms strong adhesive coatings via disulfide-sticker strategies, which also promote hair regeneration in mouse models by activating Wnt signaling and enhancing angiogenesis, proving more effective than minoxidil for androgenetic alopecia.
April 2026 in “IntechOpen eBooks” The researchers presented a case study on Exo.Reset®, a cosmetic formulation using extracellular vesicle technology, demonstrating systematic application of recognized standards to ensure scientific rigor and regulatory compliance in skin rejuvenation product development, providing a practical model for EV-based cosmetic innovations.
January 2026 in “Bioengineering” In this review, various expression systems for synthesizing recombinant collagen are compared, highlighting their efficiency, modification capabilities, and cost. Key purification techniques are also analyzed, and challenges like reducing R&D costs and improving safety protocols are identified.
August 2025 in “BMC Genomics” In this study, researchers found distinct gene expression patterns in Standardbred trotters capable of racing barefoot, suggesting a genetic basis for hoof strength and identifying specific genes involved in hoof biology, which could enhance equine performance and wellbeing through targeted genetic research.
May 2024 in “International Journal of Cosmetic Science” This review highlights that hair's chemical bonds, particularly disulfide bonds, are not homogeneous, as previously thought, but instead vary in response to different cosmetic treatments, suggesting a need for further exploration of ionic bonds and hydrophobic interactions.
December 2021 in “Figshare” This study found that BBS7 is downregulated in occlusal hypofunctional periodontal ligament, suggesting it plays a crucial role in maintaining Shh signaling for PDL homeostasis.