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African spiny mice can regenerate skin, hair, and cartilage, but not muscle, and their unique abilities could be useful for regenerative medicine.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Polysaccharides have many health benefits and are used in drugs, but isolating and purifying them is complex and requires careful methods.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Stem cell niches support, regulate, and coordinate stem cell functions.

Peptide hydrogels heal burn wounds faster and better than standard dressings.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Microneedling is promising for treating various skin issues but needs more research to confirm its effectiveness and safety.

The document concludes that hair is complex, with a detailed growth cycle, structure, and clinical importance, affecting various scientific and medical fields.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

Platelet-rich plasma might help tissue regeneration in dentistry, but results vary and more research is needed.

Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.

Skin has specialized touch receptors that can tell different sensations apart.

Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

Dermatologists need to understand African American hair-care practices to better treat their hair and scalp disorders.

Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.

Dermatoscopy is a useful tool for diagnosing hair disorders and can help choose samples for more detailed analysis.