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Removing the ATR gene in adult mice causes rapid aging and stem cell loss.

Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Targeting colon cancer stem cells might lead to better treatment results.

Some wound-healing cells can turn into fat cells around new hair growth in mice.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The research found that PCOS has common genetic factors regardless of how it is diagnosed and is linked to metabolic and reproductive issues.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

The research found that different types of fibroblasts are involved in wound healing and that some blood cells can turn into fat cells during this process.

Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.

Stem cell-derived conditioned medium shows promise for treating various medical conditions but requires standardized production and further validation.

Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

PCOS is caused by both genetics and environmental factors like diet and obesity.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Diagnosing PCOS in teenagers is challenging and should use strict criteria to avoid misdiagnosis and unnecessary worry.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.

Targeted cancer therapies often cause serious skin problems that need careful management.

Special fiber materials boost the healing properties of certain stem cells.

The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.

Stem cell niches support, regulate, and coordinate stem cell functions.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.